sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1sep | BIO | Sepiapterin reductase | 1.1.1.153 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1sep | BIO | Sepiapterin reductase | 1.1.1.153 | 1.000 | |
| 1nas | ASE | Sepiapterin reductase | 1.1.1.153 | 0.749 | |
| 4j7u | YTZ | Sepiapterin reductase | 1.1.1.153 | 0.576 | |
| 4hwk | SFY | Sepiapterin reductase | 1.1.1.153 | 0.554 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.524 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.512 | |
| 3ix3 | OHN | Transcriptional activator protein LasR | / | 0.511 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.510 | |
| 3u2m | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.509 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.507 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.506 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.506 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.506 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.505 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.504 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.504 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.502 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.500 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.499 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.499 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.499 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.497 | |
| 3eks | CY9 | Actin-5C | / | 0.497 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.496 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.496 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.496 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.496 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.495 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.493 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.493 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.493 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.493 | |
| 4ira | FAD | 4-hydroxyphenylacetate 3-monooxygenase | / | 0.493 | |
| 1ppj | ANY | Cytochrome b | / | 0.492 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.492 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.492 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.492 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.492 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.492 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.492 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.491 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.491 | |
| 3eq6 | BCO | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.491 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.491 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.490 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.489 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.489 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.489 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.488 | |
| 3r1r | ATP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.488 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.487 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.487 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.487 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.487 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.486 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.486 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.486 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.486 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.486 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.485 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.485 | |
| 2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.485 | |
| 1r8b | ATP | CCA-adding enzyme | 2.7.7.72 | 0.484 | |
| 1vgr | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.484 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.484 | |
| 3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.484 | |
| 1u2r | SO1 | Elongation factor 2 | / | 0.483 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.483 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.483 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.483 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.482 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.482 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.482 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 3djf | BC3 | Purine nucleoside phosphorylase | / | 0.482 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.482 | |
| 3eku | CY9 | Actin-5C | / | 0.482 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.482 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.481 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.481 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.481 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.480 | |
| 1lke | DOG | Bilin-binding protein | / | 0.480 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 1rz1 | NAD | Phenol 2-hydroxylase component B | / | 0.479 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.479 | |
| 2ejz | SAH | Diphthine synthase | / | 0.479 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.479 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.478 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 2pch | SAH | Diphthine synthase | / | 0.478 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.478 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.478 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.478 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.478 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.478 | |
| 4cj4 | S3G | Integrase | / | 0.478 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.478 | |
| 1e2n | RCA | Thymidine kinase | / | 0.477 | |
| 2d81 | RB3 | Poly(3-hydroxybutyrate) depolymerase | / | 0.477 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.477 | |
| 4buv | 16I | Tankyrase-2 | 2.4.2.30 | 0.477 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.476 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.476 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.476 | |
| 4hh0 | FMN | AppA protein | / | 0.476 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.475 | |
| 1q19 | SSC | Carbapenam-3-carboxylate synthase | 6.3.3.6 | 0.475 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.475 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.475 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.475 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.475 | |
| 4ggz | BTN | Bll1558 protein | / | 0.475 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.474 | |
| 1wua | AP8 | Actin, alpha skeletal muscle | / | 0.474 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.474 | |
| 2x8e | X8E | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.474 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.474 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.474 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.474 | |
| 3uxh | UXH | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.474 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.474 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.474 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.473 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.473 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.473 | |
| 2e20 | B4P | Propionate kinase | / | 0.473 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.473 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.473 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.473 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.473 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.472 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.472 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.472 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.472 | |
| 1g8j | MGD | Arsenite oxidase subunit AioA | 1.20.9.1 | 0.471 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.471 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.471 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.471 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.471 | |
| 4nvk | 2NY | Peroxidase | / | 0.471 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.470 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.470 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.470 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.470 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.470 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.470 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.470 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.470 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.469 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.469 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.469 | |
| 1zdw | FLV | Prenyltransferase | / | 0.469 | |
| 2pca | SAH | Diphthine synthase | / | 0.469 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.469 | |
| 3b9l | AZZ | Serum albumin | / | 0.469 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3prs | RIT | Endothiapepsin | 3.4.23.22 | 0.469 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.469 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.469 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.469 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.469 | |
| 4ku7 | PCG | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.469 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.468 | |
| 1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.468 | |
| 1wng | SAH | Diphthine synthase | / | 0.468 | |
| 2cjp | VPR | Epoxide hydrolase | / | 0.468 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.468 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.468 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.468 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.468 | |
| 4ftr | 5HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.468 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.468 | |
| 1uhh | CZP | Aequorin-2 | / | 0.467 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.467 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.467 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.467 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.467 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.467 | |
| 3t7p | 7SP | Endothiapepsin | 3.4.23.22 | 0.467 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.467 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.467 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.467 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.467 | |
| 4kc1 | WS1 | Histo-blood group ABO system transferase | / | 0.467 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.467 | |
| 4xzn | NAP | Aldo-keto reductase family 1 member B10 | 1.1.1 | 0.467 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.466 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.466 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.466 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.466 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.466 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.466 | |
| 3dha | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.466 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.466 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.466 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.466 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.466 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.466 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.466 | |
| 1e64 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.465 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.465 | |
| 1fnc | FDA | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.465 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.465 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 3klb | FMN | Uncharacterized protein | / | 0.465 | |
| 3pgi | F41 | Endothiapepsin | 3.4.23.22 | 0.465 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.465 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.465 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.465 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.464 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.464 | |
| 2e08 | SAH | Diphthine synthase | / | 0.464 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.464 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.464 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.464 | |
| 2qcx | PF1 | Aminopyrimidine aminohydrolase | / | 0.464 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.464 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.464 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.464 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.464 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.464 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.464 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.464 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.464 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.463 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.463 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.463 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.463 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.463 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.463 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.463 | |
| 3c1o | NAP | Eugenol synthase | / | 0.463 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.463 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.463 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.463 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4l3q | 926 | Glucokinase | 2.7.1.2 | 0.463 | |
| 1e2j | THM | Thymidine kinase | / | 0.462 | |
| 1h65 | GDP | Translocase of chloroplast 34 | 3.6.5 | 0.462 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.462 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.462 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.462 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.462 | |
| 2zts | ADP | Uncharacterized protein | / | 0.462 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.462 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.462 | |
| 3tk0 | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.462 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.462 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.462 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.462 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.462 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.462 | |
| 3pwh | ZMA | Adenosine receptor A2a | / | 0.462 | |
| 1e82 | M90 | Endothiapepsin | 3.4.23.22 | 0.461 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.461 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2cbr | A80 | Cellular retinoic acid-binding protein 1 | / | 0.461 | |
| 2e16 | SAH | Diphthine synthase | / | 0.461 | |
| 2el0 | SAH | Diphthine synthase | / | 0.461 | |
| 2j7p | GNP | Signal recognition particle protein | / | 0.461 | |
| 2j7p | GNP | Signal recognition particle receptor FtsY | / | 0.461 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.461 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.461 | |
| 3t4h | MD5 | Alpha-ketoglutarate-dependent dioxygenase AlkB | 1.14.11.33 | 0.461 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 3v2u | ATP | Protein GAL3 | / | 0.461 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.461 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.461 | |
| 4koa | NDP | 1,5-anhydro-D-fructose reductase | 1.1.1.292 | 0.461 | |
| 4l4x | NDP | AmphI | / | 0.461 | |
| 1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.460 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.460 | |
| 1rz0 | FAD | Phenol 2-hydroxylase component B | / | 0.460 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.460 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 3rdo | BTN | Streptavidin | / | 0.460 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.460 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.460 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 4y4j | LNR | Endothiapepsin | 3.4.23.22 | 0.460 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.460 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.459 | |
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.459 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.459 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.459 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.459 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.459 | |
| 2avx | HTF | Regulatory protein SdiA | / | 0.459 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.459 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.459 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.459 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.459 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.459 | |
| 3zgl | 10E | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase | / | 0.459 | |
| 4avu | LDR | Tankyrase-2 | 2.4.2.30 | 0.459 | |
| 4je5 | PLP | Aromatic/aminoadipate aminotransferase 1 | 2.6.1.39 | 0.459 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.459 | |
| 4lh7 | 1X8 | DNA ligase | / | 0.459 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.459 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.459 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.458 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.458 | |
| 1wur | 8DG | GTP cyclohydrolase 1 | / | 0.458 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.458 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.458 | |
| 2b4y | APR | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.458 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.458 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.458 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.458 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3rdq | DTB | Streptavidin | / | 0.458 | |
| 4bqw | QNM | Egl nine homolog 1 | / | 0.458 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.458 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.458 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.458 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.458 | |
| 5dp2 | NAP | CurF | / | 0.458 | |
| 1esm | COA | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.457 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.457 | |
| 1x27 | ASP_ASP_TYR_VAL_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.457 | |
| 2e8h | SAH | Diphthine synthase | / | 0.457 | |
| 2e8q | SAH | Diphthine synthase | / | 0.457 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.457 | |
| 2egl | SAH | Diphthine synthase | / | 0.457 | |
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.457 | |
| 2fbw | CBE | Succinate dehydrogenase cytochrome b, large subunit | / | 0.457 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.457 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.457 | |
| 2qtg | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1 | 3.2.2.9 | 0.457 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.457 | |
| 2xvv | 9DN | Serum albumin | / | 0.457 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.457 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.457 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 3gey | P34 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.457 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.457 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.457 | |
| 4de3 | DN8 | Beta-lactamase | / | 0.457 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.457 | |
| 4e0i | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.457 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.457 | |
| 4ii4 | BYC | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.457 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.457 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.457 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.457 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.457 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.457 | |
| 1c4u | IH1 | Prothrombin | 3.4.21.5 | 0.456 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 1e80 | 0GQ | Endothiapepsin | 3.4.23.22 | 0.456 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.456 | |
| 1oqc | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.456 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.456 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.456 | |
| 2huq | SAH | Diphthine synthase | / | 0.456 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.456 | |
| 2owg | SAH | Diphthine synthase | / | 0.456 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.456 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.456 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.456 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.456 | |
| 3nhy | A7B | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.456 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.456 | |
| 4bhw | 01K | Histone acetyltransferase p300 | / | 0.456 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.456 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.456 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.456 | |
| 1h85 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.455 | |
| 1jkx | 138 | Phosphoribosylglycinamide formyltransferase | / | 0.455 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.455 | |
| 1ycf | FMN | Nitric oxide reductase | 1 | 0.455 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.455 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.455 | |
| 2bzs | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.455 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.455 | |
| 2e07 | SAH | Diphthine synthase | / | 0.455 | |
| 2emr | SAH | Diphthine synthase | / | 0.455 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.455 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.455 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.455 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.455 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.455 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.455 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.455 | |
| 4e2d | FMN | Dehydrogenase | / | 0.455 | |
| 4lcw | 1VY | Major histocompatibility complex class I-related gene protein | / | 0.455 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.455 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.455 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.454 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.454 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.454 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.454 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.454 | |
| 2hl2 | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.454 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.454 | |
| 2pcm | SAH | Diphthine synthase | / | 0.454 | |
| 2tys | PLT | Tryptophan synthase beta chain | 4.2.1.20 | 0.454 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.454 | |
| 2z50 | 028 | Geranylgeranyl pyrophosphate synthase | / | 0.454 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.454 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.454 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.454 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.454 | |
| 4jji | NAD | Alcohol dehydrogenase class-3 | / | 0.454 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.454 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.454 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.454 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.454 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.453 | |
| 1ppk | IVV | Penicillopepsin-1 | 3.4.23.20 | 0.453 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.453 | |
| 1w87 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.453 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2p6l | SAH | Diphthine synthase | / | 0.453 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.453 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.453 | |
| 2wmd | ZZ0 | NmrA-like family domain-containing protein 1 | / | 0.453 | |
| 2xvw | 9NR | Serum albumin | / | 0.453 | |
| 2zi6 | 3D1 | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3dle | GFA | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3gy9 | COA | GCN5-related N-acetyltransferase | / | 0.453 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.453 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.453 | |
| 3u5s | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.453 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4dru | 0LN | Genome polyprotein | 2.7.7.48 | 0.453 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.453 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.453 | |
| 4jdc | NAD | Probable pyrroline-5-carboxylate dehydrogenase RocA | / | 0.453 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1gvv | 0GM | Endothiapepsin | 3.4.23.22 | 0.452 | |
| 1r2j | FAD | FkbI | / | 0.452 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.452 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.452 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.452 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.452 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.452 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.452 | |
| 2ibw | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.452 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.452 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 2z6r | SAH | Diphthine synthase | / | 0.452 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.452 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.452 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.452 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.452 | |
| 3cvk | N34 | Genome polyprotein | 2.7.7.48 | 0.452 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.452 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.452 | |
| 3ogk | OGK | Coronatine-insensitive protein 1 | / | 0.452 | |
| 3upt | TPP | Transketolase | / | 0.452 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.452 | |
| 4gh2 | HK0 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4to0 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.452 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 4xvy | SAH | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.452 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.452 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.451 | |
| 1kf0 | ACP | Phosphoglycerate kinase 1 | 2.7.2.3 | 0.451 | |
| 1m9n | AMZ | Bifunctional purine biosynthesis protein PURH | 2.1.2.3 | 0.451 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.451 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.451 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1swt | BTN | Streptavidin | / | 0.451 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.451 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.451 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 2de4 | BPS | 2'-hydroxybiphenyl-2-sulfinate desulfinase | 3.13.1.3 | 0.451 | |
| 2dsg | SAH | Diphthine synthase | / | 0.451 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.451 | |
| 2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.451 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.451 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.451 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.451 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.451 | |
| 4bs4 | A64 | Tankyrase-2 | 2.4.2.30 | 0.451 | |
| 4buf | F36 | Tankyrase-2 | 2.4.2.30 | 0.451 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.451 | |
| 4cf1 | IY7 | Integrase | / | 0.451 | |
| 4ha6 | PXM | Pyridoxine 4-oxidase | / | 0.451 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.451 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.451 | |
| 1fml | RTL | Retinol dehydratase | / | 0.450 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.450 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.450 | |
| 1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.450 | |
| 1nw6 | SFG | Modification methylase RsrI | 2.1.1.72 | 0.450 | |
| 1pwu | GM6 | Lethal factor | 3.4.24.83 | 0.450 | |
| 1qv0 | CZH | Obelin | / | 0.450 | |
| 1s1v | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.450 | |
| 1vce | SAH | Diphthine synthase | / | 0.450 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2pbz | ATP | Uncharacterized protein | / | 0.450 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.450 | |
| 3l5t | 956 | Macrophage migration inhibitory factor | 5.3.2.1 | 0.450 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.450 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.450 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.450 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.450 | |
| 4bux | F35 | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.450 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.450 | |
| 4n1g | CEI | Obelin | / | 0.450 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.450 | |
| 5c4c | UPG | Histo-blood group ABO system transferase | / | 0.450 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.450 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.449 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1srj | NAB | Streptavidin | / | 0.449 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.449 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.449 | |
| 1v93 | FAD | Methylenetetrahydrofolate reductase | / | 0.449 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.449 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.449 | |
| 2eni | SAH | Diphthine synthase | / | 0.449 | |
| 2f6r | ACO | Bifunctional coenzyme A synthase | / | 0.449 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.449 | |
| 2jji | 0QS | Endothiapepsin | 3.4.23.22 | 0.449 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.449 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3i6r | J5Z | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.449 | |
| 3q1f | YPP | Beta-lactamase | / | 0.449 | |
| 3q2j | CKI | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.449 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.449 | |
| 4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.449 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.449 | |
| 5egh | PC | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 | / | 0.449 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.448 | |
| 1e7w | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.448 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.448 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.448 | |
| 1n5t | OAL | ActVA 6 protein | / | 0.448 | |
| 1nhg | TCL | Enoyl-ACP reductase | / | 0.448 | |
| 1svm | ATP | Large T antigen | 3.6.4 | 0.448 | |
| 2aqb | TL6 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.448 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.448 | |
| 2dxv | SAH | Diphthine synthase | / | 0.448 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2pk3 | GDD | GDP-6-deoxy-D-mannose reductase | / | 0.448 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2qmz | LDP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 3cne | FMN | Putative protease I | / | 0.448 | |
| 3ful | 52D | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.448 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.448 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.448 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.448 | |
| 3ndj | JHZ | Methyltransferase | / | 0.448 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.448 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.448 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.448 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.448 | |
| 4isz | GAV | tRNA-splicing ligase RtcB | 6.5.1 | 0.448 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.448 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.448 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.448 | |
| 4yak | COA | Acyl-CoA synthetase (NDP forming) | / | 0.448 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.448 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.447 | |
| 1coy | AND | Cholesterol oxidase | 1.1.3.6 | 0.447 | |
| 1ef9 | 2CP | Methylmalonyl-CoA decarboxylase | 4.1.1.41 | 0.447 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
| 1gaw | FAD | Ferredoxin | / | 0.447 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.447 | |
| 1p5r | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.447 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.447 | |
| 1til | ATP | Anti-sigma F factor | / | 0.447 | |
| 2b51 | UTP | RNA editing complex protein MP57 | / | 0.447 | |
| 2bbw | GP5 | Adenylate kinase 4, mitochondrial | / | 0.447 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.447 | |
| 2ehl | SAH | Diphthine synthase | / | 0.447 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.447 | |
| 2owf | SAH | Diphthine synthase | / | 0.447 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.447 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2xvu | 9DN | Serum albumin | / | 0.447 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.447 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.447 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.447 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.447 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.447 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.447 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.447 | |
| 3pi0 | F91 | Endothiapepsin | 3.4.23.22 | 0.447 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.447 | |
| 3s1a | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.447 | |
| 3u2l | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.447 | |
| 3vi7 | CBD | Hematopoietic prostaglandin D synthase | / | 0.447 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.447 | |
| 4c73 | TLH | 3-oxoacyl-ACP synthase | / | 0.447 | |
| 4cgj | NZL | Integrase | / | 0.447 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.447 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.447 | |
| 5cuq | NSC | Genome polyprotein | / | 0.447 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.447 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.447 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.446 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.446 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.446 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.446 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.446 | |
| 2ejk | SAH | Diphthine synthase | / | 0.446 | |
| 2emu | SAH | Diphthine synthase | / | 0.446 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.446 | |
| 2owu | SAH | Diphthine synthase | / | 0.446 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.446 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.446 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.446 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.446 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.446 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.446 | |
| 3dz7 | O8M | S-adenosylmethionine decarboxylase proenzyme | 4.1.1.50 | 0.446 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.446 | |
| 3ha3 | SAH | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.446 | |
| 3hy3 | 10F | 5-formyltetrahydrofolate cyclo-ligase | 6.3.3.2 | 0.446 | |
| 3mte | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.446 | |
| 3pmu | F7L | Endothiapepsin | 3.4.23.22 | 0.446 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 3thy | ADP | DNA mismatch repair protein Msh2 | / | 0.446 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.446 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.446 | |
| 4bao | MVF | Prothrombin | 3.4.21.5 | 0.446 | |
| 4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.446 | |
| 4fhp | UTP | Terminal uridylyltransferase cid1 | / | 0.446 | |
| 4gd9 | BTN | Streptavidin | / | 0.446 | |
| 4la7 | A1O | Abscisic acid receptor PYL2 | / | 0.446 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.446 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.445 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.445 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.445 | |
| 1m2o | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.445 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.445 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.445 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 2dek | SAH | Diphthine synthase | / | 0.445 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.445 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.445 | |
| 2ilu | NDP | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.445 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.445 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.445 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.445 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.445 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.445 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.445 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.445 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.445 | |
| 3uaw | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.445 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.445 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.445 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.445 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.445 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
| 4mfe | BTN | Pyruvate carboxylase | / | 0.445 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.445 | |
| 1ej3 | CZH | Aequorin-2 | / | 0.444 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.444 | |
| 1i2l | DCS | Aminodeoxychorismate lyase | 4.1.3.38 | 0.444 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 1q12 | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.444 | |
| 1qgy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 1qm5 | PLP | Maltodextrin phosphorylase | 2.4.1.1 | 0.444 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.444 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.444 | |
| 1wl4 | COA | Acetyl-CoA acetyltransferase, cytosolic | 2.3.1.9 | 0.444 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.444 | |
| 1yrx | FMN | AppA protein | / | 0.444 | |
| 2a4x | BLM | Mitomycin-binding protein | / | 0.444 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.444 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.444 | |
| 2g1m | 4HG | Egl nine homolog 1 | / | 0.444 | |
| 2iby | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.444 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.444 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.444 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.444 | |
| 3f8w | ADN | Purine nucleoside phosphorylase | / | 0.444 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.444 | |
| 3p9t | TCL | Repressor | / | 0.444 | |
| 3pld | F90 | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 4cfa | WOP | Integrase | / | 0.444 | |
| 4dne | DTB | Streptavidin | / | 0.444 | |
| 4e0h | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.444 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.444 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.444 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4jic | FMN | GTN Reductase | / | 0.444 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.444 | |
| 4loc | BTN | Pyruvate carboxylase | / | 0.444 | |
| 4lvg | 20O | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.444 | |
| 1eyq | NAR | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.443 | |
| 1f3e | DPZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.443 | |
| 1hrv | SDZ | Genome polyprotein | / | 0.443 | |
| 1i05 | LTL | Major urinary protein 6 | / | 0.443 | |
| 1jzs | MRC | Isoleucine--tRNA ligase | 6.1.1.5 | 0.443 | |
| 1osv | CHC | Bile acid receptor | / | 0.443 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.443 | |
| 1xvv | CCQ | L-carnitine CoA-transferase | / | 0.443 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.443 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.443 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.443 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 2uyw | BTN | Avd protein | / | 0.443 | |
| 2w02 | ATP | AcsD | / | 0.443 | |
| 2z4j | DHT | Androgen receptor | / | 0.443 | |
| 3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.443 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.443 | |
| 3bsy | ACO | UDP-N-acetylbacillosamine N-acetyltransferase | 2.3.1.203 | 0.443 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3cx4 | ADP | Glycogen synthase | 2.4.1.21 | 0.443 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.443 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.443 | |
| 3ei8 | PL5 | LL-diaminopimelate aminotransferase, chloroplastic | / | 0.443 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.443 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.443 | |
| 3ha7 | B32 | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.443 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.443 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.443 | |
| 3r7c | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.443 | |
| 3rzp | PRF | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.443 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.443 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 4bqy | FNT | Egl nine homolog 1 | / | 0.443 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.443 | |
| 4ck2 | NVU | Integrase | / | 0.443 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.443 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.443 | |
| 4hki | FLN | Tankyrase-2 | 2.4.2.30 | 0.443 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.443 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.443 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.443 | |
| 4p13 | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.443 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.443 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.443 | |
| 4ubf | ADP | Kinesin-like protein KIF2C | / | 0.443 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.443 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.443 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.443 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.443 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.443 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.442 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1kt7 | RTL | Retinol-binding protein 4 | / | 0.442 | |
| 1n0u | SO1 | Elongation factor 2 | / | 0.442 | |
| 1pxx | DIF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.442 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.442 | |
| 1xp8 | AGS | Protein RecA | / | 0.442 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.442 | |
| 1z2n | ADP | Inositol-tetrakisphosphate 1-kinase | 2.7.1.134 | 0.442 | |
| 2bxm | IMN | Serum albumin | / | 0.442 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.442 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.442 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.442 | |
| 3bus | SAH | Demethylrebeccamycin-D-glucose O-methyltransferase | / | 0.442 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.442 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 3o9p | MHI | Periplasmic murein peptide-binding protein | / | 0.442 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.442 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.442 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.442 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.442 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.442 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4cfc | 7NV | Integrase | / | 0.442 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.442 | |
| 4l32 | 1VF | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4rrh | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.442 | |
| 4tlc | AGS | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.442 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.442 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 1amo | FAD | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.441 | |
| 1dtp | APU | Diphtheria toxin | / | 0.441 | |
| 1efa | NPF | Lactose operon repressor | / | 0.441 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.441 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1i9h | BNI | Streptavidin | / | 0.441 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1n5s | ADL | ActVA 6 protein | / | 0.441 | |
| 1nt1 | T76 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.441 | |
| 1pr5 | TBN | Purine nucleoside phosphorylase DeoD-type | / | 0.441 | |
| 1pz0 | NAP | Protein IolS | 1.1.1 | 0.441 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.441 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.441 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.441 | |
| 2brn | DF1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2ele | SAH | Diphthine synthase | / | 0.441 | |
| 2en5 | SAH | Diphthine synthase | / | 0.441 | |
| 2hxd | DUP | dCTP deaminase, dUMP-forming | 3.5.4.30 | 0.441 | |
| 2jfz | 003 | Glutamate racemase | / | 0.441 | |
| 2lbv | EB4 | Extracellular fatty acid-binding protein | / | 0.441 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.441 | |
| 2pci | SAH | Diphthine synthase | / | 0.441 | |
| 2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2ydi | YDI | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 3a6q | FMN | FMN-binding protein | / | 0.441 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.441 | |
| 3bw2 | FMN | Putative 2-nitropropane dioxygenase | / | 0.441 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.441 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.441 | |
| 3dok | GWJ | Pol protein | / | 0.441 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.441 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.441 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.441 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.441 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.441 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.441 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.441 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.441 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.441 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.441 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.441 | |
| 4gh1 | 0WX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.441 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.441 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.441 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.441 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.441 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1bjk | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.440 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1gvw | 0EM | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.440 | |
| 1ky2 | GNP | GTP-binding protein YPT7 | / | 0.440 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.440 | |
| 1qgz | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.440 | |
| 1yci | NDF | Hypoxia-inducible factor 1-alpha inhibitor | 1.14.11.30 | 0.440 | |
| 2bac | FAD | Putative aminooxidase | / | 0.440 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2e8w | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 2gz8 | F3F | Orf1a polyprotein | / | 0.440 | |
| 2hg1 | N5O | Endoplasmin | / | 0.440 | |
| 2rtn | IMI | Streptavidin | / | 0.440 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 2zr9 | DTP | Protein RecA | / | 0.440 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.440 | |
| 3dt2 | GTP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.440 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.440 | |
| 3gus | N11 | Glutathione S-transferase P | 2.5.1.18 | 0.440 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.440 | |
| 3pbz | F02 | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.440 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.440 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 4a7b | 3W5 | Collagenase 3 | 3.4.24 | 0.440 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4cgi | NZL | Integrase | / | 0.440 | |
| 4e32 | DWN | Methyltransferase | / | 0.440 | |
| 4iah | 1DX | Alr2278 protein | / | 0.440 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.440 | |
| 4olf | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.440 | |
| 4qxa | GTP | Ras-related protein Rab-9A | / | 0.440 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.440 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.440 |