sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1r6g | 442 | Thyroid hormone receptor beta |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1r6g | 442 | Thyroid hormone receptor beta | / | 1.000 | |
| 1q4x | G24 | Thyroid hormone receptor beta | / | 0.584 | |
| 1nq1 | 4HY | Thyroid hormone receptor beta | / | 0.533 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.503 | |
| 2pin | 4HY | Thyroid hormone receptor beta | / | 0.496 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.496 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.491 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.486 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.485 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.483 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.482 | |
| 3d57 | 4HY | Thyroid hormone receptor beta | / | 0.481 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.481 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.481 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.481 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.481 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.480 | |
| 2z6j | TUI | 2-nitropropane dioxygenase | / | 0.479 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.477 | |
| 1osv | CHC | Bile acid receptor | / | 0.476 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.476 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.476 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.476 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.475 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.475 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.474 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.474 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.473 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.472 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.472 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.471 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.470 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.470 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.470 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.470 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.470 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.469 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.469 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.469 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.469 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.469 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.468 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.468 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 2zbz | VDX | Vitamin D3 dihydroxylase | / | 0.467 | |
| 3vso | EK1 | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.467 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.467 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.466 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.466 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.466 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.465 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.465 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.465 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.465 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.465 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.465 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.464 | |
| 1q4t | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.464 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.464 | |
| 3vsp | EK8 | Peroxisome proliferator-activated receptor gamma | / | 0.464 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.463 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.463 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.463 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.463 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.462 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.462 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.462 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.462 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.462 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.462 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.461 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.461 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.461 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.461 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.461 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.460 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.460 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.460 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.460 | |
| 4i3v | NAD | Aldehyde dehydrogenase (NAD+) | / | 0.460 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.460 | |
| 4uya | AGS | Mitogen-activated protein kinase kinase kinase 21 | 2.7.11.25 | 0.460 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.459 | |
| 1olm | VTQ | SEC14-like protein 2 | / | 0.459 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.459 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.459 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.459 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.459 | |
| 3inx | JZC | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.459 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.458 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.458 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.458 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.458 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.458 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.458 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.458 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 1fml | RTL | Retinol dehydratase | / | 0.457 | |
| 1nq2 | 4HY | Thyroid hormone receptor beta | / | 0.457 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.457 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.457 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.457 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.457 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.457 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3r7c | FAD | FAD-linked sulfhydryl oxidase ALR | 1.8.3.2 | 0.457 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.457 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.457 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.457 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.456 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.456 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.456 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 2p4y | C03 | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.456 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.456 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.456 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.456 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.456 | |
| 4l98 | LRG | Peroxisome proliferator-activated receptor gamma | / | 0.456 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.456 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.455 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.455 | |
| 2c7x | NRB | Cytochrome P450 monooxygenase PikC | / | 0.455 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.455 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.455 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.455 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.455 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.455 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.455 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 1uyr | D1L | Acetyl-CoA carboxylase | / | 0.454 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.454 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.454 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.454 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.454 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.454 | |
| 4l4x | NDP | AmphI | / | 0.454 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.453 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 3oqu | A8S | Abscisic acid receptor PYL9 | / | 0.453 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.453 | |
| 3zk5 | Z18 | Cytochrome P450 monooxygenase PikC | / | 0.453 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.453 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.452 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.452 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1q4u | 4CA | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.452 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.452 | |
| 2aib | ERG | Beta-elicitin cinnamomin | / | 0.452 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.452 | |
| 2j3k | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.452 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.452 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.452 | |
| 4awq | 592 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.452 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.451 | |
| 1nax | IH5 | Thyroid hormone receptor beta | / | 0.451 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.451 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.451 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.451 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.451 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.451 | |
| 4l8u | 9AZ | Serum albumin | / | 0.451 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.450 | |
| 1iep | STI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.450 | |
| 2uxi | G50 | HTH-type transcriptional regulator TtgR | / | 0.450 | |
| 2xvv | 9DN | Serum albumin | / | 0.450 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.450 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.450 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.450 | |
| 3e5r | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.450 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.450 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.450 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.450 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.450 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 4l9q | 9TP | Serum albumin | / | 0.450 | |
| 1eio | GCH | Gastrotropin | / | 0.449 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.449 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.449 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.449 | |
| 1g67 | TZP | Thiamine-phosphate synthase | / | 0.448 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.448 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.448 | |
| 1soz | VAL_TYR_GLN_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.448 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2xvw | 9NR | Serum albumin | / | 0.448 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.448 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.448 | |
| 3glm | COO | Glutaconyl-CoA decarboxylase alpha subunit | / | 0.448 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.448 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.448 | |
| 4gkv | NAD | Alcohol dehydrogenase, propanol-preferring | 1.1.1.1 | 0.448 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.448 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.447 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.447 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.447 | |
| 2q5p | 241 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3ii4 | 3II | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.447 | |
| 3pj8 | 404 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3r32 | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.447 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.447 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4rrx | LUR | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.447 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 1nav | IH5 | Thyroid hormone receptor alpha | / | 0.446 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.446 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.446 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.446 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.446 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3vjh | J35 | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4iah | 1DX | Alr2278 protein | / | 0.446 | |
| 4neu | Q1A | Receptor-interacting serine/threonine-protein kinase 1 | 2.7.11.1 | 0.446 | |
| 4zow | CLM | Multidrug transporter MdfA | / | 0.446 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.446 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.445 | |
| 2q6s | PLB | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 3cgo | JNO | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.445 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.445 | |
| 3ey9 | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.445 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.445 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.445 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.445 | |
| 3w33 | W19 | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.445 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.445 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.445 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.444 | |
| 1pow | FAD | Pyruvate oxidase | 1.2.3.3 | 0.444 | |
| 2ca0 | PXI | Cytochrome P450 monooxygenase PikC | / | 0.444 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.444 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.444 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.444 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 3up3 | XCA | aceDAF-12 | / | 0.444 | |
| 4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.444 | |
| 4b7d | QLE | Cytochrome P450 monooxygenase PikC | / | 0.444 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.444 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.444 | |
| 5c7o | NAD | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | 1.2.1.12 | 0.444 | |
| 1e7a | PFL | Serum albumin | / | 0.443 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.443 | |
| 1jut | LYD | Thymidylate synthase | / | 0.443 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.443 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.443 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.443 | |
| 3n7u | NAD | Formate dehydrogenase, chloroplastic/mitochondrial | / | 0.443 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.443 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.443 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3zsi | 52P | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.443 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.443 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1heu | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1ml6 | GBX | Glutathione S-transferase A2 | 2.5.1.18 | 0.442 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.442 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.442 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.441 | |
| 1n46 | PFA | Thyroid hormone receptor beta | / | 0.441 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.441 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.441 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2dsh | SAH | Diphthine synthase | / | 0.441 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.441 | |
| 3anl | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.441 | |
| 3hv5 | R24 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3vev | 0H4 | Glucokinase | 2.7.1.2 | 0.441 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.441 | |
| 4id7 | 1G0 | Activated CDC42 kinase 1 | / | 0.441 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.441 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.440 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.440 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.440 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.440 | |
| 1r0e | DFN | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1sn5 | T3 | Transthyretin | / | 0.440 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.440 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.440 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.440 | |
| 3q7d | NPX | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.440 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4b1f | KRH | Glutamate racemase | / | 0.440 | |
| 4g3e | 0WC | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.440 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.440 | |
| 4lva | 20M | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.440 | |
| 4o59 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.440 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.440 |