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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1njeDCMThymidylate synthase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1njeDCMThymidylate synthase/1.000
2g89UMPThymidylate synthase/0.541
1tsyUMPThymidylate synthase/0.540
1njdUMPThymidylate synthase/0.533
1jmgUMPThymidylate synthase/0.517
2g86UMPThymidylate synthase/0.517
2g8aUMPThymidylate synthase/0.509
1njbUMPThymidylate synthase/0.501
1vzbUMPThymidylate synthase/0.473
2tdmUMPThymidylate synthase/0.468
1thyUMPThymidylate synthase/0.454
1njaDCMThymidylate synthase/0.452