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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1svhI08cAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.640
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.602
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.582
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.580
1xh4R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.569
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.563
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.562
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.561
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.550
1xh9R69cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.542
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.538
1vebI05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.534
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.520
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.508
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.506
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.504
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.498
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.495
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.494
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.493
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.490
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.489
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.474
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.472
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.468
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.467
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440