Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
1ofv | FMN | Flavodoxin |
PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
---|---|---|---|---|---|
1ofv | FMN | Flavodoxin | / | 1.000 | |
1czn | FMN | Flavodoxin | / | 0.872 | |
1c7f | FMN | Flavodoxin | / | 0.600 | |
1ahn | FMN | Flavodoxin 1 | / | 0.574 | |
2fcr | FMN | Flavodoxin | / | 0.568 | |
4y7c | FMN | NADPH--cytochrome P450 reductase | / | 0.568 | |
1j9g | FMN | Flavodoxin | / | 0.564 | |
3f6r | FMN | Flavodoxin | / | 0.564 | |
3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.561 | |
3hr4 | FMN | Nitric oxide synthase, inducible | 1.14.13.39 | 0.552 | |
1azl | FMN | Flavodoxin | / | 0.541 | |
5xra | FMN | Cannabinoid receptor 1 | / | 0.541 | |
1j9z | FMN | NADPH--cytochrome P450 reductase | / | 0.530 | |
3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.526 | |
1aku | FMN | Flavodoxin | / | 0.525 | |
1wsb | FMN | Flavodoxin | / | 0.524 | |
1fx1 | FMN | Flavodoxin | / | 0.523 | |
2mok | FMN | Flavodoxin 1 | / | 0.523 | |
1akw | FMN | Flavodoxin | / | 0.522 | |
5tgz | FMN | Cannabinoid receptor 1 | / | 0.518 | |
1j8q | FMN | Flavodoxin | / | 0.515 | |
3esy | FMN | Flavodoxin | / | 0.507 | |
2v5v | FMN | Flavodoxin | / | 0.505 | |
4h2d | FMN | NADPH-dependent diflavin oxidoreductase 1 | / | 0.504 | |
3bus | SAH | Demethylrebeccamycin-D-glucose O-methyltransferase | / | 0.502 | |
1afe | ALZ | Prothrombin | 3.4.21.5 | 0.500 | |
3kap | FMN | Flavodoxin | / | 0.495 | |
5fx2 | FMN | Flavodoxin | / | 0.495 | |
5xr8 | FMN | Cannabinoid receptor 1 | / | 0.495 | |
4oxx | FMN | Cindoxin | / | 0.494 | |
2zwa | SAH | tRNA wybutosine-synthesizing protein 4 | 2.1.1.290 | 0.493 | |
1xqp | 8HG | N-glycosylase/DNA lyase | / | 0.492 | |
3esz | FMN | Flavodoxin | / | 0.490 | |
3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.490 | |
4baq | M4Z | Prothrombin | 3.4.21.5 | 0.490 | |
1ppl | 1Z7 | Penicillopepsin-1 | 3.4.23.20 | 0.489 | |
2rc6 | FAD | Ferredoxin--NADP reductase | / | 0.489 | |
1xyy | FMN | Flavodoxin | / | 0.488 | |
2vqb | NAP | Putative flavin-containing monooxygenase | / | 0.488 | |
3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.488 | |
4ozt | P1A | Ecdysone receptor, putative | / | 0.488 | |
1e64 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.486 | |
1k21 | IGN | Prothrombin | 3.4.21.5 | 0.486 | |
3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.486 | |
4fx2 | FMN | Flavodoxin | / | 0.486 | |
3qto | 10P | Prothrombin | 3.4.21.5 | 0.484 | |
4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
2clm | F6F | Tryptophan synthase alpha chain | / | 0.481 | |
2r2m | I50 | Prothrombin | 3.4.21.5 | 0.481 | |
3ex8 | AIF | Riboflavin biosynthesis protein RibD | 1.1.1.193 | 0.480 | |
1fue | FMN | Flavodoxin | / | 0.479 | |
1kru | IPT | Galactoside O-acetyltransferase | 2.3.1.18 | 0.479 | |
2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.478 | |
3eku | CY9 | Actin-5C | / | 0.478 | |
3kaq | FMN | Flavodoxin | / | 0.478 | |
1vzq | SHY | Prothrombin | 3.4.21.5 | 0.477 | |
1yob | FMN | Flavodoxin 2 | / | 0.477 | |
2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.477 | |
3p17 | 99P | Prothrombin | 3.4.21.5 | 0.477 | |
4uaj | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.477 | |
1bu5 | RBF | Flavodoxin | / | 0.476 | |
2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.476 | |
3qtv | 06P | Prothrombin | 3.4.21.5 | 0.476 | |
3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
4c43 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.475 | |
1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.474 | |
3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.474 | |
4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
4mub | OAQ | Sulfotransferase oxamniquine resistance protein | / | 0.474 | |
2iku | LIY | Renin | 3.4.23.15 | 0.473 | |
2pot | GUN | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.473 | |
3mte | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.473 | |
3oqk | S52 | Renin | 3.4.23.15 | 0.473 | |
3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.473 | |
1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.472 | |
2znk | 31U | Prothrombin | 3.4.21.5 | 0.472 | |
4bam | MM9 | Prothrombin | 3.4.21.5 | 0.472 | |
1d9i | 00P | Prothrombin | 3.4.21.5 | 0.471 | |
1ghv | 120 | Prothrombin | 3.4.21.5 | 0.471 | |
2a4x | BLM | Mitomycin-binding protein | / | 0.471 | |
4ban | M6S | Prothrombin | 3.4.21.5 | 0.471 | |
1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.470 | |
1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.470 | |
1kux | CA3 | Serotonin N-acetyltransferase | / | 0.470 | |
1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.470 | |
1fdr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.469 | |
1nzq | 162 | Prothrombin | 3.4.21.5 | 0.469 | |
1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.469 | |
3c1k | T15 | Prothrombin | 3.4.21.5 | 0.469 | |
3rth | RTH | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.469 | |
1gaq | FAD | Ferredoxin | / | 0.468 | |
1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.468 | |
1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.468 | |
2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.468 | |
4bak | M67 | Prothrombin | 3.4.21.5 | 0.468 | |
1bjk | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.467 | |
1owp | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.467 | |
2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
2pia | FMN | Phthalate dioxygenase reductase | / | 0.467 | |
2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.467 | |
3qfs | FAD | NADPH--cytochrome P450 reductase | / | 0.467 | |
1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.466 | |
3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.466 | |
3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
3of3 | DIH | Purine nucleoside phosphorylase DeoD-type 1 | / | 0.466 | |
4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.466 | |
4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.466 | |
1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.465 | |
2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.465 | |
3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.465 | |
1bxq | PP8 | Penicillopepsin-1 | 3.4.23.20 | 0.464 | |
1d3d | BZT | Prothrombin | 3.4.21.5 | 0.464 | |
1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.464 | |
2zfq | 45U | Prothrombin | 3.4.21.5 | 0.464 | |
3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.464 | |
3l7g | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.464 | |
4ug5 | H4B | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.464 | |
1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.463 | |
1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
1qvu | PRL | HTH-type transcriptional regulator QacR | / | 0.463 | |
2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.463 | |
2cle | F6F | Tryptophan synthase alpha chain | / | 0.463 | |
2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.463 | |
2r8p | T6F | Transketolase 1 | / | 0.463 | |
4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.463 | |
1jwt | BLI | Prothrombin | 3.4.21.5 | 0.462 | |
1pg0 | MOD | Methionine--tRNA ligase | 6.1.1.10 | 0.462 | |
1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.462 | |
1w29 | TS0 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.462 | |
2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.462 | |
2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
4utl | FNR | Xenobiotic reductase | / | 0.462 | |
2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
2zg0 | 50U | Prothrombin | 3.4.21.5 | 0.461 | |
3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.461 | |
3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.461 | |
3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.461 | |
4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.461 | |
4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.461 | |
1f3e | DPZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.460 | |
1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.460 | |
2v00 | V15 | Endothiapepsin | 3.4.23.22 | 0.460 | |
3b4p | 3B4 | Phenazine biosynthesis protein A/B | / | 0.460 | |
3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.460 | |
4isu | IKM | Glutamate receptor 2 | / | 0.460 | |
4ivr | N50 | Thymidine kinase | / | 0.460 | |
4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
2cv1 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.459 | |
3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.459 | |
3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.459 | |
3vyd | VYD | Renin | 3.4.23.15 | 0.459 | |
4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.459 | |
1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.458 | |
1pxg | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.458 | |
1wop | FFO | Aminomethyltransferase | / | 0.458 | |
2bxt | C2D | Prothrombin | 3.4.21.5 | 0.458 | |
2web | PP4 | Penicillopepsin-1 | 3.4.23.20 | 0.458 | |
2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
3d91 | REM | Renin | 3.4.23.15 | 0.458 | |
3klb | FMN | Uncharacterized protein | / | 0.458 | |
3udk | 095 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
4g1f | 0WG | Dipeptidyl peptidase 4 | / | 0.458 | |
3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.458 | |
1fw0 | KAI | Glutamate receptor 2 | / | 0.457 | |
1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.457 | |
2g1o | 2IG | Renin | 3.4.23.15 | 0.457 | |
3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.457 | |
1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.456 | |
1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.456 | |
1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
2qmy | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.456 | |
2qmz | LDP | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.456 | |
2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.456 | |
2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
3ndj | JHZ | Methyltransferase | / | 0.456 | |
3t6i | NC8 | Endothiapepsin | 3.4.23.22 | 0.456 | |
3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.456 | |
5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.456 | |
1fvp | FMA | Non-fluorescent flavoprotein | / | 0.455 | |
1sm4 | FAD | Ferredoxin--NADP reductase | / | 0.455 | |
1xyv | FMN | Flavodoxin | / | 0.455 | |
2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
2vr0 | HQO | Cytochrome c-type protein | / | 0.455 | |
2wea | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.455 | |
2zdv | 37U | Prothrombin | 3.4.21.5 | 0.455 | |
3biu | 10U | Prothrombin | 3.4.21.5 | 0.455 | |
3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
3oab | DST | Geranyl diphosphate synthase large subunit | / | 0.455 | |
3wqt | ANP | Cell division protein FtsA | / | 0.455 | |
4bao | MVF | Prothrombin | 3.4.21.5 | 0.455 | |
5icf | SAH | (S)-norcoclaurine 6-O-methyltransferase | / | 0.455 | |
7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.455 | |
1lgt | BP3 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.454 | |
1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.454 | |
2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.454 | |
2g21 | L1B | Renin | 3.4.23.15 | 0.454 | |
2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.454 | |
2v16 | C47 | Renin | 3.4.23.15 | 0.454 | |
3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.454 | |
3o6o | 94M | Heat shock protein 83 | / | 0.454 | |
3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.454 | |
3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.454 | |
4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.454 | |
4du6 | GTP | GTP cyclohydrolase 1 | / | 0.454 | |
4iil | RBF | Membrane lipoprotein TpN38(b) | / | 0.454 | |
4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.454 | |
4qoh | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.454 | |
1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.453 | |
1njj | ORX | Ornithine decarboxylase | / | 0.453 | |
1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.453 | |
2g1r | 3IG | Renin | 3.4.23.15 | 0.453 | |
2g24 | 7IG | Renin | 3.4.23.15 | 0.453 | |
2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.453 | |
2v3h | I25 | Prothrombin | 3.4.21.5 | 0.453 | |
2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.453 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.453 | |
5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.453 | |
5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.453 | |
1ib1 | COT | Serotonin N-acetyltransferase | / | 0.452 | |
1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
1n08 | ADP | Riboflavin kinase | 2.7.1.26 | 0.452 | |
1w1v | ALJ | Chitinase | / | 0.452 | |
2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.452 | |
2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.452 | |
2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.452 | |
3ai0 | PNW | Beta-glucosidase | / | 0.452 | |
3n3a | FMN | Protein NrdI | / | 0.452 | |
3r2f | PB0 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
4a6a | TTP | dCTP deaminase | 3.5.4.13 | 0.452 | |
4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.452 | |
4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
1bim | 0QB | Renin | 3.4.23.15 | 0.451 | |
1gvv | 0GM | Endothiapepsin | 3.4.23.22 | 0.451 | |
1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.451 | |
1ppk | IVV | Penicillopepsin-1 | 3.4.23.20 | 0.451 | |
1rne | C60 | Renin | 3.4.23.15 | 0.451 | |
2wky | IBC | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
2x8h | FAD | Thioredoxin glutathione reductase | / | 0.451 | |
2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.451 | |
3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.451 | |
3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.451 | |
3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
3kn0 | 3TO | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
3n39 | FMN | Protein NrdI | / | 0.451 | |
4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.451 | |
4e7r | 0NW | Prothrombin | 3.4.21.5 | 0.451 | |
1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
1od1 | 0QS | Endothiapepsin | 3.4.23.22 | 0.450 | |
1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.450 | |
2gg9 | U16 | Methionine aminopeptidase | / | 0.450 | |
2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.450 | |
2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.450 | |
2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.450 | |
3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.450 | |
3wqu | ATP | Cell division protein FtsA | / | 0.450 | |
4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
4bpr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.450 | |
4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.450 | |
4n9q | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.450 | |
5d4u | SAM | Uncharacterized protein MJ0489 | / | 0.450 | |
4zj8 | SUV | Orexin receptor type 1 | / | 0.450 | |
1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.449 | |
1j8u | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.449 | |
1krv | 147 | Galactoside O-acetyltransferase | 2.3.1.18 | 0.449 | |
1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.449 | |
1w87 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.449 | |
2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
3ix4 | TX1 | Transcriptional activator protein LasR | / | 0.449 | |
3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.449 | |
3rdq | DTB | Streptavidin | / | 0.449 | |
4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.449 | |
4dxj | 0M9 | Farnesyl pyrophosphate synthase | / | 0.449 | |
4fl0 | PLP | Aminotransferase ALD1, chloroplastic | 2.6.1 | 0.449 | |
4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
4y3q | F02 | Endothiapepsin | 3.4.23.22 | 0.449 | |
1k7f | IAV | Tryptophan synthase alpha chain | / | 0.448 | |
1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
1nmq | 160 | Caspase-3 | 3.4.22.56 | 0.448 | |
1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.448 | |
1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.448 | |
2p99 | YE6 | Methionine aminopeptidase | / | 0.448 | |
2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
3h03 | UBP | Glutamate receptor 2 | / | 0.448 | |
3nhf | VVV | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
3t7q | RB4 | Endothiapepsin | 3.4.23.22 | 0.448 | |
3wbb | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.448 | |
4dxl | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.448 | |
4qoe | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.448 | |
1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.447 | |
1e62 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.447 | |
1ix1 | BB2 | Peptide deformylase | / | 0.447 | |
1p4a | PCP | Pur operon repressor | / | 0.447 | |
1pr1 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.447 | |
1x98 | NAP | Aldose reductase | 1.1.1.21 | 0.447 | |
2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.447 | |
2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.447 | |
2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.447 | |
2g1s | 4IG | Renin | 3.4.23.15 | 0.447 | |
2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.447 | |
2zhq | 27U | Prothrombin | 3.4.21.5 | 0.447 | |
3g5m | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
3gwd | FAD | Cyclohexanone monooxygenase | / | 0.447 | |
3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.447 | |
3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.447 | |
3krf | IPE | Geranyl diphosphate synthase large subunit | / | 0.447 | |
3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.447 | |
3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.447 | |
4rel | KMP | Glycosyltransferase | / | 0.447 | |
4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.447 | |
4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.447 | |
4yao | FAD | NADPH--cytochrome P450 reductase | / | 0.447 | |
1k9s | FM2 | Purine nucleoside phosphorylase DeoD-type | / | 0.446 | |
1owo | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.446 | |
1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.446 | |
2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
2jh5 | 895 | Prothrombin | 3.4.21.5 | 0.446 | |
2pks | G44 | Prothrombin | 3.4.21.5 | 0.446 | |
2r6h | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.446 | |
2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.446 | |
2zhw | 12U | Prothrombin | 3.4.21.5 | 0.446 | |
3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.446 | |
3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.446 | |
3ipk | PMS | Surface protein adhesin | / | 0.446 | |
3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.446 | |
4dbw | 511 | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
4e32 | DWN | Methyltransferase | / | 0.446 | |
4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.446 | |
4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.446 | |
4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.446 | |
5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.446 | |
1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.445 | |
2avx | HTF | Regulatory protein SdiA | / | 0.445 | |
2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.445 | |
2iea | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.445 | |
2y88 | 2ER | Phosphoribosyl isomerase A | 5.3.1.16 | 0.445 | |
3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.445 | |
3own | 3OW | Renin | 3.4.23.15 | 0.445 | |
3psy | RB9 | Endothiapepsin | 3.4.23.22 | 0.445 | |
3qwc | 98P | Prothrombin | 3.4.21.5 | 0.445 | |
3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.445 | |
4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.445 | |
4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.445 | |
4ira | FAD | 4-hydroxyphenylacetate 3-monooxygenase | / | 0.445 | |
4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.445 | |
4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.445 | |
3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.445 | |
1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
1lv8 | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
1swt | BTN | Streptavidin | / | 0.444 | |
2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
2bdy | UNB | Prothrombin | 3.4.21.5 | 0.444 | |
2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.444 | |
2oaz | I96 | Methionine aminopeptidase 2 | / | 0.444 | |
2vro | NDP | 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase | / | 0.444 | |
2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.444 | |
2wd8 | VGF | Pteridine reductase | / | 0.444 | |
2xlu | NA7 | Putative flavin-containing monooxygenase | / | 0.444 | |
2zfp | 19U | Prothrombin | 3.4.21.5 | 0.444 | |
3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.444 | |
3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
3jpu | TY4 | Transcriptional activator protein LasR | / | 0.444 | |
3oqf | S51 | Renin | 3.4.23.15 | 0.444 | |
3rim | TPP | Transketolase | 2.2.1.1 | 0.444 | |
4af6 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.444 | |
4j1e | 1HM | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
4l17 | DNQ | Glutamate receptor 2 | / | 0.444 | |
4l7h | 1W1 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
4zvl | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.444 | |
1gaw | FAD | Ferredoxin | / | 0.443 | |
1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
1jtu | LYB | Thymidylate synthase | / | 0.443 | |
1qh0 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.443 | |
1woo | THG | Aminomethyltransferase | / | 0.443 | |
1ycg | FMN | Nitric oxide reductase | 1 | 0.443 | |
2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.443 | |
2g94 | ZPQ | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.443 | |
2jji | 0QS | Endothiapepsin | 3.4.23.22 | 0.443 | |
2pbz | ATP | Uncharacterized protein | / | 0.443 | |
2rc5 | FAD | Ferredoxin--NADP reductase | / | 0.443 | |
2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.443 | |
2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
2zr9 | DTP | Protein RecA | / | 0.443 | |
3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.443 | |
3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.443 | |
3p2k | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.443 | |
3qbw | ADP | Anhydro-N-acetylmuramic acid kinase | / | 0.443 | |
3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.443 | |
3qvi | K95 | HAP protein | / | 0.443 | |
3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
4es5 | MGT | Polymerase basic protein 2 | / | 0.443 | |
4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.443 | |
4iei | ADP | Gene 2 protein | / | 0.443 | |
4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.443 | |
4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.443 | |
5agy | GTB | Tau class glutathione S-transferase | / | 0.443 | |
5ds3 | 09L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.443 | |
1amo | FAD | NADPH--cytochrome P450 reductase | / | 0.442 | |
1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.442 | |
1bil | 0IU | Renin | 3.4.23.15 | 0.442 | |
1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.442 | |
1uma | IN2 | Prothrombin | 3.4.21.5 | 0.442 | |
1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
1x2e | ATX | Proline iminopeptidase | 3.4.11.5 | 0.442 | |
1zgv | 501 | Prothrombin | 3.4.21.5 | 0.442 | |
2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.442 | |
2j0s | ANP | Eukaryotic initiation factor 4A-III | 3.6.4.13 | 0.442 | |
2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.442 | |
2vt4 | P32 | Beta-1 adrenergic receptor | / | 0.442 | |
3anl | SYC | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.442 | |
3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.442 | |
3vsx | R32 | Renin | 3.4.23.15 | 0.442 | |
3vyf | VYF | Renin | 3.4.23.15 | 0.442 | |
3w3z | GTP | GTP-binding nuclear protein Ran | / | 0.442 | |
3ziu | LSS | Leucyl-tRNA synthetase | / | 0.442 | |
4azm | T4B | Fatty acid-binding protein, epidermal | / | 0.442 | |
4bue | JQF | Tankyrase-2 | 2.4.2.30 | 0.442 | |
4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
1aqv | 0HG | Glutathione S-transferase P | 2.5.1.18 | 0.441 | |
1db4 | 8IN | Phospholipase A2, membrane associated | / | 0.441 | |
1eir | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.441 | |
1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.441 | |
1ja1 | FAD | NADPH--cytochrome P450 reductase | / | 0.441 | |
1ogi | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.441 | |
1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.441 | |
1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.441 | |
1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.441 | |
1zx1 | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.441 | |
2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.441 | |
2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.441 | |
3b9l | AZZ | Serum albumin | / | 0.441 | |
3gu3 | SAH | Methyltransferase | / | 0.441 | |
3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.441 | |
3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
3u8n | 09S | Acetylcholine-binding protein | / | 0.441 | |
3w5u | FAD | Ferredoxin | / | 0.441 | |
4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.441 | |
4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.441 | |
4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.441 | |
4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.441 | |
4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.441 | |
1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.440 | |
1gvt | 2ZS | Endothiapepsin | 3.4.23.22 | 0.440 | |
1ihi | IU5 | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
1mue | CDD | Prothrombin | 3.4.21.5 | 0.440 | |
1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.440 | |
1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.440 | |
1qu2 | MRC | Isoleucine--tRNA ligase | 6.1.1.5 | 0.440 | |
1que | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.440 | |
2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
2g1y | 5IG | Renin | 3.4.23.15 | 0.440 | |
2il2 | LIX | Renin | 3.4.23.15 | 0.440 | |
2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
2onf | COA | Uncharacterized protein | / | 0.440 | |
2wca | NP6 | O-GlcNAcase BT_4395 | / | 0.440 | |
2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
2ycw | CAU | Beta-1 adrenergic receptor | / | 0.440 | |
2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
2zgx | 29U | Prothrombin | 3.4.21.5 | 0.440 | |
3axb | FAD | Putative oxidoreductase | / | 0.440 | |
3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.440 | |
3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.440 | |
3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.440 | |
3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
3uq9 | TBN | Putative adenosine kinase | / | 0.440 | |
3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.440 | |
4bah | MEL | Prothrombin | 3.4.21.5 | 0.440 | |
4dwb | 0M7 | Farnesyl pyrophosphate synthase | / | 0.440 | |
4f1y | CNI | Glutamate receptor 3 | / | 0.440 | |
4jtq | FLP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.440 | |
4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.440 |