sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1ngi	ANP	Heat shock cognate 71 kDa protein

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1ngi	ANP	Heat shock cognate 71 kDa protein	/	1.000
1ngh	ATP	Heat shock cognate 71 kDa protein	/	0.678
1atr	ADP	Heat shock cognate 71 kDa protein	/	0.659
1nge	ATP	Heat shock cognate 71 kDa protein	/	0.638
1ngb	ADP	Heat shock cognate 71 kDa protein	/	0.593
1ngc	ADP	Heat shock cognate 71 kDa protein	/	0.540
3hsc	ADP	Heat shock cognate 71 kDa protein	/	0.513
2qwq	ADP	Heat shock cognate 71 kDa protein	/	0.506
2qwr	ANP	Heat shock cognate 71 kDa protein	/	0.496
3ldl	ATP	78 kDa glucose-regulated protein	/	0.491
1ats	ADP	Heat shock cognate 71 kDa protein	/	0.482
5f2r	ACP	78 kDa glucose-regulated protein	/	0.459
2qwn	ADP	Heat shock cognate 71 kDa protein	/	0.453