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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1s1wUC1Gag-Pol polyprotein2.7.7.49

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1s1wUC1Gag-Pol polyprotein2.7.7.491.000
1tl1H18Gag-Pol polyprotein2.7.7.490.773
2opqHBQGag-Pol polyprotein2.7.7.490.708
1tktH12Gag-Pol polyprotein2.7.7.490.707
1revTB9Gag-Pol polyprotein2.7.7.490.695
1tkzH16Gag-Pol polyprotein2.7.7.490.685
1tl3H20Gag-Pol polyprotein2.7.7.490.656
1ikwEFZGag-Pol polyprotein2.7.7.490.654
1rt4UC1Gag-Pol polyprotein2.7.7.490.645
3i0rRT3Gag-Pol polyprotein2.7.7.490.638
1hnvTBOGag-Pol polyprotein2.7.7.490.631
2vg5NNCGag-Pol polyprotein2.7.7.490.630
1vruAAPGag-Pol polyprotein2.7.7.490.628
2vg7NNIGag-Pol polyprotein2.7.7.490.622
3meeT27Gag-Pol polyprotein2.7.7.490.621
1ikxPNUGag-Pol polyprotein2.7.7.490.615
1hpzAAPGag-Pol polyprotein2.7.7.490.613
1rt5UC2Gag-Pol polyprotein2.7.7.490.612
2rf2MRXGag-Pol polyprotein2.7.7.490.610
2zd1T27Gag-Pol polyprotein2.7.7.490.607
3megT27Gag-Pol polyprotein2.7.7.490.605
4ko0JLJGag-Pol polyprotein2.7.7.490.605
1c1bGCAGag-Pol polyprotein2.7.7.490.599
1ep4S11Gag-Pol polyprotein2.7.7.490.595
1hniAAAGag-Pol polyprotein2.7.7.490.593
3i0sRT7Gag-Pol polyprotein2.7.7.490.592
1rt2TNKGag-Pol polyprotein2.7.7.490.591
4i2pG73Gag-Pol polyprotein2.7.7.490.591
2ban357Gag-Pol polyprotein2.7.7.490.588
1s6qTPBGag-Pol polyprotein2.7.7.490.586
1ikvEFZGag-Pol polyprotein2.7.7.490.585
1eetBFUGag-Pol polyprotein2.7.7.490.584
4id5T27Gag-Pol polyprotein2.7.7.490.584
1tkxGWBGag-Pol polyprotein2.7.7.490.580
4ig3T27Gag-Pol polyprotein2.7.7.490.580
1s9eADBGag-Pol polyprotein2.7.7.490.576
4kko1REGag-Pol polyprotein2.7.7.490.576
4g1qT27Gag-Pol polyprotein2.7.7.490.575
3qlhT27Gag-Pol polyprotein2.7.7.490.574
4i7fNVEGag-Pol polyprotein2.7.7.490.572
4ifvT27Gag-Pol polyprotein2.7.7.490.569
1jlqSBNGag-Pol polyprotein2.7.7.490.567
2opsHBQGag-Pol polyprotein2.7.7.490.564
1fk9EFZGag-Pol polyprotein2.7.7.490.562
3ffi3OBGag-Pol polyprotein2.7.7.490.562
3is9AC7Gag-Pol polyprotein2.7.7.490.562
2ze2T27Gag-Pol polyprotein2.7.7.490.561
3lanKBTGag-Pol polyprotein2.7.7.490.561
3med65BGag-Pol polyprotein2.7.7.490.556
1ikyMSDGag-Pol polyprotein2.7.7.490.555
1jlgUC1Gag-Pol polyprotein2.7.7.490.554
5cyqT27Gag-Pol polyprotein2.7.7.490.552
2hndNVPGag-Pol polyprotein2.7.7.490.545
3lamKRPGag-Pol polyprotein2.7.7.490.544
3mec65BGag-Pol polyprotein2.7.7.490.539
3m8qDJZGag-Pol polyprotein2.7.7.490.538
3nbpJGZGag-Pol polyprotein2.7.7.490.535
1hquHBYGag-Pol polyprotein2.7.7.490.534
2oppHBQGag-Pol polyprotein2.7.7.490.532
1jlcFTCGag-Pol polyprotein2.7.7.490.531
2hnzPC0Gag-Pol polyprotein2.7.7.490.531
3m8p65BGag-Pol polyprotein2.7.7.490.529
1c1c612Gag-Pol polyprotein2.7.7.490.526
1kb9SMACytochrome b/0.526
4i2q1BTGag-Pol polyprotein2.7.7.490.526
3irxUDRGag-Pol polyprotein2.7.7.490.522
3lalKRVGag-Pol polyprotein2.7.7.490.522
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.522
1ezvSMACytochrome b/0.520
1rt1MKCGag-Pol polyprotein2.7.7.490.520
1tvrTB9Gag-Pol polyprotein2.7.7.490.518
1s1tUC1Gag-Pol polyprotein2.7.7.490.511
4kfbT27Gag-Pol polyprotein2.7.7.490.510
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.509
1fkoEFZGag-Pol polyprotein2.7.7.490.508
2oprHBQGag-Pol polyprotein2.7.7.490.502
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.501
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.499
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.493
1qxlFR8Adenosine deaminase3.5.4.40.492
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.491
1kzjCB3Thymidylate synthase/0.491
1v7aFRCAdenosine deaminase3.5.4.40.491
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.491
3bgrT27Gag-Pol polyprotein2.7.7.490.491
3gc9B45Mitogen-activated protein kinase 112.7.11.240.491
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.490
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.490
1o5rFR9Adenosine deaminase3.5.4.40.489
4em9TCEPeroxisome proliferator-activated receptor gamma/0.489
5k2dZMAAdenosine receptor A2a/0.489
1m7aMQUDihydrofolate reductase1.5.1.30.488
3nr4PYVAbscisic acid receptor PYL2/0.488
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.487
2c27ACOMycothiol acetyltransferase2.3.1.1890.486
4c2yMYAGlycylpeptide N-tetradecanoyltransferase 1/0.485
1um0FMNChorismate synthase/0.484
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.484
3hz5Z64Heat shock protein HSP 90-alpha/0.484
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.484
4ocvANPAminoglycoside phosphotransferase/0.484
1ndeMONEstrogen receptor beta/0.483
3dmjGWEPol protein/0.483
3p9tTCLRepressor/0.483
4c2zMYAGlycylpeptide N-tetradecanoyltransferase 1/0.483
4oavACP2-5A-dependent ribonuclease3.1.260.483
1t88CAMCamphor 5-monooxygenase1.14.15.10.482
3nj0PYVAbscisic acid receptor PYL2/0.481
1jlaTNKGag-Pol polyprotein2.7.7.490.480
1rt7UC4Gag-Pol polyprotein2.7.7.490.480
2b5j3ACGag-Pol polyprotein2.7.7.490.480
4gmy0X5Tyrosine-protein kinase JAK2/0.480
4jdaA9SAbscisic acid receptor PYL3/0.480
4wa9AXITyrosine-protein kinase ABL12.7.10.20.480
3eej53RUncharacterized protein/0.479
3lakKR1Gag-Pol polyprotein2.7.7.490.479
3m0eATPTranscriptional regulator (NtrC family)/0.479
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.479
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.478
4g1y0VOVitamin D3 receptor A/0.478
1p0hACOMycothiol acetyltransferase2.3.1.1890.477
3bejMUFBile acid receptor/0.477
3qlxQLRUncharacterized protein/0.477
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.476
2hb8MVDVitamin D3 receptor/0.476
2wufKEM4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.476
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
5e8xSTUTGF-beta receptor type-12.7.11.300.476
1zhzERGOxysterol-binding protein homolog 4/0.475
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.475
3t3q9PLCytochrome P450 2A61.14.130.475
4rw6494Gag-Pol polyprotein2.7.7.490.475
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.475
1klmSPPGag-Pol polyprotein2.7.7.490.474
1s1vTNKGag-Pol polyprotein2.7.7.490.474
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.474
4iv41GSEstrogen receptor/0.474
4ly91YYGlucokinase regulatory protein/0.474
4ucnMYAGlycylpeptide N-tetradecanoyltransferase/0.474
1d2sDHTSex hormone-binding globulin/0.473
1l2jETCEstrogen receptor beta/0.473
1w06W05Isopenicillin N synthase1.21.3.10.473
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
1ia1TQ3Dihydrofolate reductase1.5.1.30.472
1nq7ARLNuclear receptor ROR-beta/0.472
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.472
2cciATPCyclin-dependent kinase 22.7.11.220.472
2ibzSMACytochrome b/0.472
3gphOIDCytochrome P450 2E11.14.130.472
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.472
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
1fm4DXCMajor pollen allergen Bet v 1-L/0.471
1ia2TQ4Dihydrofolate reductase1.5.1.30.471
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.471
3lfcZ86Mitogen-activated protein kinase 14/0.471
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.471
3r6pA8SAbscisic acid receptor PYL10/0.471
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
4iarERM5-hydroxytryptamine receptor 1B/0.471
1ml6GBXGlutathione S-transferase A22.5.1.180.470
2pmdGNPTranslation initiation factor 2 subunit gamma/0.470
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
2z7gEH9Adenosine deaminase3.5.4.40.470
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.470
4kfj1R0Dihydrofolate reductase1.5.1.30.470
1bozPRDDihydrofolate reductase1.5.1.30.469
1jpaANPEphrin type-B receptor 22.7.10.10.469
1ju6LYAThymidylate synthase2.1.1.450.469
1lhvNOGSex hormone-binding globulin/0.469
2jn3JN3Fatty acid-binding protein, liver/0.469
2y30SM8Putative repressor SimReg2/0.469
3vs0VS0Tyrosine-protein kinase HCK2.7.10.20.469
3vspEK8Peroxisome proliferator-activated receptor gamma/0.469
4dscA8SAbscisic acid receptor PYL3/0.469
4i8vBHFCytochrome P450 1A11.14.14.10.469
4ia7BIVVitamin D3 receptor A/0.469
4xdmGDMHeat shock cognate 90 kDa protein/0.469
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.469
1errRALEstrogen receptor/0.468
1ie9VDXVitamin D3 receptor/0.468
1vj3TABDihydrofolate reductase1.5.1.30.468
2wonZZEGag-Pol polyprotein2.7.7.490.468
3c3dFO12-phospho-L-lactate transferase/0.468
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.468
3mvl38PMitogen-activated protein kinase 14/0.468
3negPYVAbscisic acid receptor PYL1/0.468
3vt5YI2Vitamin D3 receptor/0.468
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.468
1ly3COGDihydrofolate reductase1.5.1.30.467
1n4hREANuclear receptor ROR-beta/0.467
1umlFR4Adenosine deaminase3.5.4.40.467
2vzmNRBCytochrome P450 monooxygenase PikC/0.467
2ykeYKEHeat shock protein HSP 90-alpha/0.467
3d0bSNXHeat shock protein HSP 90-alpha/0.467
3dxjNE6DNA-directed RNA polymerase subunit beta/0.467
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.467
3s7a684Dihydrofolate reductase1.5.1.30.467
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
4iui1GQEstrogen receptor/0.467
1kv2B96Mitogen-activated protein kinase 14/0.466
1ot7CHCBile acid receptor/0.466
1v79FR7Adenosine deaminase3.5.4.40.466
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.466
3dleGFAGag-Pol polyprotein2.7.7.490.466
4f640S8Fibroblast growth factor receptor 1/0.466
4i22IREEpidermal growth factor receptor2.7.10.10.466
4lmuQUESerine/threonine-protein kinase pim-12.7.11.10.466
4nb6444Nuclear receptor ROR-gamma/0.466
4ogrADNCyclin-dependent kinase 92.7.11.220.466
1dr3TAPDihydrofolate reductase1.5.1.30.465
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
2wugHPK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.465
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.465
3g8eIS1Nicotinamide phosphoribosyltransferase2.4.2.120.465
4eilCB3Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.465
4g1z0VPVitamin D3 receptor A/0.465
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.465
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.465
1rdtL79Retinoic acid receptor RXR-alpha/0.464
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.464
2g5oDRQEstrogen receptor/0.464
2hcdBIVVitamin D3 receptor A/0.464
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.464
3cgeCOACoenzyme A disulfide reductase/0.464
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.464
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.464
4as76LXKinesin-like protein KIF11/0.464
4enhFVXCholesterol 24-hydroxylase/0.464
4i5i4I5NAD-dependent protein deacetylase sirtuin-13.5.10.464
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
1kt3RTLRetinol-binding protein 4/0.463
1pq6965Oxysterols receptor LXR-beta/0.463
1r9oFLPCytochrome P450 2C9/0.463
2j5xGSPADP-ribosylation factor 6/0.463
3axwTIDCasein kinase II subunit alpha2.7.11.10.463
3c6uM22Gag-Pol polyprotein2.7.7.490.463
3ctj320Hepatocyte growth factor receptor2.7.10.10.463
3mdvCL6Cholesterol 24-hydroxylase/0.463
3r3f4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.463
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.463
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.463
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
4grb0XGCasein kinase II subunit alpha2.7.11.10.463
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4o71CPBBromodomain-containing protein 4/0.463
4y8wSTRSteroid 21-hydroxylase/0.463
1cbrREACellular retinoic acid-binding protein 1/0.462
1kyoSMACytochrome b/0.462
1rkhVD2Vitamin D3 receptor/0.462
1sejF89Bifunctional dihydrofolate reductase-thymidylate synthase/0.462
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.462
2qblCAMCamphor 5-monooxygenase1.14.15.10.462
2qkrIXMCdc2-like CDK2/CDC28 like protein kinase/0.462
2vn0TDZCytochrome P450 2C8/0.462
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.462
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.462
3dhoB2MStreptogramin A acetyltransferase2.3.10.462
3qly55VUncharacterized protein/0.462
3wowANPCasein kinase II subunit alpha2.7.11.10.462
4ejgNCTCytochrome P450 2A131.14.14.10.462
4gk2L66Ephrin type-A receptor 32.7.10.10.462
4ok1198Androgen receptor/0.462
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.462
5e8wSTUTGF-beta receptor type-12.7.11.300.462
1hb3SCVIsopenicillin N synthase1.21.3.10.461
1s0zEB1Vitamin D3 receptor/0.461
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.461
2fszOHTEstrogen receptor beta/0.461
2iviACWIsopenicillin N synthase1.21.3.10.461
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.461
2zb45OPProstaglandin reductase 21.3.1.480.461
3cxhSMACytochrome b/0.461
3dokGWJPol protein/0.461
3dolGWIPol protein/0.461
3h0a9RARetinoic acid receptor RXR-alpha/0.461
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.461
4ap1NAPSteroid monooxygenase/0.461
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4h9814QUncharacterized protein/0.461
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.461
4nh82LCHeat shock protein HSP 90-alpha/0.461
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.461
5k2cZMAAdenosine receptor A2a/0.461
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
1fmjRTLRetinol dehydratase/0.460
1ia4TQ6Dihydrofolate reductase1.5.1.30.460
1lb9DNQGlutamate receptor 2/0.460
1oc1ASVIsopenicillin N synthase1.21.3.10.460
1rdt570Peroxisome proliferator-activated receptor gamma/0.460
1tduDURThymidylate synthase/0.460
1yinCM3Estrogen receptor/0.460
1zhwHC2Oxysterol-binding protein homolog 4/0.460
2duv371Cyclin-dependent kinase 22.7.11.220.460
3bgzVX3Serine/threonine-protein kinase pim-12.7.11.10.460
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
3nefPYVAbscisic acid receptor PYL1/0.460
3qlzQLZUncharacterized protein/0.460
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.460
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.460
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.460
4h4m494Gag-Pol polyprotein2.7.7.490.460
5awmANPStress-activated protein kinase JNK2.7.11.240.460
5cccDDFDihydrofolate reductase1.5.1.30.460
1aoeGW3Dihydrofolate reductase1.5.1.30.459
1jkhEFZGag-Pol polyprotein2.7.7.490.459
1kt6RTLRetinol-binding protein 4/0.459
1pl8NADSorbitol dehydrogenase1.1.1.140.459
1sj0E4DEstrogen receptor/0.459
2hasC3OVitamin D3 receptor/0.459
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.459
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.459
3hv71AUMitogen-activated protein kinase 14/0.459
3icsADPCoenzyme A disulfide reductase/0.459
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.459
3q5kD1UHeat shock protein 83-1/0.459
3vg9ZMAAdenosine receptor A2a/0.459
4c9pCAMCytochrome P450/0.459
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.459
4okx198Androgen receptor/0.459
4pd6URINucleoside permease/0.459
5cvfATPCasein kinase II subunit alpha2.7.11.10.459
4z34ON7Lysophosphatidic acid receptor 1/0.459
1nceCB3Thymidylate synthase/0.458
1txiTX5Vitamin D3 receptor/0.458
2h96893Mitogen-activated protein kinase 82.7.11.240.458
2pmoHMDProtein kinase 7/0.458
2x7f824TRAF2 and NCK-interacting protein kinase2.7.11.10.458
2xx513NATP-dependent molecular chaperone HSP82/0.458
2z4bDC8Estrogen receptor beta/0.458
3b9lAZZSerum albumin/0.458
3h18PMSEsterase/lipase/0.458
3i8aN22Dihydrofolate reductase1.5.1.30.458
4bgq38RCyclin-dependent kinase-like 52.7.11.220.458
4dbzNDPPutative ketoacyl reductase1.3.10.458
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.458
5i2hAGIO-methyltransferase family 2/0.458
1enzNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
1g67TZPThiamine-phosphate synthase/0.457
1lhwESMSex hormone-binding globulin/0.457
1pxxDIFProstaglandin G/H synthase 21.14.99.10.457
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
2hamC33Vitamin D3 receptor/0.457
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.457
2z3uCRRCytochrome P450/0.457
3frdDHFDihydrofolate reductase1.5.1.30.457
3fywXCFDihydrofolate reductase1.5.1.30.457
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.457
3k145352-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.457
3kpzZNEVitamin D3 receptor/0.457
4a83DXCMajor pollen allergen Bet v 1-A/0.457
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4b13NHWGlycylpeptide N-tetradecanoyltransferase/0.457
4bchT7ZCyclin-dependent kinase 92.7.11.220.457
4cf7ADPAdenylate kinase/0.457
4ejh0QACytochrome P450 2A131.14.14.10.457
5uviZMAAdenosine receptor A2a/0.457
1db1VDXVitamin D3 receptor/0.456
1ek2CDUBifunctional epoxide hydrolase 2/0.456
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.456
1hvyD16Thymidylate synthase2.1.1.450.456
1jujLYAThymidylate synthase2.1.1.450.456
1osfKOSHeat shock protein HSP 90-alpha/0.456
1s19MC9Vitamin D3 receptor/0.456
1uomPTIEstrogen receptor/0.456
1wxyFRKAdenosine deaminase3.5.4.40.456
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
2btdADPPEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.456
2vrbNAPTriphenylmethane reductase/0.456
2w3vTOPDihydrofolate reductase/0.456
2yee2ECHeat shock protein HSP 90-alpha/0.456
2yekEAMBromodomain-containing protein 2/0.456
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.456
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.456
3q2mCKISpectinomycin phosphotransferase/0.456
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.456
3zos0LIEpithelial discoidin domain-containing receptor 12.7.10.10.456
4egnTWOCytochrome P450/0.456
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4g1d0VKVitamin D3 receptor A/0.456
4lg5A1OAbscisic acid receptor PYL2/0.456
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.456
4okt198Androgen receptor/0.456
4r20AERCytochrome P450 family 17 polypeptide 2/0.456
1bk0ACVIsopenicillin N synthase1.21.3.10.455
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.455
1lwlDSOCamphor 5-monooxygenase1.14.15.10.455
1og5SWFCytochrome P450 2C9/0.455
1uuoBRFDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.455
2bxmIMNSerum albumin/0.455
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
2j0vGDPRac-like GTP-binding protein ARAC7/0.455
2q59240Peroxisome proliferator-activated receptor gamma/0.455
2qmzLDPRibosyldihydronicotinamide dehydrogenase [quinone]/0.455
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.455
3eem53VUncharacterized protein/0.455
3k3jF4CMitogen-activated protein kinase 14/0.455
3u4uLNHCasein kinase II subunit alpha2.7.11.10.455
3vs3VSETyrosine-protein kinase HCK2.7.10.20.455
4bcqTJFCyclin-dependent kinase 22.7.11.220.455
4fhi0S4Vitamin D3 receptor A/0.455
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4ia1BIVVitamin D3 receptor A/0.455
4q5hANPProtein kinase OspG2.70.455
4rupH97Vitamin D3 receptor A/0.455
1d3gBREDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.454
1klkPMDDihydrofolate reductase1.5.1.30.454
2fzhDH1Dihydrofolate reductase1.5.1.30.454
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.454
2iogIOGEstrogen receptor/0.454
2ph5NADHomospermidine synthase/0.454
2qe4JJ3Estrogen receptor/0.454
2uzdC85Cyclin-dependent kinase 22.7.11.220.454
2z97CAMCamphor 5-monooxygenase1.14.15.10.454
3d84NDPDihydrofolate reductase1.5.1.30.454
3eek53SUncharacterized protein/0.454
3koo24DBifunctional epoxide hydrolase 23.3.2.100.454
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
3q9xEMOCasein kinase II subunit alpha2.7.11.10.454
3td8D2RDihydrofolate reductase1.5.1.30.454
3uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.454
3w0yDS4Vitamin D3 receptor/0.454
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.454
3zoiM2WIsopenicillin N synthase1.21.3.10.454
4g310WHEukaryotic translation initiation factor 2-alpha kinase 32.7.11.10.454
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.454
4iw8KN3Estrogen receptor/0.454
4j97ACPFibroblast growth factor receptor 2/0.454
4l8u9AZSerum albumin/0.454
5k2bZMAAdenosine receptor A2a/0.454
3reyXACAdenosine receptor A2a/0.454
1osvCHCBile acid receptor/0.453
1qiwDPDCalmodulin/0.453
1uy9PU6Heat shock protein HSP 90-alpha/0.453
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.453
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.453
2vdvSAMtRNA (guanine-N(7)-)-methyltransferase/0.453
2zjwREFCasein kinase II subunit alpha2.7.11.10.453
3kf7L9GMitogen-activated protein kinase 14/0.453
3qm4PN0Cytochrome P450 2D6/0.453
3rak03ZCyclin-dependent kinase 22.7.11.220.453
3ua506XCytochrome P450 2B61.14.130.453
3wsbRWZFarnesyltransferase, putative/0.453
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4apuA2KProgesterone receptor/0.453
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4g210VPVitamin D3 receptor A/0.453
4h9506UDihydrofolate reductase1.5.1.30.453
4kak06UDihydrofolate reductase1.5.1.30.453
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
4uyf73BBromodomain-containing protein 2/0.453
1brpRTLRetinol-binding protein 4/0.452
1dkfBMSRetinoic acid receptor alpha/0.452
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
1g4sTPSThiamine-phosphate synthase/0.452
1h1r6CPCyclin-dependent kinase 22.7.11.220.452
1hb1OCVIsopenicillin N synthase1.21.3.10.452
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
1vjy460TGF-beta receptor type-12.7.11.300.452
2acwUPGGlycosyltransferase/0.452
2bbqPFGThymidylate synthase/0.452
2d3mCOA5,7-dihydroxy-2-methylchromone synthase2.3.1.2160.452
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.452
2fziDH3Dihydrofolate reductase1.5.1.30.452
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.452
2o4rVD5Vitamin D3 receptor/0.452
2py3ACPFibroblast growth factor receptor 2/0.452
2rhtC1E2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.452
2vwz7X6Ephrin type-B receptor 42.7.10.10.452
2yboSAHMethyltransferase/0.452
2yejXQKHeat shock protein HSP 90-alpha/0.452
3a1l2CCCytochrome P450/0.452
3cseN22Uncharacterized protein/0.452
3njoPYVAbscisic acid receptor PYR1/0.452
3qlrQLRDihydrofolate reductase1.5.1.30.452
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.452
4alhA9PBromodomain-containing protein 2/0.452
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.452
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.452
4eiyZMAAdenosine receptor A2a/0.452
4fhh0U3Vitamin D3 receptor A/0.452
4ia2BIVVitamin D3 receptor A/0.452
4ix5ANPUncharacterized protein/0.452
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.452
1cqp803Integrin alpha-L/0.451
1cx2S58Prostaglandin G/H synthase 21.14.99.10.451
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
1ndzFR5Adenosine deaminase3.5.4.40.451
1nooCAHCamphor 5-monooxygenase1.14.15.10.451
1onpFOM1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.451
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
1phePIYCamphor 5-monooxygenase1.14.15.10.451
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.451
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.451
1xddAAYIntegrin alpha-L/0.451
1xqcAEJEstrogen receptor/0.451
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
2azyCHDPhospholipase A2, major isoenzyme3.1.1.40.451
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.451
2c6eHPMAurora kinase A2.7.11.10.451
2drcMTXDihydrofolate reductase1.5.1.30.451
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.451
2vwy7X5Ephrin type-B receptor 42.7.10.10.451
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.451
3a60STURibosomal protein S6 kinase beta-12.7.11.10.451
3m08RARDihydrofolate reductase1.5.1.30.451
3oiaA31Camphor 5-monooxygenase1.14.15.10.451
3oom507Activin receptor type-12.7.11.300.451
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.451
3vt8YI3Vitamin D3 receptor/0.451
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4ib4ERM5-hydroxytryptamine receptor 2B/0.451
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.451
5jtbZMAAdenosine receptor A2a/0.451
1aqbRTLRetinol-binding protein 4/0.450
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.450
2hw2RFPRifampin ADP-ribosyl transferase/0.450
2iw84SPCyclin-dependent kinase 22.7.11.220.450
2o3zAI7UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.450
2oaxSNLMineralocorticoid receptor/0.450
2pzpACPFibroblast growth factor receptor 2/0.450
2qboCAMCamphor 5-monooxygenase1.14.15.10.450
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.450
2yejZZ3Heat shock protein HSP 90-alpha/0.450
2ykcYKCHeat shock protein HSP 90-alpha/0.450
3ix9MTXDihydrofolate reductase1.5.1.30.450
3oezSTIProto-oncogene tyrosine-protein kinase Src2.7.10.20.450
3r374CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.450
3r3b4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.450
4bcnT9NCyclin-dependent kinase 22.7.11.220.450
4dc0NDPPutative ketoacyl reductase1.3.10.450
4gueQCTRibosomal protein S6 kinase alpha-32.7.11.10.450
4jlm1NNDeoxycytidine kinase2.7.1.740.450
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.450
4ku2MYA3-oxoacyl-[ACP] synthase III/0.450
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.450
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.450
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.450
1bygSTUTyrosine-protein kinase CSK/0.449
1disBDMDihydrofolate reductase1.5.1.30.449
1dz6CAMCamphor 5-monooxygenase1.14.15.10.449
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
1upw444Oxysterols receptor LXR-beta/0.449
1uy7PU4Heat shock protein HSP 90-alpha/0.449
1uy8PU5Heat shock protein HSP 90-alpha/0.449
2ay84TBAromatic-amino-acid aminotransferase2.6.1.570.449
2c3qGTXGlutathione S-transferase theta-12.5.1.180.449
2fwyH64Heat shock protein HSP 90-alpha/0.449
2uzbC75Cyclin-dependent kinase 22.7.11.220.449
2ykjYKJHeat shock protein HSP 90-alpha/0.449
2ynfWHUGag-Pol polyprotein2.7.7.490.449
3bfa9ODOdorant binding protein ASP1/0.449
3da24MDCarbonic anhydrase 134.2.1.10.449
3h4vDVPPteridine reductase 11.5.1.330.449
3iqeF42F420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.449
3ruqADPChaperonin/0.449
3sruQ26Dihydrofolate reductase1.5.1.30.449
3u8dU8DPhospholipase A2, membrane associated/0.449
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.449
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.449
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.449
3zraORBProgesterone receptor/0.449
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4ixgIXGDihydrofolate reductase1.5.1.30.449
4lvg20ONicotinamide phosphoribosyltransferase2.4.2.120.449
4oauADP2-5A-dependent ribonuclease3.1.260.449
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.449
3emlZMAAdenosine receptor A2a/0.449
1chwHXCChalcone synthase 22.3.1.740.448
1jtqLY3Thymidylate synthase/0.448
1s9qOHTEstrogen-related receptor gamma/0.448
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
2h94FADLysine-specific histone demethylase 1A10.448
2hb7O1CVitamin D3 receptor/0.448
2iorADPChaperone protein HtpG/0.448
2jedLG8Protein kinase C theta type2.7.11.130.448
2puhHPK2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.448
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.448
2ydoADNAdenosine receptor A2a/0.448
3ar7TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.448
3cd2MTXDihydrofolate reductase1.5.1.30.448
3cgdCOACoenzyme A disulfide reductase/0.448
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.448
3jw5TOPDihydrofolate reductase/0.448
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.448
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.448
3q9zTXQCasein kinase II subunit alpha2.7.11.10.448
3t3r9PLCytochrome P450 2A61.14.130.448
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4ez50RSCyclin-dependent kinase 62.7.11.220.448
4ndnSAMS-adenosylmethionine synthase isoform type-22.5.1.60.448
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.448
5l7dCLRSmoothened homolog/0.448
1ai9NDPDihydrofolate reductase1.5.1.30.447
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.447
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2excJNKMitogen-activated protein kinase 102.7.11.240.447
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
2j0k4STFocal adhesion kinase 12.7.10.20.447
2jf9OHTEstrogen receptor/0.447
2l98STLTroponin C, slow skeletal and cardiac muscles/0.447
2o0uC0MMitogen-activated protein kinase 102.7.11.240.447
2p4yC03Peroxisome proliferator-activated receptor gamma/0.447
2pirDHTAndrogen receptor/0.447
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.447
3bfb9ODPheromone-binding protein ASP1/0.447
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.447
3hub469Mitogen-activated protein kinase 14/0.447
3inwJZBHeat shock protein HSP 90-alpha/0.447
3juhANPCasein kinase II subunit alpha2.7.11.10.447
3ns2PYVAbscisic acid receptor PYL2/0.447
3o73O73Ribosyldihydronicotinamide dehydrogenase [quinone]/0.447
3ox1695Ribosyldihydronicotinamide dehydrogenase [quinone]/0.447
3pejBC2Endoplasmin homolog, putative/0.447
3pm0BHFCytochrome P450 1B1/0.447
3s1dZIRCytokinin dehydrogenase 11.5.99.120.447
3v1nHPK2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase3.7.1.80.447
3vtdTKDVitamin D3 receptor/0.447
4a9hTVPBromodomain-containing protein 2/0.447
4elb34RDihydrofolate reductase/0.447
4f7l0SOCyclin-dependent kinase 82.7.11.220.447
4fkv61KCyclin-dependent kinase 22.7.11.220.447
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.447
4ia3BIVVitamin D3 receptor A/0.447
4ixeIXEDihydrofolate reductase1.5.1.30.447
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.447
4klrCHDFerrochelatase, mitochondrial4.99.1.10.447
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.447
4p6xHCYGlucocorticoid receptor/0.447
4wboANWRhodopsin kinase/0.447
4xe606UDihydrofolate reductase1.5.1.30.447
4yduADPtRNA N6-adenosine threonylcarbamoyltransferase/0.447
4yuqKS1Calmodulin-like domain protein kinase/0.447
5a3bAPRSIR2 family protein/0.447
1dr3HBIDihydrofolate reductase1.5.1.30.446
1ezfIN0Squalene synthase2.5.1.210.446
1s3yTQTDihydrofolate reductase1.5.1.30.446
1tduCB3Thymidylate synthase/0.446
1uyePU9Heat shock protein HSP 90-alpha/0.446
1wvxBD4Death-associated protein kinase 12.7.11.10.446
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.446
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2hqpNDPDihydrofolate reductase1.5.1.30.446
2ittAEEEpidermal growth factor receptor2.7.10.10.446
2nu9COASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.446
2p15EZTEstrogen receptor/0.446
2pvnP63Casein kinase II subunit alpha2.7.11.10.446
3amyAGICasein kinase II subunit alpha2.7.11.10.446
3at4CCKCasein kinase II subunit alpha2.7.11.10.446
3ed1GA3Gibberellin receptor GID1/0.446
3gwfFADCyclohexanone monooxygenase/0.446
3k47D09Dihydrofolate reductase1.5.1.30.446
3o0iP54Heat shock protein HSP 90-alpha/0.446
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3qlrNDPDihydrofolate reductase1.5.1.30.446
3r324CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.446
3r9dX6BCyclin-dependent kinase 22.7.11.220.446
3t1a5MAGag-Pol polyprotein2.7.7.490.446
3vrwYS5Vitamin D3 receptor/0.446
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.446
3vt7VDXVitamin D3 receptor/0.446
3w2o03PEpidermal growth factor receptor2.7.10.10.446
3zsh469Mitogen-activated protein kinase 14/0.446
4bb432WEphrin type-B receptor 42.7.10.10.446
4fgg0U5Dihydrofolate reductase1.5.1.30.446
4jvnYUGEstrogen sulfotransferase2.8.2.40.446
4mwhATPCasein kinase II subunit alpha2.7.11.10.446
4pkl1GHUncharacterized protein/0.446
4qe6JN3Bile acid receptor/0.446
4ruoBIVVitamin D3 receptor A/0.446
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.446
5ikqJMSProstaglandin G/H synthase 21.14.99.10.446
4z9g1Q5Corticotropin-releasing factor receptor 1/0.446
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.445
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1om1IQACasein kinase II subunit alpha2.7.11.10.445
1uykPUXHeat shock protein HSP 90-alpha/0.445
2bilBI1Serine/threonine-protein kinase pim-12.7.11.10.445
2j9lATPH(+)/Cl(-) exchange transporter 5/0.445
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.445
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.445
2qtgMTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 13.2.2.90.445
2tscCB3Thymidylate synthase/0.445
2vagV25Dual specificity protein kinase CLK12.7.12.10.445
2wd9IBPAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.445
2xabVHDHeat shock protein HSP 90-alpha/0.445
2y60M8FIsopenicillin N synthase1.21.3.10.445
2zcePYLPyrrolysine--tRNA ligase/0.445
3a783EVVitamin D3 receptor/0.445
3aidARQGag-Pol polyprotein3.4.23.160.445
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.445
3bv3P39Mitogen-activated protein kinase 14/0.445
3cx5SMACytochrome b/0.445
3fy9XCFDihydrofolate reductase1.5.1.30.445
3ielU5PRibonuclease TTHA02523.10.445
3poz03PEpidermal growth factor receptor2.7.10.10.445
3qqkX02Cyclin-dependent kinase 22.7.11.220.445
3w5rLOAVitamin D3 receptor/0.445
3zuxTCHTransporter/0.445
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
4ez8DHFThymidylate synthase2.1.1.450.445
4gk4L90Ephrin type-A receptor 32.7.10.10.445
4iaq2GM5-hydroxytryptamine receptor 1B/0.445
5d7pOCZNAD-dependent protein deacetylase sirtuin-23.5.10.445
5iu86DZAdenosine receptor A2a/0.445
1bq6COAChalcone synthase 22.3.1.740.444
1dz4CAMCamphor 5-monooxygenase1.14.15.10.444
1f4fTP3Thymidylate synthase/0.444
1j39UPGDNA beta-glucosyltransferase/0.444
1sbrVIBPutative HMP/thiamine-binding protein YkoF/0.444
1sr7MOFProgesterone receptor/0.444
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.444
1zky689Estrogen receptor/0.444
2b37NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2bx8AZQSerum albumin/0.444
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.444
2gqwFADFerredoxin reductase/0.444
2pupADPMethylthioribose kinase2.7.1.1000.444
2q70DC8Estrogen receptor/0.444
2w3wVG9Dihydrofolate reductase/0.444
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.444
2zbaZBATrichothecene 3-O-acetyltransferase/0.444
3dds26BGlycogen phosphorylase, liver form2.4.1.10.444
3e9319BMitogen-activated protein kinase 14/0.444
3ia4MTXDihydrofolate reductase/0.444
3ibqATPPyridoxal kinase/0.444
3imeBZ2Pantothenate synthetase6.3.2.10.444
3inxJZCHeat shock protein HSP 90-alpha/0.444
3jwcEKBDihydrofolate reductase/0.444
3kdiA8SAbscisic acid receptor PYL2/0.444
3o8tBMUMitogen-activated protein kinase 14/0.444
3oyzACOMalate synthase2.3.3.90.444
3qdd94MHeat shock protein HSP 90-alpha/0.444
3s79ASDAromatase1.14.14.140.444
3sp9IL2Peroxisome proliferator-activated receptor delta/0.444
4aotGW8Serine/threonine-protein kinase 102.7.11.10.444
4dsbA8SAbscisic acid receptor PYL3/0.444
4e4qRRHPeroxisome proliferator-activated receptor gamma/0.444
4g8zTOPDihydrofolate reductase1.5.1.30.444
4imoPWZProstaglandin-H2 D-isomerase5.3.99.20.444
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4riyADPEpidermal growth factor receptor2.7.10.10.444
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.444
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.444
5k2aZMAAdenosine receptor A2a/0.444
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.443
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1rx8FOLDihydrofolate reductase1.5.1.30.443
1s3wTQTDihydrofolate reductase1.5.1.30.443
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.443
1xduSFGAclacinomycin 10-hydroxylase RdmB4.1.10.443
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.443
2i51FMNPyridoxamine 5'-phosphate oxidase-related, FMN-binding/0.443
2pogWSTEstrogen receptor/0.443
2ydwWSHBromodomain-containing protein 2/0.443
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.443
3d78NBBPheromone-binding protein ASP1/0.443
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3hz142CHeat shock protein HSP 90-alpha/0.443
3igoANPCalmodulin-domain protein kinase 1, putative/0.443
3oafOAGDihydrofolate reductase1.5.1.30.443
3p7nFMNLight-activated DNA-binding protein EL222/0.443
3rps4B0Casein kinase II subunit alpha2.7.11.10.443
3upjU03Gag-Pol polyprotein/0.443
3vquO22Dual specificity protein kinase TTK2.7.12.10.443
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.443
4g95OAGDihydrofolate reductase1.5.1.30.443
4inb1F6Gag protein/0.443
4j6cSTRCytochrome P450 monooxygenase/0.443
4jlj1NMDeoxycytidine kinase2.7.1.740.443
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
4lsjLSJGlucocorticoid receptor/0.443
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.443
4ug71EVNitric oxide synthase oxygenase1.14.13.1650.443
4x5fFOLDihydrofolate reductase1.5.1.30.443
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.443
1dhiMTXDihydrofolate reductase1.5.1.30.442
1kl2FONSerine hydroxymethyltransferase/0.442
1l2iETCEstrogen receptor/0.442
1uy6PU3Heat shock protein HSP 90-alpha/0.442
1uydPU8Heat shock protein HSP 90-alpha/0.442
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
2cig1DGDihydrofolate reductase1.5.1.30.442
2f2cAP9Cyclin-dependent kinase 62.7.11.220.442
2gjnFMNNitronate monooxygenase1.13.12.160.442
2hc4VDXVitamin D3 receptor A/0.442
2jfaRALEstrogen receptor/0.442
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.442
2pulACPMethylthioribose kinase2.7.1.1000.442
2q9fC3SCholesterol 24-hydroxylase/0.442
2qo9ANPEphrin type-A receptor 32.7.10.10.442
2xir00JVascular endothelial growth factor receptor 22.7.10.10.442
2yemWSHBromodomain-containing protein 4/0.442
2yjxYJXHeat shock protein HSP 90-alpha/0.442
2zlaVDBVitamin D3 receptor/0.442
2zlcVDXVitamin D3 receptor/0.442
3c3eFO12-phospho-L-lactate transferase/0.442
3l70JZVCytochrome b/0.442
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.442
3p3zP3ZPutative cytochrome P450/0.442
3srrQ20Dihydrofolate reductase1.5.1.30.442
3uvvREARetinoic acid receptor RXR-alpha/0.442
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.442
3zvvXAZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.442
4a9e3PFBromodomain-containing protein 2/0.442
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.442
4eoi1ROCyclin-dependent kinase 22.7.11.220.442
4gqiM49Ribosyldihydronicotinamide dehydrogenase [quinone]/0.442
4h9753SDihydrofolate reductase1.5.1.30.442
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.442
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.442
4jqeANPCasein kinase II subunit alpha2.7.11.10.442
4jrvKJVEpidermal growth factor receptor2.7.10.10.442
4xldBRLPeroxisome proliferator-activated receptor gamma/0.442
5dq8FLFTranscriptional enhancer factor TEF-4/0.442
1axwMTXThymidylate synthase/0.441
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1lriCLRBeta-elicitin cryptogein/0.441
1pp9SMACytochrome b/0.441
1uyfPU1Heat shock protein HSP 90-alpha/0.441
1zeoC01Peroxisome proliferator-activated receptor gamma/0.441
1zz2B11Mitogen-activated protein kinase 14/0.441
2hk51BMTyrosine-protein kinase HCK2.7.10.20.441
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2p7zOHTEstrogen-related receptor gamma/0.441
2po7CHDFerrochelatase, mitochondrial4.99.1.10.441
2uzeC95Cyclin-dependent kinase 22.7.11.220.441
2wotZZGTGF-beta receptor type-12.7.11.300.441
2y6o1N1Ephrin type-A receptor 42.7.10.10.441
2yiuSMACytochrome b/0.441
3cgbCOACoenzyme A disulfide reductase/0.441
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3cv9VDXVitamin D3 dihydroxylase/0.441
3fi3JK2Mitogen-activated protein kinase 102.7.11.240.441
3gfbNADL-threonine 3-dehydrogenase/0.441
3h1jSMACytochrome b/0.441
3ictFADCoenzyme A disulfide reductase/0.441
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3o6o94MHeat shock protein 83/0.441
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.441
4bqg50QHeat shock protein HSP 90-alpha/0.441
4dgmAGICasein kinase II subunit alpha2.7.11.10.441
4g2h0VQVitamin D3 receptor A/0.441
4l9q9TPSerum albumin/0.441
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.441
4nc3ERM5-hydroxytryptamine receptor 2B/0.441
4q0a4OAVitamin D3 receptor A/0.441
4ug7H4BNitric oxide synthase oxygenase1.14.13.1650.441
1hk2T44Serum albumin/0.440
1ie4T44Transthyretin/0.440
1rx7FOLDihydrofolate reductase1.5.1.30.440
1sqvUHDCytochrome b/0.440
1tlcF89Thymidylate synthase/0.440
2aclREARetinoic acid receptor RXR-alpha/0.440
2c96ATPPsp operon transcriptional activator/0.440
2ewaSB2Mitogen-activated protein kinase 14/0.440
2harOCCVitamin D3 receptor/0.440
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2v1aFMNNPH1-1/0.440
2vf0F89Thymidylate synthase/0.440
2vwx7X4Ephrin type-B receptor 42.7.10.10.440
2wi72KLHeat shock protein HSP 90-alpha/0.440
2x7gPVBSRSF protein kinase 22.7.11.10.440
2yeiXQIHeat shock protein HSP 90-alpha/0.440
2znq401Peroxisome proliferator-activated receptor delta/0.440
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.440
3ddw055Glycogen phosphorylase, liver form2.4.1.10.440
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.440
3gwfNAPCyclohexanone monooxygenase/0.440
3lpkZ76Beta-secretase 13.4.23.460.440
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440
3tk3CPZCytochrome P450 2B41.14.14.10.440
3v1s0LHStrictosidine synthase4.3.3.20.440
3w5tLHPVitamin D3 receptor/0.440
3wiyLC6Induced myeloid leukemia cell differentiation protein Mcl-1/0.440
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.440
4b1fKRHGlutamate racemase/0.440
4bfrJ82Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform2.7.1.1530.440
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.440
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.440
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.440
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.440
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.440
4jr3KJREpidermal growth factor receptor2.7.10.10.440
4olm198Androgen receptor/0.440
4zvmDM2Ribosyldihydronicotinamide dehydrogenase [quinone]/0.440