sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1nhz | 486 | Glucocorticoid receptor |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1nhz | 486 | Glucocorticoid receptor | / | 1.000 | |
| 2ovh | AS0 | Progesterone receptor | / | 0.542 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.507 | |
| 2w8y | 486 | Progesterone receptor | / | 0.481 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.481 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.460 | |
| 3n0t | OPY | Dipeptidyl peptidase 2 | 3.4.14.2 | 0.451 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.451 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.451 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.448 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.447 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.445 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 4jnc | 1LF | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.442 | |
| 3h18 | PMS | Esterase/lipase | / | 0.440 |