Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
1sln | INH | Stromelysin-1 | 3.4.24.17 |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
1sln | INH | Stromelysin-1 | 3.4.24.17 | 1.000 | |
3ljg | EEF | Macrophage metalloelastase | 3.4.24.65 | 0.539 | |
1b8y | IN7 | Stromelysin-1 | 3.4.24.17 | 0.532 | |
1g05 | BBH | Stromelysin-1 | 3.4.24.17 | 0.510 | |
3tsk | QEG | Macrophage metalloelastase | 3.4.24.65 | 0.496 | |
4dpe | NGH | Stromelysin-1 | 3.4.24.17 | 0.496 | |
1hy7 | MBS | Stromelysin-1 | 3.4.24.17 | 0.489 | |
3kec | 3KE | Collagenase 3 | 3.4.24 | 0.486 | |
1caq | DPS | Stromelysin-1 | 3.4.24.17 | 0.479 | |
4gr3 | R45 | Macrophage metalloelastase | 3.4.24.65 | 0.479 | |
2wo8 | 077 | Macrophage metalloelastase | 3.4.24.65 | 0.476 | |
4gr8 | R4C | Macrophage metalloelastase | 3.4.24.65 | 0.476 | |
1d8f | SPI | Stromelysin-1 | 3.4.24.17 | 0.475 | |
1biw | S80 | Stromelysin-1 | 3.4.24.17 | 0.473 | |
1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.471 | |
2woa | 576 | Macrophage metalloelastase | 3.4.24.65 | 0.469 | |
3o2x | 3O2 | Collagenase 3 | 3.4.24 | 0.468 | |
1d7x | SPC | Stromelysin-1 | 3.4.24.17 | 0.467 | |
4ja1 | NGH | Stromelysin-1 | 3.4.24.17 | 0.467 | |
2ow1 | 7MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.466 | |
4gql | R47 | Macrophage metalloelastase | 3.4.24.65 | 0.464 | |
2ovx | 4MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.462 | |
1d8m | BBH | Stromelysin-1 | 3.4.24.17 | 0.459 | |
1g49 | 111 | Stromelysin-1 | 3.4.24.17 | 0.459 | |
3ts4 | EEG | Macrophage metalloelastase | 3.4.24.65 | 0.458 | |
1ciz | DPS | Stromelysin-1 | 3.4.24.17 | 0.455 | |
3kry | 3KR | Collagenase 3 | 3.4.24 | 0.454 | |
2hu6 | 37A | Macrophage metalloelastase | 3.4.24.65 | 0.452 | |
4guy | KLJ | Macrophage metalloelastase | 3.4.24.65 | 0.452 | |
2ovz | 5MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.451 | |
2wo9 | 068 | Macrophage metalloelastase | 3.4.24.65 | 0.451 | |
4a7b | 3W4 | Collagenase 3 | 3.4.24 | 0.451 | |
1c8t | TR1 | Stromelysin-1 | 3.4.24.17 | 0.450 | |
3lil | EEA | Macrophage metalloelastase | 3.4.24.65 | 0.449 | |
4gr0 | R4B | Macrophage metalloelastase | 3.4.24.65 | 0.449 | |
2ow0 | 6MR | Matrix metalloproteinase-9 | 3.4.24.35 | 0.447 | |
3oho | Z79 | Stromelysin-1 | 3.4.24.17 | 0.446 | |
3zxh | E41 | Collagenase 3 | 3.4.24 | 0.446 | |
2oxw | ILE_ALA_GLY | Macrophage metalloelastase | 3.4.24.65 | 0.445 | |
1bqo | N25 | Stromelysin-1 | 3.4.24.17 | 0.443 | |
1hv5 | RXP | Stromelysin-3 | 3.4.24 | 0.442 | |
1xuc | PB3 | Collagenase 3 | 3.4.24 | 0.442 | |
1ztq | 033 | Collagenase 3 | 3.4.24 | 0.440 | |
4i03 | L88 | Macrophage metalloelastase | 3.4.24.65 | 0.440 |