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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1pxmCK5Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1pxmCK5Cyclin-dependent kinase 22.7.11.221.000
4fkq42KCyclin-dependent kinase 22.7.11.220.550
3lfnA27Cyclin-dependent kinase 22.7.11.220.537
3r8lZ30Cyclin-dependent kinase 22.7.11.220.527
3qzgX67Cyclin-dependent kinase 22.7.11.220.509
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.503
2c6o4SPCyclin-dependent kinase 22.7.11.220.500
4ek610KCyclin-dependent kinase 22.7.11.220.491
3s1h56ZCyclin-dependent kinase 22.7.11.220.485
2btrU73Cyclin-dependent kinase 22.7.11.220.484
1ke5LS1Cyclin-dependent kinase 22.7.11.220.478
3qtuX44Cyclin-dependent kinase 22.7.11.220.477
4fkt48KCyclin-dependent kinase 22.7.11.220.477
1gii1PUCyclin-dependent kinase 22.7.11.220.476
3rni21ZCyclin-dependent kinase 22.7.11.220.472
2a0cCK9Cyclin-dependent kinase 22.7.11.220.470
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.469
2r3jSCJCyclin-dependent kinase 22.7.11.220.467
2btsU32Cyclin-dependent kinase 22.7.11.220.463
3r8vZ62Cyclin-dependent kinase 22.7.11.220.463
2xmyCDKCyclin-dependent kinase 22.7.11.220.462
1ykr628Cyclin-dependent kinase 22.7.11.220.461
2vthLZ2Cyclin-dependent kinase 22.7.11.220.461
3rjc06ZCyclin-dependent kinase 22.7.11.220.459
1gih1PUCyclin-dependent kinase 22.7.11.220.456
4fki09KCyclin-dependent kinase 22.7.11.220.455
1oitHDTCyclin-dependent kinase 22.7.11.220.454
1v1k3FPCyclin-dependent kinase 22.7.11.220.453
3sw719KCyclin-dependent kinase 22.7.11.220.453
3qqhX0ACyclin-dependent kinase 22.7.11.220.452
3r7yZ04Cyclin-dependent kinase 22.7.11.220.452
3rpv26ZCyclin-dependent kinase 22.7.11.220.452
3lfqA28Cyclin-dependent kinase 22.7.11.220.451
4fkpLS5Cyclin-dependent kinase 22.7.11.220.451
3r9dX6BCyclin-dependent kinase 22.7.11.220.448
3r1yX76Cyclin-dependent kinase 22.7.11.220.447
3rak03ZCyclin-dependent kinase 22.7.11.220.447
1p2a5BNCyclin-dependent kinase 22.7.11.220.446
2w06FRVCyclin-dependent kinase 22.7.11.220.446
3rkb12ZCyclin-dependent kinase 22.7.11.220.446
3r83Z14Cyclin-dependent kinase 22.7.11.220.445
4fkg4CKCyclin-dependent kinase 22.7.11.220.445
3qxoX65Cyclin-dependent kinase 22.7.11.220.444
1w8cN69Cyclin-dependent kinase 22.7.11.220.443
1pxoCK7Cyclin-dependent kinase 22.7.11.220.442
4bgh3I6Cyclin-dependent kinase 22.7.11.220.442
3sw418KCyclin-dependent kinase 22.7.11.220.441