Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1s1w | UC1 | Gag-Pol polyprotein | 2.7.7.49 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1s1w | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 1.000 | |
| 1tl1 | H18 | Gag-Pol polyprotein | 2.7.7.49 | 0.773 | |
| 2opq | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.708 | |
| 1tkt | H12 | Gag-Pol polyprotein | 2.7.7.49 | 0.707 | |
| 1rev | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.695 | |
| 1tkz | H16 | Gag-Pol polyprotein | 2.7.7.49 | 0.685 | |
| 1tl3 | H20 | Gag-Pol polyprotein | 2.7.7.49 | 0.656 | |
| 1ikw | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.654 | |
| 1rt4 | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.645 | |
| 3i0r | RT3 | Gag-Pol polyprotein | 2.7.7.49 | 0.638 | |
| 1hnv | TBO | Gag-Pol polyprotein | 2.7.7.49 | 0.631 | |
| 2vg5 | NNC | Gag-Pol polyprotein | 2.7.7.49 | 0.630 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.628 | |
| 2vg7 | NNI | Gag-Pol polyprotein | 2.7.7.49 | 0.622 | |
| 3mee | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.621 | |
| 1ikx | PNU | Gag-Pol polyprotein | 2.7.7.49 | 0.615 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.613 | |
| 1rt5 | UC2 | Gag-Pol polyprotein | 2.7.7.49 | 0.612 | |
| 2rf2 | MRX | Gag-Pol polyprotein | 2.7.7.49 | 0.610 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.607 | |
| 3meg | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.605 | |
| 4ko0 | JLJ | Gag-Pol polyprotein | 2.7.7.49 | 0.605 | |
| 1c1b | GCA | Gag-Pol polyprotein | 2.7.7.49 | 0.599 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.595 | |
| 1hni | AAA | Gag-Pol polyprotein | 2.7.7.49 | 0.593 | |
| 3i0s | RT7 | Gag-Pol polyprotein | 2.7.7.49 | 0.592 | |
| 1rt2 | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.591 | |
| 4i2p | G73 | Gag-Pol polyprotein | 2.7.7.49 | 0.591 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.588 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.586 | |
| 1ikv | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.585 | |
| 1eet | BFU | Gag-Pol polyprotein | 2.7.7.49 | 0.584 | |
| 4id5 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.584 | |
| 1tkx | GWB | Gag-Pol polyprotein | 2.7.7.49 | 0.580 | |
| 4ig3 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.580 | |
| 1s9e | ADB | Gag-Pol polyprotein | 2.7.7.49 | 0.576 | |
| 4kko | 1RE | Gag-Pol polyprotein | 2.7.7.49 | 0.576 | |
| 4g1q | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.575 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.574 | |
| 4i7f | NVE | Gag-Pol polyprotein | 2.7.7.49 | 0.572 | |
| 4ifv | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.569 | |
| 1jlq | SBN | Gag-Pol polyprotein | 2.7.7.49 | 0.567 | |
| 2ops | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.564 | |
| 1fk9 | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.562 | |
| 3ffi | 3OB | Gag-Pol polyprotein | 2.7.7.49 | 0.562 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.562 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.561 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.561 | |
| 3med | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.556 | |
| 1iky | MSD | Gag-Pol polyprotein | 2.7.7.49 | 0.555 | |
| 1jlg | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.554 | |
| 5cyq | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.552 | |
| 2hnd | NVP | Gag-Pol polyprotein | 2.7.7.49 | 0.545 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.544 | |
| 3mec | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.539 | |
| 3m8q | DJZ | Gag-Pol polyprotein | 2.7.7.49 | 0.538 | |
| 3nbp | JGZ | Gag-Pol polyprotein | 2.7.7.49 | 0.535 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.534 | |
| 2opp | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.532 | |
| 1jlc | FTC | Gag-Pol polyprotein | 2.7.7.49 | 0.531 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.531 | |
| 3m8p | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.529 | |
| 1c1c | 612 | Gag-Pol polyprotein | 2.7.7.49 | 0.526 | |
| 1kb9 | SMA | Cytochrome b | / | 0.526 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.526 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.522 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.522 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.522 | |
| 1ezv | SMA | Cytochrome b | / | 0.520 | |
| 1rt1 | MKC | Gag-Pol polyprotein | 2.7.7.49 | 0.520 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.518 | |
| 1s1t | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.511 | |
| 4kfb | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.510 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.509 | |
| 1fko | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.508 | |
| 2opr | HBQ | Gag-Pol polyprotein | 2.7.7.49 | 0.502 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.501 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.499 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.493 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.492 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.491 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.491 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.491 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.491 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.491 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.491 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.490 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.490 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.489 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.489 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.489 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.488 | |
| 4yx6 | FMN | Omega-3 polyunsaturated fatty acid synthase subunit PfaD | / | 0.487 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.486 | |
| 4c2y | MYA | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.485 | |
| 1um0 | FMN | Chorismate synthase | / | 0.484 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.484 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.484 | |
| 4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.484 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.484 | |
| 1nde | MON | Estrogen receptor beta | / | 0.483 | |
| 3dmj | GWE | Pol protein | / | 0.483 | |
| 3p9t | TCL | Repressor | / | 0.483 | |
| 4c2z | MYA | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.483 | |
| 4oav | ACP | 2-5A-dependent ribonuclease | 3.1.26 | 0.483 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.482 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.481 | |
| 1jla | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.480 | |
| 1rt7 | UC4 | Gag-Pol polyprotein | 2.7.7.49 | 0.480 | |
| 2b5j | 3AC | Gag-Pol polyprotein | 2.7.7.49 | 0.480 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.480 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.480 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.480 | |
| 3eej | 53R | Uncharacterized protein | / | 0.479 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.479 | |
| 3m0e | ATP | Transcriptional regulator (NtrC family) | / | 0.479 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.479 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.478 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.478 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.477 | |
| 3bej | MUF | Bile acid receptor | / | 0.477 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.477 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.476 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.476 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.476 | |
| 4ezj | 0SC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.476 | |
| 5e8x | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.476 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.475 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.475 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.475 | |
| 4rw6 | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.475 | |
| 4tv3 | ML9 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.475 | |
| 1klm | SPP | Gag-Pol polyprotein | 2.7.7.49 | 0.474 | |
| 1s1v | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.474 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.474 | |
| 4iv4 | 1GS | Estrogen receptor | / | 0.474 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.474 | |
| 4ucn | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.474 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.473 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.473 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.473 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.472 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.472 | |
| 2cci | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
| 2ibz | SMA | Cytochrome b | / | 0.472 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.472 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.472 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.471 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 2ivu | ZD6 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.471 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.471 | |
| 3r6p | A8S | Abscisic acid receptor PYL10 | / | 0.471 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.471 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.471 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.470 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.470 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.470 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.470 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.470 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.469 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.469 | |
| 1lhv | NOG | Sex hormone-binding globulin | / | 0.469 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.469 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.469 | |
| 3vs0 | VS0 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.469 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.469 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.469 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.469 | |
| 4xdm | GDM | Heat shock cognate 90 kDa protein | / | 0.469 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 1err | RAL | Estrogen receptor | / | 0.468 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.468 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2won | ZZE | Gag-Pol polyprotein | 2.7.7.49 | 0.468 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.468 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.468 | |
| 3mvl | 38P | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.468 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.468 | |
| 4a33 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.468 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.467 | |
| 1uml | FR4 | Adenosine deaminase | 3.5.4.4 | 0.467 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.467 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.467 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.467 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.467 | |
| 1kv2 | B96 | Mitogen-activated protein kinase 14 | / | 0.466 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.466 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.466 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.466 | |
| 3dle | GFA | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
| 4f64 | 0S8 | Fibroblast growth factor receptor 1 | / | 0.466 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.466 | |
| 4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.466 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.466 | |
| 4ogr | ADN | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.466 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 2wug | HPK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.465 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.465 | |
| 3g8e | IS1 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.465 | |
| 4eil | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.465 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.465 | |
| 4mvf | STU | Calcium-dependent protein kinase 2 | 2.7.11.1 | 0.465 | |
| 5amn | DTQ | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.465 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.464 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.464 | |
| 2g5o | DRQ | Estrogen receptor | / | 0.464 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.464 | |
| 2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.464 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.464 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.464 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.464 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.464 | |
| 4as7 | 6LX | Kinesin-like protein KIF11 | / | 0.464 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.464 | |
| 4i5i | 4I5 | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.464 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.463 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.463 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.463 | |
| 1r9o | FLP | Cytochrome P450 2C9 | / | 0.463 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.463 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 3c6u | M22 | Gag-Pol polyprotein | 2.7.7.49 | 0.463 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.463 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.463 | |
| 3r3f | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.463 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.463 | |
| 4dgg | I76 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.463 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.463 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.463 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.463 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.462 | |
| 1kyo | SMA | Cytochrome b | / | 0.462 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.462 | |
| 1sej | F89 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.462 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 2qkr | IXM | Cdc2-like CDK2/CDC28 like protein kinase | / | 0.462 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.462 | |
| 3b8r | 887 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.462 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.462 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.462 | |
| 3qly | 55V | Uncharacterized protein | / | 0.462 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.462 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.462 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.462 | |
| 4ok1 | 198 | Androgen receptor | / | 0.462 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.462 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.462 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.461 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.461 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.461 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.461 | |
| 3cxh | SMA | Cytochrome b | / | 0.461 | |
| 3dok | GWJ | Pol protein | / | 0.461 | |
| 3dol | GWI | Pol protein | / | 0.461 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.461 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.461 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.461 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.461 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.461 | |
| 4m69 | ANP | Receptor-interacting serine/threonine-protein kinase 3 | 2.7.11.1 | 0.461 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.461 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 1e8w | QUE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.460 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.460 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1rdt | 570 | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.460 | |
| 1yin | CM3 | Estrogen receptor | / | 0.460 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.460 | |
| 2duv | 371 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 3l08 | ZIG | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 3nef | PYV | Abscisic acid receptor PYL1 | / | 0.460 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.460 | |
| 3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.460 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.460 | |
| 4h4m | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 5awm | ANP | Stress-activated protein kinase JNK | 2.7.11.24 | 0.460 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 1jkh | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.459 | |
| 1pl8 | NAD | Sorbitol dehydrogenase | 1.1.1.14 | 0.459 | |
| 1sj0 | E4D | Estrogen receptor | / | 0.459 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.459 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 3cy3 | JN5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.459 | |
| 3hv7 | 1AU | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.459 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.459 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.459 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.459 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.459 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.459 | |
| 4okx | 198 | Androgen receptor | / | 0.459 | |
| 4pd6 | URI | Nucleoside permease | / | 0.459 | |
| 5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.459 | |
| 4z34 | ON7 | Lysophosphatidic acid receptor 1 | / | 0.459 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.458 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.458 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.458 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.458 | |
| 2x7f | 824 | TRAF2 and NCK-interacting protein kinase | 2.7.11.1 | 0.458 | |
| 2xx5 | 13N | ATP-dependent molecular chaperone HSP82 | / | 0.458 | |
| 2z4b | DC8 | Estrogen receptor beta | / | 0.458 | |
| 3b9l | AZZ | Serum albumin | / | 0.458 | |
| 3h18 | PMS | Esterase/lipase | / | 0.458 | |
| 3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 4bgq | 38R | Cyclin-dependent kinase-like 5 | 2.7.11.22 | 0.458 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.458 | |
| 4dk5 | 0KO | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.458 | |
| 5i2h | AGI | O-methyltransferase family 2 | / | 0.458 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 1g67 | TZP | Thiamine-phosphate synthase | / | 0.457 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.457 | |
| 1pxx | DIF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.457 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.457 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.457 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.457 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 3k14 | 535 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.457 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.457 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 4anu | EM7 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4b13 | NHW | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.457 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.457 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.457 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.457 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.456 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.456 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.456 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.456 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.456 | |
| 1osf | KOS | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.456 | |
| 1uom | PTI | Estrogen receptor | / | 0.456 | |
| 1wxy | FRK | Adenosine deaminase | 3.5.4.4 | 0.456 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 2btd | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.456 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.456 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.456 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 2yek | EAM | Bromodomain-containing protein 2 | / | 0.456 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 3kkv | B99 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
| 3q2m | CKI | Spectinomycin phosphotransferase | / | 0.456 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.456 | |
| 3zos | 0LI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.456 | |
| 4egn | TWO | Cytochrome P450 | / | 0.456 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.456 | |
| 4lg5 | A1O | Abscisic acid receptor PYL2 | / | 0.456 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 4okt | 198 | Androgen receptor | / | 0.456 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.456 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1lso | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.455 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.455 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.455 | |
| 2bxm | IMN | Serum albumin | / | 0.455 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2j0v | GDP | Rac-like GTP-binding protein ARAC7 | / | 0.455 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2qmz | LDP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.455 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.455 | |
| 3eem | 53V | Uncharacterized protein | / | 0.455 | |
| 3k3j | F4C | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3u4u | LNH | Casein kinase II subunit alpha | 2.7.11.1 | 0.455 | |
| 3vs3 | VSE | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.455 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.455 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.455 | |
| 4q5h | ANP | Protein kinase OspG | 2.7 | 0.455 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.455 | |
| 1d3g | BRE | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.454 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.454 | |
| 2iog | IOG | Estrogen receptor | / | 0.454 | |
| 2ph5 | NAD | Homospermidine synthase | / | 0.454 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.454 | |
| 2uzd | C85 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3eek | 53S | Uncharacterized protein | / | 0.454 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.454 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.454 | |
| 3q9x | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.454 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.454 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4g31 | 0WH | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.454 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.454 | |
| 4j97 | ACP | Fibroblast growth factor receptor 2 | / | 0.454 | |
| 4l8u | 9AZ | Serum albumin | / | 0.454 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.454 | |
| 1osv | CHC | Bile acid receptor | / | 0.453 | |
| 1qiw | DPD | Calmodulin | / | 0.453 | |
| 1uy9 | PU6 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.453 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.453 | |
| 2vdv | SAM | tRNA (guanine-N(7)-)-methyltransferase | / | 0.453 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.453 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.453 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.453 | |
| 3wsb | RWZ | Farnesyltransferase, putative | / | 0.453 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4apu | A2K | Progesterone receptor | / | 0.453 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.453 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.453 | |
| 1brp | RTL | Retinol-binding protein 4 | / | 0.452 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.452 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 1g4s | TPS | Thiamine-phosphate synthase | / | 0.452 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.452 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.452 | |
| 2acw | UPG | Glycosyltransferase | / | 0.452 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.452 | |
| 2d3m | COA | 5,7-dihydroxy-2-methylchromone synthase | 2.3.1.216 | 0.452 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.452 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.452 | |
| 2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.452 | |
| 2rht | C1E | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.452 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.452 | |
| 2ybo | SAH | Methyltransferase | / | 0.452 | |
| 2yej | XQK | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.452 | |
| 3cse | N22 | Uncharacterized protein | / | 0.452 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.452 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.452 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.452 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4dit | 0KD | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.452 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.452 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.452 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.452 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 4ix5 | ANP | Uncharacterized protein | / | 0.452 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.452 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.451 | |
| 1cx2 | S58 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.451 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.451 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1onp | FOM | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.451 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.451 | |
| 1t1r | IMB | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.451 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.451 | |
| 1xqc | AEJ | Estrogen receptor | / | 0.451 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 2a5u | QYT | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.451 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.451 | |
| 2c6e | HPM | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 2vwy | 7X5 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.451 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.451 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.451 | |
| 3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.451 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.451 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.451 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.451 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.451 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1aqb | RTL | Retinol-binding protein 4 | / | 0.450 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.450 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.450 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 2o3z | AI7 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.450 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.450 | |
| 2pzp | ACP | Fibroblast growth factor receptor 2 | / | 0.450 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 2w9s | TOP | Dihydrofolate reductase type 1 from Tn4003 | 1.5.1.3 | 0.450 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 2ykc | YKC | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.450 | |
| 3r37 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.450 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.450 | |
| 4bcn | T9N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 4gue | QCT | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.450 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.450 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.450 | |
| 4ku2 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.450 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.450 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.450 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.449 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.449 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2ay8 | 4TB | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.449 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.449 | |
| 2fwy | H64 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2ynf | WHU | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.449 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.449 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.449 | |
| 3iqe | F42 | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.449 | |
| 3ruq | ADP | Chaperonin | / | 0.449 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3u8d | U8D | Phospholipase A2, membrane associated | / | 0.449 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 3uxh | UXH | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.449 | |
| 3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.449 | |
| 3zra | ORB | Progesterone receptor | / | 0.449 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4lvg | 20O | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.449 | |
| 4oau | ADP | 2-5A-dependent ribonuclease | 3.1.26 | 0.449 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.449 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.449 | |
| 1chw | HXC | Chalcone synthase 2 | 2.3.1.74 | 0.448 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.448 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.448 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.448 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.448 | |
| 2ior | ADP | Chaperone protein HtpG | / | 0.448 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.448 | |
| 2puh | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.448 | |
| 2xiz | XIZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.448 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.448 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.448 | |
| 3jpv | 1DR | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.448 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 3mfr | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.448 | |
| 3q9z | TXQ | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.448 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4ez5 | 0RS | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.448 | |
| 4ndn | SAM | S-adenosylmethionine synthase isoform type-2 | 2.5.1.6 | 0.448 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.448 | |
| 5l7d | CLR | Smoothened homolog | / | 0.448 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1o6y | ACP | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.447 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.447 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2j0k | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.447 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.447 | |
| 2l98 | STL | Troponin C, slow skeletal and cardiac muscles | / | 0.447 | |
| 2o0u | C0M | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.447 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2pir | DHT | Androgen receptor | / | 0.447 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.447 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.447 | |
| 3gxo | MQA | Mitomycin biosynthesis 6-O-methyltransferase | / | 0.447 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3juh | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.447 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.447 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3ox1 | 695 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 3pej | BC2 | Endoplasmin homolog, putative | / | 0.447 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.447 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.447 | |
| 3v1n | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.447 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.447 | |
| 4a9h | TVP | Bromodomain-containing protein 2 | / | 0.447 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.447 | |
| 4f7l | 0SO | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.447 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 4i41 | MIX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.447 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 4mbl | 26L | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 4p6x | HCY | Glucocorticoid receptor | / | 0.447 | |
| 4wbo | ANW | Rhodopsin kinase | / | 0.447 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.447 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.447 | |
| 5a3b | APR | SIR2 family protein | / | 0.447 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1ezf | IN0 | Squalene synthase | 2.5.1.21 | 0.446 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.446 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.446 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 2gu8 | 796 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 2nu9 | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.446 | |
| 2p15 | EZT | Estrogen receptor | / | 0.446 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 3amy | AGI | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.446 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.446 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3o0i | P54 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3r32 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.446 | |
| 3r9d | X6B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3t1a | 5MA | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.446 | |
| 3vs6 | VSH | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.446 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.446 | |
| 3w2o | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4bb4 | 32W | Ephrin type-B receptor 4 | 2.7.10.1 | 0.446 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4jvn | YUG | Estrogen sulfotransferase | 2.8.2.4 | 0.446 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.446 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.446 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.446 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 5ikq | JMS | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.446 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.446 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.445 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2bil | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.445 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.445 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.445 | |
| 2qtg | MTH | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 1 | 3.2.2.9 | 0.445 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.445 | |
| 2vag | V25 | Dual specificity protein kinase CLK1 | 2.7.12.1 | 0.445 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.445 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2zce | PYL | Pyrrolysine--tRNA ligase | / | 0.445 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.445 | |
| 3aid | ARQ | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3bv3 | P39 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3cx5 | SMA | Cytochrome b | / | 0.445 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.445 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.445 | |
| 3zux | TCH | Transporter | / | 0.445 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.445 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.445 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.445 | |
| 1bq6 | COA | Chalcone synthase 2 | 2.3.1.74 | 0.444 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.444 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.444 | |
| 1sbr | VIB | Putative HMP/thiamine-binding protein YkoF | / | 0.444 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.444 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.444 | |
| 1zky | 689 | Estrogen receptor | / | 0.444 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 2bx8 | AZQ | Serum albumin | / | 0.444 | |
| 2c0t | L3G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.444 | |
| 2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.444 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.444 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.444 | |
| 2wue | KEK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.444 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.444 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.444 | |
| 3e93 | 19B | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.444 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.444 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.444 | |
| 3kdi | A8S | Abscisic acid receptor PYL2 | / | 0.444 | |
| 3o8t | BMU | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3oyz | ACO | Malate synthase | 2.3.3.9 | 0.444 | |
| 3qdd | 94M | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.444 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 4aot | GW8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.444 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.444 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.444 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.444 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.444 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.444 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1tqp | ATP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.443 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.443 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.443 | |
| 2i51 | FMN | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding | / | 0.443 | |
| 2pog | WST | Estrogen receptor | / | 0.443 | |
| 2ydw | WSH | Bromodomain-containing protein 2 | / | 0.443 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.443 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.443 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.443 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.443 | |
| 3rps | 4B0 | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 3upj | U03 | Gag-Pol polyprotein | / | 0.443 | |
| 3vqu | O22 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.443 | |
| 3vs4 | VSF | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.443 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4inb | 1F6 | Gag protein | / | 0.443 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.443 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.443 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.443 | |
| 4ug7 | 1EV | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.443 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.442 | |
| 1l2i | ETC | Estrogen receptor | / | 0.442 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2f2c | AP9 | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.442 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.442 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.442 | |
| 2jfa | RAL | Estrogen receptor | / | 0.442 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.442 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.442 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.442 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.442 | |
| 2xir | 00J | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 2yem | WSH | Bromodomain-containing protein 4 | / | 0.442 | |
| 2yjx | YJX | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.442 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.442 | |
| 3c3e | FO1 | 2-phospho-L-lactate transferase | / | 0.442 | |
| 3l70 | JZV | Cytochrome b | / | 0.442 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.442 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.442 | |
| 3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.442 | |
| 3zvv | XAZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.442 | |
| 4a9e | 3PF | Bromodomain-containing protein 2 | / | 0.442 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4gqi | M49 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.442 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.442 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.442 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 4jrv | KJV | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 4xld | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.442 | |
| 1axw | MTX | Thymidylate synthase | / | 0.441 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.441 | |
| 1pp9 | SMA | Cytochrome b | / | 0.441 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 1zz2 | B11 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2hk5 | 1BM | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.441 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.441 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.441 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.441 | |
| 2yiu | SMA | Cytochrome b | / | 0.441 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.441 | |
| 3fi3 | JK2 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.441 | |
| 3h1j | SMA | Cytochrome b | / | 0.441 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.441 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3ml9 | ML9 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.441 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.441 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4dgm | AGI | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.441 | |
| 4l9q | 9TP | Serum albumin | / | 0.441 | |
| 4mxo | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.441 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.441 | |
| 4ug7 | H4B | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.441 | |
| 1hk2 | T44 | Serum albumin | / | 0.440 | |
| 1ie4 | T44 | Transthyretin | / | 0.440 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1sqv | UHD | Cytochrome b | / | 0.440 | |
| 1tlc | F89 | Thymidylate synthase | / | 0.440 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.440 | |
| 2c96 | ATP | Psp operon transcriptional activator | / | 0.440 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.440 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2v1a | FMN | NPH1-1 | / | 0.440 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.440 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.440 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.440 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.440 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.440 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.440 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.440 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.440 | |
| 3wiy | LC6 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.440 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 4b1f | KRH | Glutamate racemase | / | 0.440 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.440 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.440 | |
| 4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.440 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.440 | |
| 4jr3 | KJR | Epidermal growth factor receptor | 2.7.10.1 | 0.440 | |
| 4olm | 198 | Androgen receptor | / | 0.440 | |
| 4zvm | DM2 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 |