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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1o51ADPUPF0166 protein TM_0021

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1o51ADPUPF0166 protein TM_0021/1.000
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.508
1snuSTUTyrosine-protein kinase ITK/TSK2.7.10.20.507
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.504
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.502
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.499
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.499
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.496
2e7zMGDAcetylene hydratase/0.490
2yn8STUEphrin type-B receptor 42.7.10.10.490
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.488
2ag1TPPBenzaldehyde lyase/0.487
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.484
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.484
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.483
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.482
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.482
2ejjSAHDiphthine synthase/0.481
2wipP49Cyclin-dependent kinase 22.7.11.220.481
3zh8C58Protein kinase C iota type2.7.11.130.481
3ox34X4Ribosyldihydronicotinamide dehydrogenase [quinone]/0.480
1o76CAMCamphor 5-monooxygenase1.14.15.10.479
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.478
2yy8SAMtRNA (cytidine(56)-2'-O)-methyltransferase/0.478
4fxy0W2Neurolysin, mitochondrial3.4.24.160.478
2a9y26AAdenosine kinase2.7.1.200.477
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.477
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.477
1pq944BOxysterols receptor LXR-beta/0.476
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.476
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.476
3raiX85Cyclin-dependent kinase 22.7.11.220.475
3zdu38RCyclin-dependent kinase-like 32.7.11.220.475
1drhNAPDihydrofolate reductase1.5.1.30.473
1ezvUQ6Cytochrome b/0.473
1sm2STUTyrosine-protein kinase ITK/TSK2.7.10.20.473
2v59LZKBiotin carboxylase6.3.4.140.473
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.472
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.472
1nhhANPDNA mismatch repair protein MutL/0.471
2hr8SAHDiphthine synthase/0.471
3qtrX36Cyclin-dependent kinase 22.7.11.220.471
1g2vTTPGlucose-1-phosphate thymidylyltransferase/0.470
2hutSAHDiphthine synthase/0.470
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.470
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.470
1nenDNTSuccinate dehydrogenase iron-sulfur subunit1.3.5.10.469
1nenDNTSuccinate dehydrogenase cytochrome b556 subunit/0.469
3cgeCOACoenzyme A disulfide reductase/0.469
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.469
3tnwF18Cyclin-dependent kinase 22.7.11.220.469
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.469
3zewSTUEphrin type-B receptor 42.7.10.10.469
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.469
1f20FADNitric oxide synthase, brain1.14.13.390.468
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.468
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.468
2zbaZBATrichothecene 3-O-acetyltransferase/0.468
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
1bxsNADRetinal dehydrogenase 11.2.1.360.467
2c27ACOMycothiol acetyltransferase2.3.1.1890.467
1pkdUCNCyclin-dependent kinase 22.7.11.220.466
1sbrVIBPutative HMP/thiamine-binding protein YkoF/0.466
3t3iGPWGlycogen phosphorylase, muscle form2.4.1.10.466
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.466
4g95OAGDihydrofolate reductase1.5.1.30.466
4hvh19RTyrosine-protein kinase JAK32.7.10.20.466
4xymCOAAcyl-CoA synthetase (NDP forming)/0.466
1m78NDPDihydrofolate reductase1.5.1.30.465
2a9z26AAdenosine kinase2.7.1.200.465
3megT27Gag-Pol polyprotein2.7.7.490.465
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.465
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.465
4ocvANPAminoglycoside phosphotransferase/0.465
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
1ia4TQ6Dihydrofolate reductase1.5.1.30.464
1q12ATPMaltose/maltodextrin import ATP-binding protein MalK/0.464
1zoyUQ1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial1.3.5.10.464
1zoyUQ1Succinate dehydrogenase cytochrome b560 subunit, mitochondrial/0.464
2e4nSAHDiphthine synthase/0.464
2x4zX4ZSerine/threonine-protein kinase PAK 42.7.11.10.464
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.464
1lwlDSOCamphor 5-monooxygenase1.14.15.10.463
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.463
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.463
2zrfDTPProtein RecA/0.463
3fp0FP015-O-acetyltransferase/0.463
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
3s1dZIRCytokinin dehydrogenase 11.5.99.120.463
4bjx73BBromodomain-containing protein 4/0.463
4cf8V7HIntegrase/0.463
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.463
1q6yCOAFormyl-CoA:oxalate CoA-transferase/0.462
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.462
3cid318Beta-secretase 13.4.23.460.462
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.462
3p0jTYEPutative tyrosyl-tRNA synthetase/0.462
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.462
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.461
2e8hSAHDiphthine synthase/0.461
2i0v6C3Macrophage colony-stimulating factor 1 receptor2.7.10.10.461
2vttLZDCyclin-dependent kinase 22.7.11.220.461
3gb4D3MDdmC/0.461
3maaFKPAdenylate cyclase type 2/0.461
3maaFKPAdenylate cyclase type 5/0.461
4appN53Serine/threonine-protein kinase PAK 42.7.11.10.461
4c61LMMTyrosine-protein kinase JAK2/0.461
4okx198Androgen receptor/0.461
1diuBDMDihydrofolate reductase1.5.1.30.460
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.460
2j09FADDeoxyribodipyrimidine photo-lyase4.1.99.30.460
3ac1KZITyrosine-protein kinase Lck2.7.10.20.460
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.460
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.460
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.460
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.460
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.460
4zp1TPPPyruvate decarboxylase4.1.1.10.460
1mvtDTMDihydrofolate reductase1.5.1.30.459
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2cig1DGDihydrofolate reductase1.5.1.30.459
2x06NADL-sulfolactate dehydrogenase/0.459
3zep1NXTyrosine-protein kinase JAK32.7.10.20.459
4a81DXCMajor pollen allergen Bet v 1-A/0.459
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.459
4wudANPDNA gyrase subunit B/0.459
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.459
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.458
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.458
1zrzBI1Protein kinase C iota type2.7.11.130.458
2e15SAHDiphthine synthase/0.458
2rtoIMIStreptavidin/0.458
3ddpRC8Cyclin-dependent kinase 22.7.11.220.458
3h06VBPGlutamate receptor 2/0.458
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.458
4ogrADNCyclin-dependent kinase 92.7.11.220.458
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.458
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.458
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.457
1qm5PLPMaltodextrin phosphorylase2.4.1.10.457
2ozuACOHistone acetyltransferase KAT6A/0.457
2p5cSAHDiphthine synthase/0.457
2vbdV10Isopenicillin N synthase1.21.3.10.457
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.457
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4fv7E94Mitogen-activated protein kinase 12.7.11.240.457
4j491J1Uncharacterized protein/0.457
4m83ERYOleandomycin glycosyltransferase2.4.10.457
4o701QKBromodomain-containing protein 4/0.457
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.457
1rx8FOLDihydrofolate reductase1.5.1.30.456
1td2PXLPyridoxal kinase PdxY/0.456
2eglSAHDiphthine synthase/0.456
2ghlLIBMitogen-activated protein kinase 14/0.456
2pmnK51Protein kinase 7/0.456
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.456
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.456
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
3fr5I4AFatty acid-binding protein, adipocyte/0.456
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.456
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.456
3pj8404Cyclin-dependent kinase 22.7.11.220.456
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.456
4f6w0SSCyclin-dependent kinase 82.7.11.220.456
1towCRZFatty acid-binding protein, adipocyte/0.455
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.455
2xvq9DSSerum albumin/0.455
3dogNNNCyclin-dependent kinase 22.7.11.220.455
3nr4PYVAbscisic acid receptor PYL2/0.455
3o3jBB4Peptide deformylase 1B, chloroplastic/mitochondrial3.5.1.880.455
3v5j0F2Tyrosine-protein kinase ITK/TSK2.7.10.20.455
4kko1REGag-Pol polyprotein2.7.7.490.455
4q0kGA3Phytohormone-binding protein/0.455
4z24FADPutative GMC-type oxidoreductase R13510.455
1ix1BB2Peptide deformylase/0.454
1s9pDESEstrogen-related receptor gamma/0.454
2hckQUETyrosine-protein kinase HCK2.7.10.20.454
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2w9hTOPDihydrofolate reductase1.5.1.30.454
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3lxpIZANon-receptor tyrosine-protein kinase TYK22.7.10.20.454
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.454
4gk3L87Ephrin type-A receptor 32.7.10.10.454
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.454
4i9h1E4L-lactate dehydrogenase A chain1.1.1.270.454
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.454
4mwhATPCasein kinase II subunit alpha2.7.11.10.454
4z9rFMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.454
1aj22PHDihydropteroate synthase/0.453
1bofGDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.453
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.453
2ab8ACPAdenosine kinase2.7.1.200.453
2dxxSAHDiphthine synthase/0.453
2huqSAHDiphthine synthase/0.453
2v0uFMNNPH1-1/0.453
3cgdCOACoenzyme A disulfide reductase/0.453
3cic316Beta-secretase 13.4.23.460.453
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3m2rCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.453
3m2rCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.453
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.453
4h0vNADIota toxin component Ia/0.453
4lj8ADPChaperone protein ClpB/0.453
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
1g28FMNPHY3/0.452
1gpeFADGlucose oxidase1.1.3.40.452
1h65GDPTranslocase of chloroplast 343.6.50.452
1nooCAHCamphor 5-monooxygenase1.14.15.10.452
1rx8NAPDihydrofolate reductase1.5.1.30.452
1xj7DHTAndrogen receptor/0.452
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.452
2d2iNAPGlyceraldehyde-3-phosphate dehydrogenase/0.452
2dv5SAHDiphthine synthase/0.452
2e08SAHDiphthine synthase/0.452
3imeBZ2Pantothenate synthetase6.3.2.10.452
3jpuTY4Transcriptional activator protein LasR/0.452
3ns2PYVAbscisic acid receptor PYL2/0.452
3orfNADDihydropteridine reductase1.5.1.340.452
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.452
3u8w09JMitogen-activated protein kinase 14/0.452
3v0tATRPerakine reductase1.1.1.3170.452
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.452
4eos1ROCyclin-dependent kinase 22.7.11.220.452
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.452
4la7A1OAbscisic acid receptor PYL2/0.452
4othDRNSerine/threonine-protein kinase N1/0.452
4pb25UDNucleoside permease/0.452
5e8xSTUTGF-beta receptor type-12.7.11.300.452
1oi9N20Cyclin-dependent kinase 22.7.11.220.451
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.451
1upbTPPN(2)-(2-carboxyethyl)arginine synthase/0.451
1uyuCAMCamphor 5-monooxygenase1.14.15.10.451
1xe65FPPlasmepsin-23.4.23.390.451
2bkzSBCCyclin-dependent kinase 22.7.11.220.451
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.451
2ek4SAHDiphthine synthase/0.451
2fbwCBESuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial1.3.5.10.451
2fbwCBESuccinate dehydrogenase cytochrome b, large subunit/0.451
2izuP01Casein kinase I isoform gamma-32.7.11.10.451
2qo9ANPEphrin type-A receptor 32.7.10.10.451
3bnkFMNFlavoredoxin/0.451
3dolGWIPol protein/0.451
3g2hKOTGlycogen phosphorylase, muscle form2.4.1.10.451
3h3sH15Collagen type IV alpha-3-binding protein/0.451
3owj1ELCasein kinase II subunit alpha2.7.11.10.451
3qt62P0Mevalonate diphosphate decarboxylase/0.451
3uxhUXHRibosyldihydronicotinamide dehydrogenase [quinone]/0.451
3wfjNAD2-dehydropantoate 2-reductase/0.451
4a8v2ANMajor pollen allergen Bet v 1-J/0.451
4bgq38RCyclin-dependent kinase-like 52.7.11.220.451
4jhz1KVBeta-glucuronidase3.2.1.310.451
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
1culFOKAdenylate cyclase type 2/0.450
1culFOKAdenylate cyclase type 5/0.450
1h1r6CPCyclin-dependent kinase 22.7.11.220.450
1p4aPCPPur operon repressor/0.450
1qy8RDIEndoplasmin/0.450
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.450
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.450
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.450
2wu5CBESuccinate dehydrogenase iron-sulfur subunit1.3.5.10.450
2wu5CBESuccinate dehydrogenase cytochrome b556 subunit/0.450
2x1nX1NCyclin-dependent kinase 22.7.11.220.450
2y3pSM8DNA gyrase subunit A/0.450
2yegXQGHeat shock protein HSP 90-alpha/0.450
3a20FMNFMN-binding protein/0.450
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
3cbgSAHO-methyltransferase/0.450
3h3qH13Collagen type IV alpha-3-binding protein/0.450
3h3t16HCollagen type IV alpha-3-binding protein/0.450
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.450
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.450
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.450
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.450
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.450
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.450
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.450
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.450
1tqf32PBeta-secretase 13.4.23.460.449
1u2yGOXPancreatic alpha-amylase/0.449
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.449
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.449
2p5yNADUDP-glucose 4-epimerase/0.449
2pcaSAHDiphthine synthase/0.449
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.449
3l7dDK5Glycogen phosphorylase, muscle form2.4.1.10.449
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.449
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.449
4b4vL34Bifunctional protein FolD/0.449
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.449
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.449
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.449
4ubfADPKinesin-like protein KIF2C/0.449
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.448
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.448
1q3sADPThermosome subunit alpha/0.448
1t85CAMCamphor 5-monooxygenase1.14.15.10.448
1vyzN5BCyclin-dependent kinase 22.7.11.220.448
2bunFADAppA protein/0.448
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2dxwSAHDiphthine synthase/0.448
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
2owuSAHDiphthine synthase/0.448
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.448
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.448
3a8wATPProtein kinase C iota type2.7.11.130.448
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.448
3cib314Beta-secretase 13.4.23.460.448
3gamMXXRibosyldihydronicotinamide dehydrogenase [quinone]/0.448
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.448
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.448
4bchT7ZCyclin-dependent kinase 92.7.11.220.448
4ewhT77Activated CDC42 kinase 1/0.448
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
4hsuFADLysine-specific histone demethylase 1B10.448
4ibmIR1Insulin receptor2.7.10.10.448
4oedDHTAndrogen receptor/0.448
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.448
5eccNAPDehydrofolate reductase type I/0.448
1dgmADNAdenosine kinase2.7.1.200.447
1dm2HMDCyclin-dependent kinase 22.7.11.220.447
1gvt2ZSEndothiapepsin3.4.23.220.447
1h1pCMGCyclin-dependent kinase 22.7.11.220.447
1jq3AATPolyamine aminopropyltransferase/0.447
1k8y13PTryptophan synthase alpha chain/0.447
1kp2ATPArgininosuccinate synthase6.3.4.50.447
1l2oADPMyosin heavy chain, striated muscle/0.447
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1t88CAMCamphor 5-monooxygenase1.14.15.10.447
1u0hFOKAdenylate cyclase type 2/0.447
1u0hFOKAdenylate cyclase type 5/0.447
1v0oINRCell division control protein 2 homolog2.7.11.220.447
2e83FMNFMN-binding protein/0.447
2ek3SAHDiphthine synthase/0.447
2erzHFScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2fj1CTCTetracycline repressor protein class D/0.447
2itnANPEpidermal growth factor receptor2.7.10.10.447
2nnqT4BFatty acid-binding protein, adipocyte/0.447
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.447
3amfFMNFMN-binding protein/0.447
3d2mCOAAmino-acid acetyltransferase/0.447
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.447
3nhjA2ZRibosyldihydronicotinamide dehydrogenase [quinone]/0.447
3rm618ZCyclin-dependent kinase 22.7.11.220.447
3rn8RN8Glutamate receptor 2/0.447
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.447
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.447
4lb2DM5Serum albumin/0.447
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.447
4y3zF41Endothiapepsin3.4.23.220.447
1c1c612Gag-Pol polyprotein2.7.7.490.446
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
1r78FMDCyclin-dependent kinase 22.7.11.220.446
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.446
2eldSAHDiphthine synthase/0.446
2huvSAHDiphthine synthase/0.446
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.446
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.446
3a3bRBFLumazine protein/0.446
3elySAHMethyltransferase/0.446
3ii43IIDihydrolipoyl dehydrogenase1.8.1.40.446
3in6FMNUncharacterized protein/0.446
3lkiATPFructokinase/0.446
3qi1C6ABeta-secretase 13.4.23.460.446
3r7eX88Cyclin-dependent kinase 22.7.11.220.446
3tvqDQHMultifunctional cyclase-dehydratase-3-O-methyl transferase TcmN2.1.10.446
3uq9TBNPutative adenosine kinase/0.446
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
4c3yANB3-ketosteroid dehydrogenase/0.446
4cf1IY7Integrase/0.446
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.446
4gpbGFPGlycogen phosphorylase, muscle form2.4.1.10.446
4ivb1J5Tyrosine-protein kinase JAK1/0.446
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.446
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.446
4z17PEPEnolase/0.446
5aluHD2Bifunctional epoxide hydrolase 23.1.3.760.446
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.445
1e9hINRCyclin-dependent kinase 22.7.11.220.445
1flmFMNFMN-binding protein/0.445
1m2rMNYCasein kinase II subunit alpha2.7.11.10.445
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.445
1v59FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.445
2b7aIZATyrosine-protein kinase JAK2/0.445
2ekaSAHDiphthine synthase/0.445
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.445
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.445
2vtqLZACyclin-dependent kinase 22.7.11.220.445
2wd9IBPAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.445
2z0ySAMRibosomal RNA small subunit methyltransferase E/0.445
2zrjAGSProtein RecA/0.445
3b9lAZZSerum albumin/0.445
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3ld6BCDLanosterol 14-alpha demethylase1.14.13.700.445
4c9pCAMCytochrome P450/0.445
4cghLOZIntegrase/0.445
4dc32FAPutative adenosine kinase/0.445
4fvrATPTyrosine-protein kinase JAK2/0.445
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.445
4kne1CYDihydrofolate reductase1.5.1.30.445
4kukRBFPutative blue-light photoreceptor/0.445
4l2yXXKPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.445
4mep24YBromodomain-containing protein 4/0.445
4oztP1AEcdysone receptor, putative/0.445
4wucANPDNA gyrase subunit B/0.445
4yqfGDPSeptin-9/0.445
1df7MTXDihydrofolate reductase1.5.1.30.444
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
1kuvCA5Serotonin N-acetyltransferase/0.444
1phhFADp-hydroxybenzoate hydroxylase/0.444
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.444
2egsSAHDiphthine synthase/0.444
2vd5BI8Myotonin-protein kinase2.7.11.10.444
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.444
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.444
3cnjFADCholesterol oxidase1.1.3.60.444
3dhbC6LN-acyl homoserine lactonase AiiA3.1.1.810.444
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.444
3lpkZ76Beta-secretase 13.4.23.460.444
3qtsX46Cyclin-dependent kinase 22.7.11.220.444
3r4pFU7Heat shock protein HSP 90-alpha/0.444
3r5yF42Uncharacterized protein/0.444
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.444
3zksWZVBeta-secretase 23.4.23.450.444
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.444
4a9iP9IBromodomain-containing protein 2/0.444
4an4DUDPutative glycosyl transferase/0.444
4chqCWUIntegrase/0.444
4cukNAID-lactate dehydrogenase/0.444
4dptAGSMevalonate diphosphate decarboxylase/0.444
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.444
4gk4L90Ephrin type-A receptor 32.7.10.10.444
4ke01R8Beta-secretase 13.4.23.460.444
4ogiR78Bromodomain-containing protein 4/0.444
4r20AERCytochrome P450 family 17 polypeptide 2/0.444
4uugPXGBranched-chain amino acid aminotransferase, putative/0.444
1e1mNAPNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.443
1efpFADElectron transfer flavoprotein subunit alpha/0.443
1ia3TQ5Dihydrofolate reductase1.5.1.30.443
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.443
1rctNOSPurine nucleoside phosphorylase2.4.2.10.443
1vceSAHDiphthine synthase/0.443
1ykgFMNSulfite reductase [NADPH] flavoprotein alpha-component/0.443
2a1oCAMCamphor 5-monooxygenase1.14.15.10.443
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2cchATPCyclin-dependent kinase 22.7.11.220.443
2ek2SAHDiphthine synthase/0.443
2el3SAHDiphthine synthase/0.443
2eleSAHDiphthine synthase/0.443
2iw94SPCyclin-dependent kinase 22.7.11.220.443
2pcgSAHDiphthine synthase/0.443
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.443
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.443
3fz1B98Cyclin-dependent kinase 22.7.11.220.443
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.443
3n0tOPYDipeptidyl peptidase 23.4.14.20.443
3n83ADPAldehyde dehydrogenase, mitochondrial1.2.1.30.443
3sf6FDAGlutaryl-CoA dehydrogenase/0.443
4b4w9L9Bifunctional protein FolD/0.443
4bcoT6QCyclin-dependent kinase 22.7.11.220.443
4c02TAKActivin receptor type-12.7.11.300.443
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.443
4dh60KNBeta-secretase 13.4.23.460.443
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.443
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4fvqATPTyrosine-protein kinase JAK2/0.443
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.443
4l4cCAMCamphor 5-monooxygenase1.14.15.10.443
4l4dCAMCamphor 5-monooxygenase1.14.15.10.443
4mkhAP5Adenylate kinase/0.443
4prxADPDNA gyrase subunit B/0.443
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.443
4zzjCNANAD-dependent protein deacetylase sirtuin-13.5.10.443
1cjvFOKAdenylate cyclase type 2/0.442
1cjvFOKAdenylate cyclase type 5/0.442
1hdrNADDihydropteridine reductase1.5.1.340.442
2bmuU5PUridylate kinase2.7.4.220.442
2cftPLPPyridoxal phosphate phosphatase/0.442
2el0SAHDiphthine synthase/0.442
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.442
2vwqNAPGlucose 1-dehydrogenase/0.442
2xulATPNitrogen regulatory protein P-II/0.442
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.442
3n4kSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.442
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.442
3ql8X01Cyclin-dependent kinase 22.7.11.220.442
3up5NAP2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.442
4a86H35Major pollen allergen Bet v 1-A/0.442
4bb432WEphrin type-B receptor 42.7.10.10.442
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.442
4j0s1H3Bromodomain-containing protein 4/0.442
4j97ACPFibroblast growth factor receptor 2/0.442
4ks7X4ZSerine/threonine-protein kinase PAK 62.7.11.10.442
4rosAPRMalate dehydrogenase/0.442
4xivADPChemotaxis protein CheA2.7.13.30.442
4y4jLNREndothiapepsin3.4.23.220.442
5hs1VORLanosterol 14-alpha demethylase/0.442
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.441
1unlRRCCyclin-dependent-like kinase 52.7.11.10.441
1upaTPPN(2)-(2-carboxyethyl)arginine synthase/0.441
1v35NAIEnoyl-ACP reductase/0.441
2e8rSAHDiphthine synthase/0.441
2i0ePDSProtein kinase C beta type2.7.11.130.441
2owkSAHDiphthine synthase/0.441
2pb6SAHDiphthine synthase/0.441
2w3wVG9Dihydrofolate reductase/0.441
3a9wNADNDP-sugar epimerase/0.441
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
3b2sB2STrichothecene 3-O-acetyltransferase/0.441
3bhtMFRCyclin-dependent kinase 22.7.11.220.441
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3i25MV7Beta-secretase 13.4.23.460.441
3mb601ICasein kinase II subunit alpha2.7.11.10.441
3zs7ATPPyridoxine/pyridoxal/pyridoxamine kinase/0.441
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.441
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4cf7ADPAdenylate kinase/0.441
4eoi1ROCyclin-dependent kinase 22.7.11.220.441
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.441
4erf0R3E3 ubiquitin-protein ligase Mdm26.3.20.441
4f09JAKTyrosine-protein kinase JAK2/0.441
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.441
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.441
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.441
4oavACP2-5A-dependent ribonuclease3.1.260.441
4xcvNDPProbable hydroxyacid dehydrogenase protein/0.441
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.441
4ys22BAUncharacterized protein/0.441
5djtFMNNPH1-2/0.441
5dkkFMNPredicted protein/0.441
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.440
1ikwEFZGag-Pol polyprotein2.7.7.490.440
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.440
1tl7FOKAdenylate cyclase type 2/0.440
1tl7FOKAdenylate cyclase type 5/0.440
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.440
1u5aBIKL-lactate dehydrogenase1.1.1.270.440
1zys199Serine/threonine-protein kinase Chk12.7.11.10.440
2cy2ACOProbable acetyltransferase/0.440
2d4h5GPGuanylate-binding protein 1/0.440
2owvSAHDiphthine synthase/0.440
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.440
2y6o1N1Ephrin type-A receptor 42.7.10.10.440
3aklADPSerine/threonine-protein kinase CtkA2.7.11.10.440
3c15FOKAdenylate cyclase type 2/0.440
3c15FOKAdenylate cyclase type 5/0.440
3eldSFGMethyltransferase/0.440
3fwfCAMCamphor 5-monooxygenase1.14.15.10.440
3gxlQIGTGF-beta receptor type-12.7.11.300.440
3mt817TGlycogen phosphorylase, muscle form2.4.1.10.440
3qqhX0ACyclin-dependent kinase 22.7.11.220.440
3zt3ZT4Integrase/0.440
4bcqTJFCyclin-dependent kinase 22.7.11.220.440
4bw39BMBromodomain-containing protein 4/0.440
4eueNAITrans-2-enoyl-CoA reductase [NADH]/0.440
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.440
4h4qFADBiphenyl dioxygenase ferredoxin reductase subunit/0.440
4i4b1CV3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.440
4qnaX11Serine/threonine-protein kinase 242.7.11.10.440
4uyf73BBromodomain-containing protein 2/0.440
4xhgADPUncharacterized protein/0.440