sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1skm	SAH	Modification methylase HhaI	2.1.1.37

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1skm	SAH	Modification methylase HhaI	2.1.1.37	1.000
2z6u	SAH	Modification methylase HhaI	2.1.1.37	0.647
9mht	SAH	Modification methylase HhaI	2.1.1.37	0.645
7mht	SAH	Modification methylase HhaI	2.1.1.37	0.635
5mht	SAH	Modification methylase HhaI	2.1.1.37	0.625
2zcj	SAH	Modification methylase HhaI	2.1.1.37	0.624
10mh	SAH	Modification methylase HhaI	2.1.1.37	0.621
2i9k	SAH	Modification methylase HhaI	2.1.1.37	0.613
1fjx	SAH	Modification methylase HhaI	2.1.1.37	0.611
8mht	SAH	Modification methylase HhaI	2.1.1.37	0.603
2uyh	SAH	Modification methylase HhaI	2.1.1.37	0.597
1mht	SAH	Modification methylase HhaI	2.1.1.37	0.592
2c7q	SAH	Modification methylase HhaI	2.1.1.37	0.590
4mht	SAH	Modification methylase HhaI	2.1.1.37	0.568
2hmy	SAM	Modification methylase HhaI	2.1.1.37	0.542
3qv2	SAH	5-cytosine DNA methyltransferase	/	0.456