sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1s3z	COA	Aminoglycoside N(6')-acetyltransferase type 1

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1s3z	COA	Aminoglycoside N(6')-acetyltransferase type 1	/	1.000
2vbq	BSJ	Aminoglycoside N(6')-acetyltransferase type 1	/	0.681
1s60	COA	Aminoglycoside N(6')-acetyltransferase type 1	/	0.578
1s5k	COA	Aminoglycoside N(6')-acetyltransferase type 1	/	0.575
4lx9	ACO	N-alpha-acetyltransferase	2.3.1	0.518
2cnt	COA	Ribosomal-protein-alanine acetyltransferase	/	0.461
2y0m	ACO	Histone acetyltransferase KAT8	/	0.461
3pgp	ACO	Uncharacterized protein	/	0.458
4jwp	ACO	GCN5-related N-acetyltransferase	/	0.453
4jxr	ACO	Acetyltransferase	/	0.450
2cns	ACO	Ribosomal-protein-alanine acetyltransferase	/	0.447
4kvm	SER_ALA_SER_GLU_1XE	N-terminal acetyltransferase A complex catalytic subunit ard1	2.3.1.88	0.446
4qvt	ACO	Acetyltransferase YpeA	2.3.1	0.445
2ifa	FMN	Uncharacterized protein	/	0.443
4oae	CLM	Uncharacterized protein	/	0.443