sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 1.000 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.536 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.512 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.512 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.511 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.509 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.508 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.507 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.507 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.505 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.505 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.504 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.503 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.501 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.500 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.500 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.498 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.495 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.494 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.493 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.492 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.492 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.491 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.489 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.489 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.488 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.488 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.487 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.486 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.486 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.486 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.486 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.485 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.485 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.484 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.484 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.484 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.484 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.484 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.483 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.483 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.482 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.482 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.482 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.481 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.481 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.481 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.481 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.480 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.479 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.479 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.479 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.479 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.479 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.478 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.478 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.478 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.478 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.477 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.476 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.476 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.475 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.475 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.475 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.474 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.474 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.474 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.474 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.474 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.473 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.473 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.473 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.473 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.473 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.472 | |
| 1r2j | FAD | FkbI | / | 0.472 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.472 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.471 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.471 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.471 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.471 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.471 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.471 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.471 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.471 | |
| 1ci7 | UMP | Thymidylate synthase | 2.1.1.45 | 0.470 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.470 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.470 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.470 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.470 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.470 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.469 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.469 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.469 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.469 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.468 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.468 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.468 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.467 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.467 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.467 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.466 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.466 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.465 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.465 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.465 | |
| 4xiv | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.465 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.464 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.464 | |
| 3d7t | STU | Tyrosine-protein kinase CSK | / | 0.464 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.464 | |
| 3up0 | D7S | aceDAF-12 | / | 0.464 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.464 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.463 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.463 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.463 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.462 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.462 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.462 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.462 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.462 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.462 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3r34 | COA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.462 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.462 | |
| 4gg5 | 0J3 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.462 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.461 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.461 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.461 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 3zux | TCH | Transporter | / | 0.461 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.461 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.460 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1p93 | DEX | Glucocorticoid receptor | / | 0.460 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.460 | |
| 1rby | KEU | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.460 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.460 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.460 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.460 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.460 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.460 | |
| 3dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.460 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 3wsb | RWZ | Farnesyltransferase, putative | / | 0.460 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.460 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.460 | |
| 4l9q | 9TP | Serum albumin | / | 0.460 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.459 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.459 | |
| 2y8q | ADP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.459 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 4oal | 245 | Cytokinin dehydrogenase 4 | / | 0.459 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.458 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.458 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.458 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.458 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.458 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.457 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.457 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.457 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.457 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.457 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.457 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.457 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.456 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.456 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.456 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1u8f | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.456 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.456 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.456 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 3qly | 55V | Uncharacterized protein | / | 0.456 | |
| 3r3c | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.456 | |
| 3r5z | F42 | Uncharacterized protein | / | 0.456 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.456 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.456 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.456 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.456 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.456 | |
| 1gqt | ACP | Ribokinase | / | 0.455 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.455 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.455 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.455 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.455 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.455 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
| 3up3 | XCA | aceDAF-12 | / | 0.455 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.455 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.455 | |
| 4pd6 | URI | Nucleoside permease | / | 0.455 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.455 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.455 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1zdw | FLV | Prenyltransferase | / | 0.454 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.454 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.454 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.454 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.454 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.454 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.454 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.454 | |
| 4c4j | X21 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.454 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.453 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.453 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.453 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.453 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.453 | |
| 4a9e | 3PF | Bromodomain-containing protein 2 | / | 0.453 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.453 | |
| 4egn | TWO | Cytochrome P450 | / | 0.453 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1iid | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.452 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.452 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 2j0m | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.452 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.452 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.452 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.452 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.452 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.452 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.452 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.452 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.452 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.452 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.452 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.452 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.451 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.451 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2zdu | 446 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.451 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.451 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.451 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.451 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.451 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.451 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.451 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.451 | |
| 4l98 | LRG | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 4neu | Q1A | Receptor-interacting serine/threonine-protein kinase 1 | 2.7.11.1 | 0.451 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.450 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.450 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.450 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.450 | |
| 2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.450 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.450 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.450 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.450 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.450 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.450 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.450 | |
| 3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.450 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.450 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.450 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1ha3 | MAU | Elongation factor Tu-A | / | 0.449 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.449 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 3h0s | B38 | Acetyl-CoA carboxylase | / | 0.449 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3w16 | P9J | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.449 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.449 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.449 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.449 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.449 | |
| 4l8u | 9AZ | Serum albumin | / | 0.449 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1cde | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.448 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.448 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.448 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.448 | |
| 1py5 | PY1 | TGF-beta receptor type-1 | 2.7.11.30 | 0.448 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.448 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.448 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.448 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.448 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.448 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.448 | |
| 3wec | AUI | Cytochrome P450 | / | 0.448 | |
| 3zhb | NAP | Putative dehydrogenase | / | 0.448 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.448 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.448 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.448 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4fox | UMP | Thymidylate synthase ThyA | / | 0.448 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.448 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.448 | |
| 4gj2 | 0XH | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.448 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.448 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.448 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.448 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.448 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.447 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.447 | |
| 1heu | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.447 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.447 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.447 | |
| 2ay3 | MPP | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.447 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.447 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.447 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.447 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.447 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.447 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.447 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.447 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3kga | LX9 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.447 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.447 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.447 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.447 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 5csh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1k6v | XN2 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1rx5 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 2bxm | IMN | Serum albumin | / | 0.446 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.446 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.446 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.446 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.446 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.446 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.446 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.446 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.446 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.446 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.446 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.446 | |
| 1ci7 | CB3 | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1jut | LYD | Thymidylate synthase | / | 0.445 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 1z0a | GDP | Ras-related protein Rab-2A | / | 0.445 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.445 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.445 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.445 | |
| 3lu8 | IQX | Serum albumin | / | 0.445 | |
| 3mnp | DEX | Glucocorticoid receptor | / | 0.445 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.445 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.445 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.445 | |
| 4hne | ADP | Phosphatidylinositol 4-kinase type 2-alpha | / | 0.445 | |
| 4ijp | 1EH | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.445 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.445 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.444 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.444 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.444 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.444 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
| 2w1g | L0G | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 2x4f | 16X | Myosin light chain kinase family member 4 | 2.7.11.1 | 0.444 | |
| 2xp2 | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.444 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.444 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 3cge | NDP | Coenzyme A disulfide reductase | / | 0.444 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3eld | SFG | Methyltransferase | / | 0.444 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3iqf | E4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.444 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 3qpv | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.444 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.444 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.444 | |
| 4h0x | NAD | Iota toxin component Ia | / | 0.444 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.444 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.444 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.443 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.443 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.443 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.443 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.443 | |
| 1xl2 | 189 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1xny | BTN | Propionyl-CoA carboxylase complex B subunit | / | 0.443 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2bfy | H1N | Aurora kinase B-A | 2.7.11.1 | 0.443 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.443 | |
| 2qhn | 582 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2w1f | L0F | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.443 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.443 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.443 | |
| 4g48 | PZB | Mycocyclosin synthase | 1.14.21.9 | 0.443 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.443 | |
| 4z0h | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic | 1.2.1.12 | 0.443 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.442 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.442 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.442 | |
| 1tvo | FRZ | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.442 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.442 | |
| 1zmd | NAI | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.442 | |
| 2b03 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.442 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 2fto | TMP | Thymidylate synthase | / | 0.442 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 2izu | P01 | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.442 | |
| 2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.442 | |
| 2vnh | FAD | NADPH:ferredoxin reductase | / | 0.442 | |
| 2yk2 | YJX | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3oc1 | BMU | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.442 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.442 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.442 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.442 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.442 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.442 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.442 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 4gyi | ADP | Uncharacterized protein | / | 0.442 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.442 | |
| 4k11 | 0J9 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.442 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.442 | |
| 4u7w | NDP | MxaA | / | 0.442 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 1y57 | MPZ | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.441 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 2jko | BIJ | Focal adhesion kinase 1 | 2.7.10.2 | 0.441 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 2xir | 00J | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.441 | |
| 2y3s | TIR | TamL | / | 0.441 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3bej | MUF | Bile acid receptor | / | 0.441 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.441 | |
| 3gob | HXX | DdmC | / | 0.441 | |
| 3h0a | D30 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.441 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.441 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.441 | |
| 3qj5 | 022 | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.441 | |
| 3zuy | TCH | Transporter | / | 0.441 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4bfm | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.441 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.441 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.441 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.441 | |
| 4rqv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.441 | |
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.440 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.440 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.440 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2cmw | OLP | Casein kinase I isoform gamma-1 | 2.7.11.1 | 0.440 | |
| 2ijm | ATP | Focal adhesion kinase 1 | 2.7.10.2 | 0.440 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 2v7a | 627 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.440 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.440 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3t2y | FAD | Sulfide-quinone reductase | / | 0.440 | |
| 3u5s | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.440 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.440 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.440 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.440 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.440 | |
| 4ix6 | ADP | Uncharacterized protein | / | 0.440 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.440 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.440 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.440 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.440 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.440 |