sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1s0x | C3S | Nuclear receptor ROR-alpha |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 1.000 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.699 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.512 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.511 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.478 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.449 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.444 |