sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1t91 | GTP | Ras-related protein Rab-7a |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1t91 | GTP | Ras-related protein Rab-7a | / | 1.000 | |
| 1yhn | GTP | Ras-related protein Rab-7a | / | 0.587 | |
| 3e5h | GNP | Ras-related protein Rab-28 | / | 0.574 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.573 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.570 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.557 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.554 | |
| 1vg8 | GNP | Ras-related protein Rab-7a | / | 0.552 | |
| 1zbd | GTP | Ras-related protein Rab-3A | / | 0.527 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.523 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.495 | |
| 4lhw | GNP | Ras-related protein Rab-8A | / | 0.495 | |
| 4o25 | GTP | GTP-binding protein Rheb | / | 0.494 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.486 | |
| 2zet | GTP | Ras-related protein Rab-27B | / | 0.484 | |
| 3lbn | GNP | GTPase HRas | / | 0.482 | |
| 3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.470 | |
| 3tso | GNP | Ras-related protein Rab-25 | / | 0.469 | |
| 5dha | GNP | GTP-binding nuclear protein Ran | / | 0.469 | |
| 3ea5 | GDP | GTP-binding nuclear protein Ran | / | 0.467 | |
| 5jlj | GNP | GTP-binding nuclear protein Ran | / | 0.466 | |
| 3i3s | GNP | GTPase HRas | / | 0.464 | |
| 3rab | GNP | Ras-related protein Rab-3A | / | 0.464 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.462 | |
| 3bc1 | GNP | Ras-related protein Rab-27A | / | 0.457 | |
| 3v4f | GNP | GTPase HRas | / | 0.453 | |
| 1g17 | GNP | Ras-related protein SEC4 | / | 0.452 | |
| 3oiu | GNP | GTPase HRas | / | 0.452 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.451 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.451 | |
| 1oix | GDP | Ras-related protein Rab-11A | / | 0.450 | |
| 3nbz | GTP | GTP-binding nuclear protein Ran | / | 0.449 | |
| 4nyj | GNP | GTPase HRas | / | 0.449 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.448 | |
| 3a6p | GTP | GTP-binding nuclear protein Ran | / | 0.448 | |
| 3rs5 | GNP | GTPase HRas | / | 0.447 | |
| 5b2z | GNP | GTPase HRas | / | 0.447 | |
| 3a58 | GNP | GTP-binding protein RHO1 | / | 0.441 |