sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1sr7 | MOF | Progesterone receptor |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1sr7 | MOF | Progesterone receptor | / | 1.000 | |
| 1p93 | DEX | Glucocorticoid receptor | / | 0.558 | |
| 1zuc | T98 | Progesterone receptor | / | 0.531 | |
| 4udc | DEX | Glucocorticoid receptor | / | 0.515 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.492 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.484 | |
| 1ya3 | STR | Mineralocorticoid receptor | / | 0.481 | |
| 1sqn | NDR | Progesterone receptor | / | 0.478 | |
| 4p6x | HCY | Glucocorticoid receptor | / | 0.472 | |
| 2w8y | 486 | Progesterone receptor | / | 0.453 | |
| 3zrb | ORC | Progesterone receptor | / | 0.449 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.449 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.448 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.447 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 2w8y | NDR | Progesterone receptor | / | 0.443 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.443 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.442 | |
| 4uda | DEX | Mineralocorticoid receptor | / | 0.441 |