sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1nqu	RDL	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1nqu	RDL	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	1.000
1nqw	5YL	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.597
1nqv	LMZ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.576
1kyx	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.470
2a57	CRM	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.457
1kyy	INI	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.456
4kq6	DLZ	6,7-dimethyl-8-ribityllumazine synthase	/	0.455
2c92	TP6	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.452
2a59	LMZ	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.448
1nqx	RLP	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.447
2c9b	PUG	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.447
1kyv	RBF	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.445