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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1njaDCMThymidylate synthase

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1njaDCMThymidylate synthase/1.000
1thyUMPThymidylate synthase/0.644
1jmgUMPThymidylate synthase/0.637
1tsyUMPThymidylate synthase/0.611
1njcDCMThymidylate synthase/0.592
1njeDCMThymidylate synthase/0.579
1vzaUMPThymidylate synthase/0.567
1bp6UMPThymidylate synthase/0.552
1vzbUMPThymidylate synthase/0.552
1njdUMPThymidylate synthase/0.548
1tsxUMPThymidylate synthase/0.548
1njbUMPThymidylate synthase/0.542
1jmfUMPThymidylate synthase/0.528
1bp0UMPThymidylate synthase/0.525
2g89UMPThymidylate synthase/0.524
1lcbTMPThymidylate synthase/0.521
1jmiUMPThymidylate synthase/0.518
1lcbDHFThymidylate synthase/0.516
2g86UMPThymidylate synthase/0.512
1jmhUMPThymidylate synthase/0.480
1tsvUMPThymidylate synthase/0.458
1vzdCB3Thymidylate synthase/0.457
1tvvCB3Thymidylate synthase/0.447
2g8aUMPThymidylate synthase/0.441