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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.62

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.621.000
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.704
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.613
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.613
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.556
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.549
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.544
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.519
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.512
2zbaZBATrichothecene 3-O-acetyltransferase/0.511
1equEQIEstradiol 17-beta-dehydrogenase 11.1.1.620.504
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.496
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.496
4a8v2ANMajor pollen allergen Bet v 1-J/0.495
1cbqRE9Cellular retinoic acid-binding protein 2/0.493
3h3r14HCollagen type IV alpha-3-binding protein/0.492
4g95OAGDihydrofolate reductase1.5.1.30.491
1x8lOXRRetinol dehydratase/0.489
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.487
3gfbNADL-threonine 3-dehydrogenase/0.483
5hs1VORLanosterol 14-alpha demethylase/0.483
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.481
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.479
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.478
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.478
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.477
1fm4DXCMajor pollen allergen Bet v 1-L/0.476
1pd9CO4Dihydrofolate reductase1.5.1.30.476
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.476
2pg0FADAcyl-CoA dehydrogenase/0.476
2ejvNADL-threonine 3-dehydrogenase/0.475
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.475
1obnASVIsopenicillin N synthase1.21.3.10.474
1s3uTQDDihydrofolate reductase1.5.1.30.474
4la7A1OAbscisic acid receptor PYL2/0.474
3s3vTOPDihydrofolate reductase1.5.1.30.473
4rrrA3TThreonine--tRNA ligase6.1.1.30.473
3ixp834Ecdysone receptor/0.472
4a87NARMajor pollen allergen Bet v 1-A/0.472
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.471
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.471
4pleCPSNuclear receptor subfamily 5 group A member 2/0.471
2po7CHDFerrochelatase, mitochondrial4.99.1.10.470
2yoj8Y6Genome polyprotein2.7.7.480.470
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.470
4ie6UN9Alpha-ketoglutarate-dependent dioxygenase FTO/0.470
4nbwNADShort-chain dehydrogenase/reductase SDR/0.470
4uymVOR14-alpha sterol demethylase Cyp51B/0.470
3ibqATPPyridoxal kinase/0.469
3tqaNDPDihydrofolate reductase/0.469
4bfxZVXPantothenate kinase2.7.1.330.469
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.469
1h51FMNPentaerythritol tetranitrate reductase/0.468
1in5ADPHolliday junction ATP-dependent DNA helicase RuvB/0.468
3elm24FCollagenase 33.4.240.468
3oafOAGDihydrofolate reductase1.5.1.30.468
2c9zQUEAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.467
4a802ANMajor pollen allergen Bet v 1-A/0.467
1mvtDTMDihydrofolate reductase1.5.1.30.466
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.466
3lqfNADGalactitol dehydrogenase/0.466
3nmpPYVAbscisic acid receptor PYL2/0.466
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
2bxqIMNSerum albumin/0.465
2e9dB76Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.465
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.465
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.465
4a862ANMajor pollen allergen Bet v 1-A/0.465
1yvfPH7Polyprotein/0.464
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.464
2ok7FADFerredoxin--NADP reductase, apicoplast/0.464
2xvv9DNSerum albumin/0.464
3wv9FEGHmd co-occurring protein HcgE/0.464
4a83DXCMajor pollen allergen Bet v 1-A/0.464
4oztP1AEcdysone receptor, putative/0.464
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.463
3c1oNAPEugenol synthase/0.463
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.463
1kqoDNDNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.462
1v35NAIEnoyl-ACP reductase/0.462
2dfvNADL-threonine 3-dehydrogenase/0.462
2g78REACellular retinoic acid-binding protein 2/0.462
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.462
2ohvNHLGlutamate racemase/0.462
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
3p3zP3ZPutative cytochrome P450/0.462
4l1xNAPAldo-keto reductase family 1 member C2/0.462
1fmjRTLRetinol dehydratase/0.461
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.461
1h73ANPHomoserine kinase2.7.1.390.461
3h3t16HCollagen type IV alpha-3-binding protein/0.461
1dr3TAPDihydrofolate reductase1.5.1.30.460
1h50FMNPentaerythritol tetranitrate reductase/0.460
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.460
1sxjAGSReplication factor C subunit 1/0.460
3h3sH15Collagen type IV alpha-3-binding protein/0.460
4a81DXCMajor pollen allergen Bet v 1-A/0.460
4a86H35Major pollen allergen Bet v 1-A/0.460
4ie0PD2Alpha-ketoglutarate-dependent dioxygenase FTO/0.460
2bxmIMNSerum albumin/0.459
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.459
2xvw9NRSerum albumin/0.459
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
5a3bAPRSIR2 family protein/0.459
2jn3JN3Fatty acid-binding protein, liver/0.458
2w3bNDPDihydrofolate reductase1.5.1.30.458
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.458
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.458
4gukP2GNeuronal calcium sensor 1/0.458
4k6fNAPPutative Acetoacetyl-CoA reductase/0.458
1cqp803Integrin alpha-L/0.457
1mr9ACOStreptogramin A acetyltransferase2.3.10.457
2dhfDZFDihydrofolate reductase1.5.1.30.457
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
3c3xNAPEugenol synthase 11.1.1.3180.457
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
1x1cSAHC-20 methyltransferase/0.456
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.456
1h36R88Squalene--hopene cyclase4.2.1.1290.455
1osvCHCBile acid receptor/0.455
1rd4L08Integrin alpha-L/0.455
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3hllI45Mitogen-activated protein kinase 14/0.455
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
4nvk2NYPeroxidase/0.455
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.454
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.454
3tydXHPDihydropteroate synthase/0.454
4a84DXCMajor pollen allergen Bet v 1-A/0.454
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.454
4j0t6T9Beta-secretase 13.4.23.460.454
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.454
4uugPXGBranched-chain amino acid aminotransferase, putative/0.454
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.453
2gv8NDPThiol-specific monooxygenase1.14.130.453
2qimZEAClass 10 plant pathogenesis-related protein/0.453
2rhrEMOPutative ketoacyl reductase1.3.10.453
3d84NDPDihydrofolate reductase1.5.1.30.453
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.453
3n0hTOPDihydrofolate reductase1.5.1.30.453
3p62FMNPentaerythritol tetranitrate reductase/0.453
4ejmNAPPutative zinc-binding dehydrogenase/0.453
4m83ERYOleandomycin glycosyltransferase2.4.10.453
5k2bZMAAdenosine receptor A2a/0.453
1trgCB3Thymidylate synthase/0.452
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.452
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.452
3gwfNAPCyclohexanone monooxygenase/0.452
4bj9UHBTankyrase-22.4.2.300.452
4jicFMNGTN Reductase/0.452
4qzuRTLRetinol-binding protein 2/0.452
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.451
1ykdCMPAdenylate cyclase/0.451
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.451
3br3ETHTH-type transcriptional regulator QacR/0.451
3eej53RUncharacterized protein/0.451
3fznD7KBenzoylformate decarboxylase4.1.1.70.451
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.451
5bt42LOBromodomain-containing protein 4/0.451
5k2cZMAAdenosine receptor A2a/0.451
1dhfFOLDihydrofolate reductase1.5.1.30.450
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.450
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.450
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.450
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.450
2e0nSAHPrecorrin-2 C20-methyltransferase/0.450
2fznFADBifunctional protein PutA1.5.5.20.450
2ghlLIBMitogen-activated protein kinase 14/0.450
3qj0QI3Botulinum neurotoxin type A3.4.24.690.450
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
4m9aFDAAcyl-CoA dehydrogenase/0.450
1g45FSBCarbonic anhydrase 24.2.1.10.449
1gqyACPUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.449
1kr2TADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.449
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.449
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.449
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.449
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.449
3fr5I4AFatty acid-binding protein, adipocyte/0.449
3ns2PYVAbscisic acid receptor PYL2/0.449
3ukuC69Actin-related protein 3/0.449
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.449
4x5gFOLDihydrofolate reductase1.5.1.30.449
5dhgDGVNociceptin receptor/0.449
1t7o152Carnitine O-acetyltransferase2.3.1.70.448
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.448
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.448
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3s1dZIRCytokinin dehydrogenase 11.5.99.120.448
3up0D7SaceDAF-12/0.448
3zoiM2WIsopenicillin N synthase1.21.3.10.448
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.448
4g3jVNTLanosterol 14-alpha-demethylase/0.448
4imoPWZProstaglandin-H2 D-isomerase5.3.99.20.448
4o1mNADEnoyl-acyl carrier reductase/0.448
1fmlRTLRetinol dehydratase/0.447
1o76CAMCamphor 5-monooxygenase1.14.15.10.447
2b53D23Cyclin-dependent kinase 22.7.11.220.447
2jfz003Glutamate racemase/0.447
2rh9IGPTryptophan synthase alpha chain/0.447
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.447
3hbbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
3jt3H4BNitric oxide synthase, brain1.14.13.390.447
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.447
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.447
4a6rTA8Probable aminotransferase/0.447
4q73FADBifunctional protein PutA/0.447
4v12POGMaoC like domain protein/0.447
5a3cNADSIR2 family protein/0.447
5c1mCLRMu-type opioid receptor/0.447
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
1vyrFMNPentaerythritol tetranitrate reductase/0.446
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2iyfERYOleandomycin glycosyltransferase2.4.10.446
2rlcCHDCholoylglycine hydrolase3.5.1.240.446
3gwdNAPCyclohexanone monooxygenase/0.446
3junAKDPhenazine biosynthesis protein A/B/0.446
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
3qizQI2Botulinum neurotoxin type A3.4.24.690.446
3v2uATPProtein GAL3/0.446
4a31MYAGlycylpeptide N-tetradecanoyltransferase/0.446
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4pzrCOAHistone acetyltransferase p300/0.446
4q0kGA3Phytohormone-binding protein/0.446
4wecNADShort chain dehydrogenase/0.446
4zs2FLUAlpha-ketoglutarate-dependent dioxygenase FTO/0.446
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.445
1nvtNAPShikimate dehydrogenase (NADP(+))/0.445
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.445
1xe65FPPlasmepsin-23.4.23.390.445
2abbFMNPentaerythritol tetranitrate reductase/0.445
2cbsR13Cellular retinoic acid-binding protein 2/0.445
2he5NDPAldo-keto reductase family 1 member C211.1.10.445
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2znq401Peroxisome proliferator-activated receptor delta/0.445
2zynBCDPeriplasmic binding protein/0.445
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3own3OWRenin3.4.23.150.445
3p84FMNPentaerythritol tetranitrate reductase/0.445
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.445
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.445
4iteTEYVitamin D3 receptor/0.445
4jq3NAPAldo-keto reductase family 1 member C2/0.445
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.445
4psbGA3Cytokinin-specific binding protein/0.445
4rrgA3TThreonine--tRNA ligase6.1.1.30.445
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.445
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
5irnADPNucleotide binding oligomerization domain containing 2/0.445
1c7oPPGHemolysin/0.444
1drhNAPDihydrofolate reductase1.5.1.30.444
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.444
1qm5PLPMaltodextrin phosphorylase2.4.1.10.444
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.444
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.444
3djfBC3Purine nucleoside phosphorylase/0.444
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
3t3r9PLCytochrome P450 2A61.14.130.444
3u9eCOALmo1369 protein/0.444
4b4w9L9Bifunctional protein FolD/0.444
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4tjy3GNTankyrase-22.4.2.300.444
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.444
5a0112VO-glycosyltransferase/0.444
3sn6P0GBeta-2 adrenergic receptor/0.444
1dg8NDPDihydrofolate reductase1.5.1.30.443
1dyjDDFDihydrofolate reductase1.5.1.30.443
1hb1OCVIsopenicillin N synthase1.21.3.10.443
1mrqSTRAldo-keto reductase family 1 member C1/0.443
1mvsDTMDihydrofolate reductase1.5.1.30.443
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.443
1qjfACSIsopenicillin N synthase1.21.3.10.443
1rszDIHPurine nucleoside phosphorylase2.4.2.10.443
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.443
2rqfJH3Hemolymph juvenile hormone binding protein/0.443
3antS82Bifunctional epoxide hydrolase 23.3.2.100.443
3b9lAZZSerum albumin/0.443
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
3c14FOKAdenylate cyclase type 2/0.443
3c14FOKAdenylate cyclase type 5/0.443
3cbsR12Cellular retinoic acid-binding protein 2/0.443
3gggNADPrephenate dehydrogenase/0.443
3l63CAMCamphor 5-monooxygenase1.14.15.10.443
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.443
3to6LYS_CMCHistone acetyltransferase ESA1/0.443
4dbzNDPPutative ketoacyl reductase1.3.10.443
4q71FADBifunctional protein PutA/0.443
1ai9NDPDihydrofolate reductase1.5.1.30.442
1bk0ACVIsopenicillin N synthase1.21.3.10.442
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
1diuBDMDihydrofolate reductase1.5.1.30.442
1dyhDZFDihydrofolate reductase1.5.1.30.442
1jolFFODihydrofolate reductase1.5.1.30.442
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.442
1tj0FADBifunctional protein PutA1.5.5.20.442
1tysTMPThymidylate synthase/0.442
1zg32HIIsoflavone 4'-O-methyltransferase/0.442
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.442
2g226IGRenin3.4.23.150.442
3b4fTUOCarbonic anhydrase 24.2.1.10.442
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.442
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.442
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.442
3qiyQI1Botulinum neurotoxin type A3.4.24.690.442
3qt62P0Mevalonate diphosphate decarboxylase/0.442
3tm5SFGUncharacterized protein/0.442
4cukNAID-lactate dehydrogenase/0.442
4i13FOLDihydrofolate reductase1.5.1.30.442
4m6jNDPDihydrofolate reductase1.5.1.30.442
4nmdFDABifunctional protein PutA/0.442
4q72FADBifunctional protein PutA/0.442
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.442
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.441
1txtCAAHMG-CoA synthase/0.441
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2ea2F77Methionine aminopeptidase 2/0.441
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.441
2wu4HBPAcetylcholinesterase3.1.1.70.441
3b9oFMNAlkane monoxygenase/0.441
3h0bB35Beta-secretase 13.4.23.460.441
3imgBZ2Pantothenate synthetase6.3.2.10.441
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.441
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.441
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.441
4ipw1G7Mycocyclosin synthase1.14.21.90.441
4mv1ADPBiotin carboxylase6.3.4.140.441
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.441
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
1draMTXDihydrofolate reductase1.5.1.30.440
1h62ANBPentaerythritol tetranitrate reductase/0.440
1o1vTCHGastrotropin/0.440
1ra8FOLDihydrofolate reductase1.5.1.30.440
2akoADPGlutamate 5-kinase/0.440
2g1r3IGRenin3.4.23.150.440
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2om9AJAPeroxisome proliferator-activated receptor gamma/0.440
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.440
2vbpVB1Isopenicillin N synthase1.21.3.10.440
3aosJH2Hemolymph juvenile hormone binding protein/0.440
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.440
3eldSFGMethyltransferase/0.440
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.440
4hxyNDPPlm1/0.440
4iarERM5-hydroxytryptamine receptor 1B/0.440
4kkyCAMCamphor 5-monooxygenase1.14.15.10.440
4li81XQTankyrase-12.4.2.300.440
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.440
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.440
5iubCLRAdenosine receptor A2a/0.440
5dhhDGWNociceptin receptor/0.440