Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1p2a5BNCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1p2a5BNCyclin-dependent kinase 22.7.11.221.000
1v1k3FPCyclin-dependent kinase 22.7.11.220.625
2btsU32Cyclin-dependent kinase 22.7.11.220.603
1oiqHDUCyclin-dependent kinase 22.7.11.220.584
2vthLZ2Cyclin-dependent kinase 22.7.11.220.576
1gih1PUCyclin-dependent kinase 22.7.11.220.573
2btrU73Cyclin-dependent kinase 22.7.11.220.571
2w1hL0FCyclin-dependent kinase 22.7.11.220.568
1pxmCK5Cyclin-dependent kinase 22.7.11.220.564
3rak03ZCyclin-dependent kinase 22.7.11.220.561
1pxoCK7Cyclin-dependent kinase 22.7.11.220.554
3sqq99ZCyclin-dependent kinase 22.7.11.220.554
3ezvEZVCyclin-dependent kinase 22.7.11.220.551
3rni21ZCyclin-dependent kinase 22.7.11.220.551
2c6o4SPCyclin-dependent kinase 22.7.11.220.550
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.550
4bgh3I6Cyclin-dependent kinase 22.7.11.220.548
3qxoX65Cyclin-dependent kinase 22.7.11.220.547
3qzgX67Cyclin-dependent kinase 22.7.11.220.546
3rm719ZCyclin-dependent kinase 22.7.11.220.546
4fkt48KCyclin-dependent kinase 22.7.11.220.545
3qtuX44Cyclin-dependent kinase 22.7.11.220.544
3qqkX02Cyclin-dependent kinase 22.7.11.220.543
3qtxX43Cyclin-dependent kinase 22.7.11.220.543
4ek610KCyclin-dependent kinase 22.7.11.220.537
2vv9IM9Cyclin-dependent kinase 22.7.11.220.536
2r3kSCQCyclin-dependent kinase 22.7.11.220.535
3rmf20ZCyclin-dependent kinase 22.7.11.220.534
2w06FRVCyclin-dependent kinase 22.7.11.220.533
3rpy27ZCyclin-dependent kinase 22.7.11.220.533
2c69CT8Cyclin-dependent kinase 22.7.11.220.530
4fkpLS5Cyclin-dependent kinase 22.7.11.220.529
3s1h56ZCyclin-dependent kinase 22.7.11.220.527
3qtzX42Cyclin-dependent kinase 22.7.11.220.526
3rk909ZCyclin-dependent kinase 22.7.11.220.526
3ral04ZCyclin-dependent kinase 22.7.11.220.525
2c6iDT1Cyclin-dependent kinase 22.7.11.220.524
3r9hZ67Cyclin-dependent kinase 22.7.11.220.524
4ez30S0Cyclin-dependent kinase 22.7.11.220.524
4fx360KCyclin-dependent kinase 22.7.11.220.524
3iggEFQCyclin-dependent kinase 22.7.11.220.523
3raiX85Cyclin-dependent kinase 22.7.11.220.522
1oitHDTCyclin-dependent kinase 22.7.11.220.521
4fkr45KCyclin-dependent kinase 22.7.11.220.521
1w0xOLOCyclin-dependent kinase 22.7.11.220.520
3rjc06ZCyclin-dependent kinase 22.7.11.220.520
3ti1B49Cyclin-dependent kinase 22.7.11.220.520
3qxpX64Cyclin-dependent kinase 22.7.11.220.519
2bhhRYUCyclin-dependent kinase 22.7.11.220.517
2xmyCDKCyclin-dependent kinase 22.7.11.220.517
3r7yZ04Cyclin-dependent kinase 22.7.11.220.516
3rk708ZCyclin-dependent kinase 22.7.11.220.515
1ckpPVBCyclin-dependent kinase 22.7.11.220.514
1fvv107Cyclin-dependent kinase 22.7.11.220.514
3fz1B98Cyclin-dependent kinase 22.7.11.220.514
3r9dX6BCyclin-dependent kinase 22.7.11.220.514
3rpv26ZCyclin-dependent kinase 22.7.11.220.514
2uzoC62Cyclin-dependent kinase 22.7.11.220.511
3qqfX07Cyclin-dependent kinase 22.7.11.220.511
3r71X86Cyclin-dependent kinase 22.7.11.220.511
4fkg4CKCyclin-dependent kinase 22.7.11.220.511
1y91CT9Cyclin-dependent kinase 22.7.11.220.510
4fko20KCyclin-dependent kinase 22.7.11.220.510
4fkq42KCyclin-dependent kinase 22.7.11.220.510
1g5sI17Cyclin-dependent kinase 22.7.11.220.509
3r73X87Cyclin-dependent kinase 22.7.11.220.508
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.506
1ke9LS5Cyclin-dependent kinase 22.7.11.220.504
2r3lSCWCyclin-dependent kinase 22.7.11.220.504
3r7uX96Cyclin-dependent kinase 22.7.11.220.504
3rk507ZCyclin-dependent kinase 22.7.11.220.504
3s2pPMUCyclin-dependent kinase 22.7.11.220.504
3qzfX66Cyclin-dependent kinase 22.7.11.220.503
3r6xX84Cyclin-dependent kinase 22.7.11.220.503
3roy22ZCyclin-dependent kinase 22.7.11.220.503
2b55D31Cyclin-dependent kinase 22.7.11.220.501
2vtsLZCCyclin-dependent kinase 22.7.11.220.501
3sw418KCyclin-dependent kinase 22.7.11.220.500
1dm2HMDCyclin-dependent kinase 22.7.11.220.498
1ykr628Cyclin-dependent kinase 22.7.11.220.498
3r8lZ30Cyclin-dependent kinase 22.7.11.220.498
3lfnA27Cyclin-dependent kinase 22.7.11.220.497
4fkw62KCyclin-dependent kinase 22.7.11.220.497
1ke6LS2Cyclin-dependent kinase 22.7.11.220.496
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.496
2r3p3SCCyclin-dependent kinase 22.7.11.220.495
3ezrEZRCyclin-dependent kinase 22.7.11.220.495
4lyn1YGCyclin-dependent kinase 22.7.11.220.495
2bheBRYCyclin-dependent kinase 22.7.11.220.494
3qruX19Cyclin-dependent kinase 22.7.11.220.494
4ek816KCyclin-dependent kinase 22.7.11.220.493
1ke5LS1Cyclin-dependent kinase 22.7.11.220.492
2vttLZDCyclin-dependent kinase 22.7.11.220.492
2fvdLIACyclin-dependent kinase 22.7.11.220.491
2uznC96Cyclin-dependent kinase 22.7.11.220.491
3qtrX36Cyclin-dependent kinase 22.7.11.220.491
3r1yX76Cyclin-dependent kinase 22.7.11.220.491
3sw719KCyclin-dependent kinase 22.7.11.220.491
1pyePM1Cyclin-dependent kinase 22.7.11.220.490
2r3iSCFCyclin-dependent kinase 22.7.11.220.490
3r7vZ02Cyclin-dependent kinase 22.7.11.220.490
1di8DTQCyclin-dependent kinase 22.7.11.220.489
3qu0X40Cyclin-dependent kinase 22.7.11.220.489
4fki09KCyclin-dependent kinase 22.7.11.220.489
3qwjX6ACyclin-dependent kinase 22.7.11.220.488
1w8cN69Cyclin-dependent kinase 22.7.11.220.487
2r3mSCXCyclin-dependent kinase 22.7.11.220.487
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.487
2vu3LZECyclin-dependent kinase 22.7.11.220.487
3qtqX35Cyclin-dependent kinase 22.7.11.220.487
1ke8LS4Cyclin-dependent kinase 22.7.11.220.485
3rkb12ZCyclin-dependent kinase 22.7.11.220.485
3lfsA07Cyclin-dependent kinase 22.7.11.220.484
1pxpCK8Cyclin-dependent kinase 22.7.11.220.483
2wpa889Cyclin-dependent kinase 22.7.11.220.483
3s0o50ZCyclin-dependent kinase 22.7.11.220.483
3unk0BYCyclin-dependent kinase 22.7.11.220.483
1h0w207Cyclin-dependent kinase 22.7.11.220.482
4fkv61KCyclin-dependent kinase 22.7.11.220.482
1pxlCK4Cyclin-dependent kinase 22.7.11.220.480
3ig7EFPCyclin-dependent kinase 22.7.11.220.479
4nj32KDCyclin-dependent kinase 22.7.11.220.479
1pxkCK3Cyclin-dependent kinase 22.7.11.220.478
2j9mPY8Cyclin-dependent kinase 22.7.11.220.478
2wxvWXVCyclin-dependent kinase 22.7.11.220.477
3r7iX9ICyclin-dependent kinase 22.7.11.220.476
1h1r6CPCyclin-dependent kinase 22.7.11.220.475
3pj8404Cyclin-dependent kinase 22.7.11.220.475
4ii5ADPCyclin-dependent kinase 22.7.11.220.475
1urwI1PCyclin-dependent kinase 22.7.11.220.474
2b52D42Cyclin-dependent kinase 22.7.11.220.474
2uzdC85Cyclin-dependent kinase 22.7.11.220.474
3rpo24ZCyclin-dependent kinase 22.7.11.220.474
3rzb02ZCyclin-dependent kinase 22.7.11.220.474
3py0SU9Cyclin-dependent kinase 22.7.11.220.473
3wblPDYCyclin-dependent kinase 22.7.11.220.473
1vyw292Cyclin-dependent kinase 22.7.11.220.472
2r3jSCJCyclin-dependent kinase 22.7.11.220.472
3rm618ZCyclin-dependent kinase 22.7.11.220.472
4acm7YGCyclin-dependent kinase 22.7.11.220.472
1r78FMDCyclin-dependent kinase 22.7.11.220.471
3r1sX73Cyclin-dependent kinase 22.7.11.220.471
3qzhX69Cyclin-dependent kinase 22.7.11.220.470
3lfqA28Cyclin-dependent kinase 22.7.11.220.468
4fkj11KCyclin-dependent kinase 22.7.11.220.468
1vyzN5BCyclin-dependent kinase 22.7.11.220.467
3r28XA0Cyclin-dependent kinase 22.7.11.220.467
1h1s4SPCyclin-dependent kinase 22.7.11.220.466
4eon1ROCyclin-dependent kinase 22.7.11.220.464
1oguST8Cyclin-dependent kinase 22.7.11.220.463
2a0cCK9Cyclin-dependent kinase 22.7.11.220.463
3qqhX0ACyclin-dependent kinase 22.7.11.220.463
3rahO1ZCyclin-dependent kinase 22.7.11.220.463
4fks46KCyclin-dependent kinase 22.7.11.220.463
4qmpDKISerine/threonine-protein kinase 242.7.11.10.463
2duv371Cyclin-dependent kinase 22.7.11.220.462
2r3r6SCCyclin-dependent kinase 22.7.11.220.462
1gii1PUCyclin-dependent kinase 22.7.11.220.461
2wihP48Cyclin-dependent kinase 22.7.11.220.461
1e1xNW1Cyclin-dependent kinase 22.7.11.220.459
1fvt106Cyclin-dependent kinase 22.7.11.220.459
1pkdUCNCyclin-dependent kinase 22.7.11.220.459
2r64740Cyclin-dependent kinase 22.7.11.220.458
2uzbC75Cyclin-dependent kinase 22.7.11.220.458
3ddqRRCCyclin-dependent kinase 22.7.11.220.458
2cchATPCyclin-dependent kinase 22.7.11.220.456
1oiyN41Cyclin-dependent kinase 22.7.11.220.455
2r3o2SCCyclin-dependent kinase 22.7.11.220.455
4bcmT7ZCyclin-dependent kinase 22.7.11.220.455
1finATPCyclin-dependent kinase 22.7.11.220.454
1oirHDYCyclin-dependent kinase 22.7.11.220.454
3r7eX88Cyclin-dependent kinase 22.7.11.220.454
4eor4SPCyclin-dependent kinase 22.7.11.220.454
5aniES4Cyclin-dependent kinase 22.7.11.220.452
2c6mDT5Cyclin-dependent kinase 22.7.11.220.451
3unj0BXCyclin-dependent kinase 22.7.11.220.451
1b39ATPCyclin-dependent kinase 22.7.11.220.450
2iw94SPCyclin-dependent kinase 22.7.11.220.450
3qqlX03Cyclin-dependent kinase 22.7.11.220.450
3r8pZ46Cyclin-dependent kinase 22.7.11.220.450
4aua4AUCyclin-dependent kinase 62.7.11.220.450
3r8zZ63Cyclin-dependent kinase 22.7.11.220.449
3uli1N3Cyclin-dependent kinase 22.7.11.220.449
3sheI85MAP kinase-activated protein kinase 32.7.11.10.448
2vtqLZACyclin-dependent kinase 22.7.11.220.447
3bhtMFRCyclin-dependent kinase 22.7.11.220.447
3tnwF18Cyclin-dependent kinase 22.7.11.220.447
1aq1STUCyclin-dependent kinase 22.7.11.220.446
3ql8X01Cyclin-dependent kinase 22.7.11.220.446
4fklCK2Cyclin-dependent kinase 22.7.11.220.446
1e9hINRCyclin-dependent kinase 22.7.11.220.445
3my5RFZCyclin-dependent kinase 22.7.11.220.445
3qx2X63Cyclin-dependent kinase 22.7.11.220.445
4bcpT3CCyclin-dependent kinase 22.7.11.220.445
1ke7LS3Cyclin-dependent kinase 22.7.11.220.443
3be9P04Casein kinase II subunit alpha2.7.11.10.442
4eok4SPCyclin-dependent kinase 22.7.11.220.442
2c4g514Cyclin-dependent kinase 22.7.11.220.440
3axwTIDCasein kinase II subunit alpha2.7.11.10.440
3r9oZ71Cyclin-dependent kinase 22.7.11.220.440