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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1nqxRLP6,7-dimethyl-8-ribityllumazine synthase2.5.1.78

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1nqxRLP6,7-dimethyl-8-ribityllumazine synthase2.5.1.781.000
1nqw5YL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.574
1rvvINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.513
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.482
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.466