sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 1.000 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.713 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.703 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.615 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.563 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.519 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.508 | |
| 1a9s | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.506 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.506 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.505 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.503 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.503 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.502 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.499 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.498 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.497 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.497 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.497 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.496 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.496 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.495 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.495 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.493 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.492 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.491 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.491 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.491 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.491 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.490 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.486 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.486 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.485 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.484 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.484 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.483 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.483 | |
| 1b8n | IMG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.482 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.482 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.482 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.481 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.481 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.481 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.480 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.480 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.479 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.479 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.478 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.478 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.478 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.477 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.477 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.477 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.477 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 2ejz | SAH | Diphthine synthase | / | 0.475 | |
| 2emu | SAH | Diphthine synthase | / | 0.475 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.475 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.475 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.473 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.473 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.472 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.472 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.472 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.472 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.471 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.471 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.471 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.471 | |
| 2emr | SAH | Diphthine synthase | / | 0.471 | |
| 2rgx | AP5 | Adenylate kinase | / | 0.471 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.471 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.471 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.471 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.471 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.470 | |
| 2pch | SAH | Diphthine synthase | / | 0.470 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.470 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.470 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.469 | |
| 3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.469 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.469 | |
| 5a3c | NAD | SIR2 family protein | / | 0.469 | |
| 2eh5 | SAH | Diphthine synthase | / | 0.468 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.468 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.468 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.468 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.468 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.468 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.468 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.468 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.467 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.467 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.467 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.467 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.466 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.466 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.465 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.465 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.465 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.465 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.465 | |
| 4l17 | DNQ | Glutamate receptor 2 | / | 0.465 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.465 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.464 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.464 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.464 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.463 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.463 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.463 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 4jic | FMN | GTN Reductase | / | 0.463 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.463 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.462 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.462 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.462 | |
| 1osv | CHC | Bile acid receptor | / | 0.462 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.462 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.462 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.462 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.462 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.462 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.461 | |
| 2ejk | SAH | Diphthine synthase | / | 0.461 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.461 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.461 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.461 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.461 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.461 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.461 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.461 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.460 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.460 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 2fb3 | 5AD | GTP 3',8-cyclase | 4.1.99.18 | 0.460 | |
| 2gna | GDU | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.460 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.460 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.460 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.460 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.460 | |
| 4ple | CPS | Nuclear receptor subfamily 5 group A member 2 | / | 0.460 | |
| 1aj2 | 2PH | Dihydropteroate synthase | / | 0.459 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.459 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.459 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.459 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.459 | |
| 3i6i | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.459 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.459 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.459 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.459 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.459 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.459 | |
| 1a9p | 9DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.458 | |
| 1w7h | 3IP | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.458 | |
| 2hux | SAH | Diphthine synthase | / | 0.458 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.458 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.458 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.458 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.458 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.458 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 1m9j | CLW | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.457 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.457 | |
| 2p5c | SAH | Diphthine synthase | / | 0.457 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.457 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.457 | |
| 3eej | 53R | Uncharacterized protein | / | 0.457 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.457 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.457 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.456 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.456 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.456 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.456 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.456 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 1yvf | PH7 | Polyprotein | / | 0.456 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.456 | |
| 2e08 | SAH | Diphthine synthase | / | 0.456 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.456 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.456 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.456 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.456 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.456 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.456 | |
| 3up0 | D7S | aceDAF-12 | / | 0.456 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.456 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.456 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4jl5 | ADP | Adenylate kinase | / | 0.456 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.456 | |
| 1dtp | APU | Diphtheria toxin | / | 0.455 | |
| 1m9r | INE | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.455 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.455 | |
| 2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.455 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.455 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3gnv | XNZ | Genome polyprotein | 2.7.7.48 | 0.455 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.455 | |
| 3tqa | NDP | Dihydrofolate reductase | / | 0.455 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.455 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.454 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.454 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.454 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.454 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.454 | |
| 2v1a | FMN | NPH1-1 | / | 0.454 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.454 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.454 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.454 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.454 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.454 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.454 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.454 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.454 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.454 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.453 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.453 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.453 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.453 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.453 | |
| 3b9l | AZZ | Serum albumin | / | 0.453 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.453 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.453 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.453 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.453 | |
| 4lxm | 1YU | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.453 | |
| 1bpj | UMP | Thymidylate synthase | / | 0.452 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.452 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.452 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.452 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.452 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.452 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.452 | |
| 2egb | SAH | Diphthine synthase | / | 0.452 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.452 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.452 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.452 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.452 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.452 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.452 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.452 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.452 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.452 | |
| 4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.452 | |
| 1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.451 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.451 | |
| 1til | ATP | Anti-sigma F factor | / | 0.451 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 2e8h | SAH | Diphthine synthase | / | 0.451 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.451 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.451 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.451 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.451 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.451 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.451 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.451 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.451 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.450 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.450 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.450 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1ohh | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.450 | |
| 1ohh | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.450 | |
| 1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.450 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.450 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.450 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.450 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.450 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.450 | |
| 2qtv | GNP | Small COPII coat GTPase SAR1 | 3.6.5 | 0.450 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.450 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.450 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.450 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.450 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.450 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.450 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 4e2b | FMN | Dehydrogenase | / | 0.450 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.450 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.449 | |
| 1c7o | PPG | Hemolysin | / | 0.449 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.449 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.449 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.449 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.449 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 2owg | SAH | Diphthine synthase | / | 0.449 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.449 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.449 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.449 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.449 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.449 | |
| 4dja | FAD | (6-4) photolyase | / | 0.449 | |
| 4e2d | FMN | Dehydrogenase | / | 0.449 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.449 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.448 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 1m9k | 7NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.448 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.448 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.448 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.448 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 1wng | SAH | Diphthine synthase | / | 0.448 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.448 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 2egs | SAH | Diphthine synthase | / | 0.448 | |
| 2g28 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 2r97 | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.448 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.448 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.448 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.448 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.448 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.448 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.448 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.448 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.448 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.448 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.448 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4l4x | NDP | AmphI | / | 0.448 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.448 | |
| 4zzj | CNA | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.448 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.447 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.447 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.447 | |
| 1tsx | UMP | Thymidylate synthase | / | 0.447 | |
| 1vce | SAH | Diphthine synthase | / | 0.447 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.447 | |
| 2egl | SAH | Diphthine synthase | / | 0.447 | |
| 2eld | SAH | Diphthine synthase | / | 0.447 | |
| 2huv | SAH | Diphthine synthase | / | 0.447 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.447 | |
| 3hky | IX6 | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.447 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.447 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.447 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.447 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.447 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.446 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.446 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1g28 | FMN | PHY3 | / | 0.446 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2dv7 | SAH | Diphthine synthase | / | 0.446 | |
| 2dxv | SAH | Diphthine synthase | / | 0.446 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.446 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.446 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.446 | |
| 2r59 | PH0 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.446 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.446 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3ipk | PMS | Surface protein adhesin | / | 0.446 | |
| 3p5p | A3C | Taxadiene synthase | 4.2.3.17 | 0.446 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.446 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.446 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.446 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.446 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.446 | |
| 4qys | PLR | Tryptophan synthase beta chain 2 | 4.2.1.20 | 0.446 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.446 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.445 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 2ehl | SAH | Diphthine synthase | / | 0.445 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.445 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.445 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.445 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.445 | |
| 3exf | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.445 | |
| 3i6q | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.445 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.445 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.445 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.445 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.445 | |
| 4qbi | AP5 | Adenylate kinase | / | 0.445 | |
| 5a3b | APR | SIR2 family protein | / | 0.445 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.444 | |
| 1ddu | DDU | Thymidylate synthase | / | 0.444 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 2cjp | VPR | Epoxide hydrolase | / | 0.444 | |
| 2dxw | SAH | Diphthine synthase | / | 0.444 | |
| 2eeq | SAH | Diphthine synthase | / | 0.444 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.444 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.444 | |
| 2oo7 | AP5 | Adenylate kinase | / | 0.444 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.444 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.444 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.444 | |
| 3clu | FAD | Electron transfer flavoprotein subunit alpha | / | 0.444 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.444 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.444 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.444 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.444 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.444 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.444 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.444 | |
| 4lrr | CF9 | Thymidylate synthase | / | 0.444 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.444 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.444 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.444 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.444 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.443 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.443 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 1zdw | FLV | Prenyltransferase | / | 0.443 | |
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.443 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.443 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.443 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.443 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 2jj8 | AZZ | Deoxynucleoside kinase | / | 0.443 | |
| 2pcg | SAH | Diphthine synthase | / | 0.443 | |
| 2pcm | SAH | Diphthine synthase | / | 0.443 | |
| 2v0u | FMN | NPH1-1 | / | 0.443 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.443 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.443 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.443 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.443 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.443 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.443 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.442 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.442 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2owv | SAH | Diphthine synthase | / | 0.442 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.442 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.442 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.442 | |
| 3eku | CY9 | Actin-5C | / | 0.442 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.442 | |
| 3vi7 | CBD | Hematopoietic prostaglandin D synthase | / | 0.442 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.442 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.442 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.442 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.442 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4qbg | AP5 | Adenylate kinase | / | 0.442 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.442 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.441 | |
| 1nlm | UD1 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | / | 0.441 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.441 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.441 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.441 | |
| 2p6d | SAH | Diphthine synthase | / | 0.441 | |
| 2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.441 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.441 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.441 | |
| 4b0q | GMF | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4b67 | NAP | L-ornithine N(5)-monooxygenase | / | 0.441 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4g1c | CNA | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.441 | |
| 4j16 | NAP | NAD(P) transhydrogenase subunit beta | / | 0.441 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.441 | |
| 4ktf | 1TM | Cytochrome P450 | / | 0.441 | |
| 4mkh | AP5 | Adenylate kinase | / | 0.441 | |
| 4uxq | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.441 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.441 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.440 | |
| 1qnf | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 1rz0 | FAD | Phenol 2-hydroxylase component B | / | 0.440 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.440 | |
| 1u2r | SO1 | Elongation factor 2 | / | 0.440 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.440 | |
| 2j09 | FMN | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.440 | |
| 2p9d | SAH | Diphthine synthase | / | 0.440 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.440 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.440 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.440 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.440 | |
| 3i25 | MV7 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.440 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.440 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.440 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.440 | |
| 4l8u | 9AZ | Serum albumin | / | 0.440 | |
| 4ol0 | GTP | GTP-binding nuclear protein Ran | / | 0.440 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.440 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.440 | |
| 4uga | Q05 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.440 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.440 |