sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1qsn | COA | HAT A1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1qsn | COA | HAT A1 | / | 1.000 | |
| 1pua | COA | HAT A1 | / | 0.578 | |
| 1pu9 | COA | HAT A1 | / | 0.518 | |
| 1cm0 | COA | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.468 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.461 | |
| 3v2u | ATP | Protein GAL3 | / | 0.453 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.451 | |
| 2ejz | SAH | Diphthine synthase | / | 0.449 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.445 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.445 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 3hxd | BD7 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.442 |