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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1pg2ADNMethionine--tRNA ligase6.1.1.10

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1pg2ADNMethionine--tRNA ligase6.1.1.101.000
1pfyMSPMethionine--tRNA ligase6.1.1.100.587
1pg0MODMethionine--tRNA ligase6.1.1.100.542
4c36ZO9cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
2f3eAXQBeta-secretase 13.4.23.460.447
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.447
3pbzF02Endothiapepsin3.4.23.220.445
3ivcFG4Pantothenate synthetase6.3.2.10.442
3ak4NADNADH-dependent quinuclidinone reductase/0.440