sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1n5q | TNC | ActVA 6 protein |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1n5q | TNC | ActVA 6 protein | / | 1.000 | |
| 1n5t | OAL | ActVA 6 protein | / | 0.595 | |
| 1n5s | ADL | ActVA 6 protein | / | 0.572 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.555 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.501 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.493 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.492 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.491 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.490 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.489 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.489 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.489 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.487 | |
| 4cax | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.485 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.482 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.482 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.481 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.480 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.479 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.479 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.479 | |
| 4lt6 | 3AT | Poly(A) polymerase gamma | 2.7.7.19 | 0.479 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.479 | |
| 2ejz | SAH | Diphthine synthase | / | 0.478 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.478 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.478 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.477 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.477 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.477 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.477 | |
| 1osv | CHC | Bile acid receptor | / | 0.476 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.476 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.476 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.476 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.475 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1q19 | SSC | Carbapenam-3-carboxylate synthase | 6.3.3.6 | 0.475 | |
| 1zdw | FLV | Prenyltransferase | / | 0.475 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.475 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.474 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.474 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.474 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.474 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.474 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.473 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.472 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.472 | |
| 2xvv | 9DN | Serum albumin | / | 0.472 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.471 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.471 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.471 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.471 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.470 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.470 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.470 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.469 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.469 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.469 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.468 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.468 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.468 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.468 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.468 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 2bbw | GP5 | Adenylate kinase 4, mitochondrial | / | 0.467 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.467 | |
| 3b9l | AZZ | Serum albumin | / | 0.467 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.467 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.467 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.467 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.467 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.466 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.466 | |
| 2bxq | IMN | Serum albumin | / | 0.466 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.466 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.466 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.466 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.466 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.466 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.465 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.465 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.465 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.465 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.465 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.465 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.465 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.464 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.464 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.464 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.464 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.464 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.463 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.463 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.463 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.463 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.463 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.463 | |
| 4iae | 1DX | Alr2278 protein | / | 0.463 | |
| 5dp2 | NAP | CurF | / | 0.463 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.463 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.463 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.462 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.462 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.462 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.462 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.462 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.462 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.462 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.462 | |
| 4kxn | 6K6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.462 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.462 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.462 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.462 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.462 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.461 | |
| 1e2n | RCA | Thymidine kinase | / | 0.461 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.461 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.461 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.461 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.461 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.461 | |
| 1lqu | NDP | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.460 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.460 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3egv | SAH | Ribosomal protein L11 methyltransferase | 2.1.1 | 0.460 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.460 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.460 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4iah | 1DX | Alr2278 protein | / | 0.460 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.460 | |
| 4l4x | NDP | AmphI | / | 0.460 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.459 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.459 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.459 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.459 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.459 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.459 | |
| 4l8u | 9AZ | Serum albumin | / | 0.459 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.458 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.458 | |
| 2prh | 238 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.458 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.458 | |
| 2xvw | 9NR | Serum albumin | / | 0.458 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.458 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.458 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.458 | |
| 4zas | TYD | CalS13 | / | 0.458 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.457 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.457 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1m52 | P17 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.457 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.457 | |
| 2op1 | 8PC | Enoyl-ACP reductase | / | 0.457 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.457 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.457 | |
| 4agd | B49 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.457 | |
| 4e2b | FMN | Dehydrogenase | / | 0.457 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.457 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.457 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.457 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.456 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.456 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.456 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.456 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.456 | |
| 3gts | D3M | DdmC | / | 0.456 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.456 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.456 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.456 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.456 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.456 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.456 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.455 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.455 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.455 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.455 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.455 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.455 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.455 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.455 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.455 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.454 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.454 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.454 | |
| 1swt | BTN | Streptavidin | / | 0.454 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.454 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.454 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.454 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.454 | |
| 3gob | HXX | DdmC | / | 0.454 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.454 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.454 | |
| 3zsr | O3N | Integrase | / | 0.454 | |
| 4cez | O3N | Integrase | / | 0.454 | |
| 4cf8 | V7H | Integrase | / | 0.454 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.453 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.453 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.453 | |
| 1pox | FAD | Pyruvate oxidase | 1.2.3.3 | 0.453 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.453 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.453 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.453 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.453 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.453 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.453 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.453 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.453 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 1bmd | NAD | Malate dehydrogenase | / | 0.452 | |
| 1eio | GCH | Gastrotropin | / | 0.452 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.452 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.452 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.452 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.452 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.452 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.452 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.452 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.452 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.452 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.451 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1q6y | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.451 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.451 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.451 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.451 | |
| 2bxm | IMN | Serum albumin | / | 0.451 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.451 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.451 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.451 | |
| 2y3r | TRK | TamL | / | 0.451 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.451 | |
| 3pqf | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.451 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.451 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.451 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.451 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4jln | 18V | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 5dbf | NDP | Iridoid synthase | 1.3.1.99 | 0.451 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.450 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.450 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.450 | |
| 1yw1 | FMN | Putative monooxygenase MoxC | 1.14 | 0.450 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3eku | CY9 | Actin-5C | / | 0.450 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.450 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.450 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.450 | |
| 3myk | BIT | Myosin-2 heavy chain | / | 0.450 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.450 | |
| 3p0h | FSE | Putative tyrosyl-tRNA synthetase | / | 0.450 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 4ceq | QCH | Integrase | / | 0.450 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.450 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.450 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.450 | |
| 4wuc | ANP | DNA gyrase subunit B | / | 0.450 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.450 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.450 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.449 | |
| 1mei | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.449 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.449 | |
| 1r2j | FAD | FkbI | / | 0.449 | |
| 1sny | NAP | LD36273p | / | 0.449 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.449 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.449 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.449 | |
| 2hg1 | N5O | Endoplasmin | / | 0.449 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.449 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.449 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.449 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.449 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.449 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.449 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.449 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.449 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.449 | |
| 3koz | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.449 | |
| 3oia | A31 | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 3vf8 | 0JE | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.449 | |
| 4cf1 | IY7 | Integrase | / | 0.449 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.449 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.449 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.449 | |
| 4lb2 | DM5 | Serum albumin | / | 0.449 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.449 | |
| 4xcv | NDP | Probable hydroxyacid dehydrogenase protein | / | 0.449 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.448 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.448 | |
| 1sep | BIO | Sepiapterin reductase | 1.1.1.153 | 0.448 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.448 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.448 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.448 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.448 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.448 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.448 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.448 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.448 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.448 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.448 | |
| 4dxd | 9PC | Cell division protein FtsZ | / | 0.448 | |
| 4kwh | NAP | Reductase homolog | / | 0.448 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.448 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.448 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.447 | |
| 1pxx | DIF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.447 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.447 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.447 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.447 | |
| 2y05 | RAL | Prostaglandin reductase 1 | / | 0.447 | |
| 3a14 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.447 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.447 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.447 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.447 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.447 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.447 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.446 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.446 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.446 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.446 | |
| 1piw | NAP | NADP-dependent alcohol dehydrogenase 6 | 1.1.1.2 | 0.446 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.446 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.446 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.446 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.446 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.446 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.446 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.446 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.446 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.446 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.446 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.446 | |
| 4fox | UMP | Thymidylate synthase ThyA | / | 0.446 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.446 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.446 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.446 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.446 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.446 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.446 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.446 | |
| 1f3e | DPZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.445 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.445 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.445 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.445 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.445 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.445 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.445 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.445 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.445 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.445 | |
| 2rr1 | W8R | Genome polyprotein | / | 0.445 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.445 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.445 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.445 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.445 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.445 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.445 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.445 | |
| 3ujl | A8S | Abscisic acid receptor PYL2 | / | 0.445 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.445 | |
| 4ew3 | DXZ | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.445 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.445 | |
| 4ih7 | 1ER | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.445 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.445 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.445 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.445 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.445 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.444 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.444 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1prc | UQ1 | Reaction center protein L chain | / | 0.444 | |
| 1td2 | PXL | Pyridoxal kinase PdxY | / | 0.444 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.444 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.444 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.444 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.444 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.444 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.444 | |
| 2qen | ADP | Walker-Type ATPase | / | 0.444 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.444 | |
| 3gb4 | D3M | DdmC | / | 0.444 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.444 | |
| 3pxy | JWS | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.444 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.444 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.444 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 4h03 | LAR | Actin, alpha skeletal muscle | / | 0.444 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.444 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.444 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.444 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.444 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.444 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.444 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.443 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.443 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.443 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.443 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.443 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3cjf | SAV | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.443 | |
| 3eks | CY9 | Actin-5C | / | 0.443 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.443 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.443 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.443 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.443 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4ck2 | NVU | Integrase | / | 0.443 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.443 | |
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 0.443 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.443 | |
| 4hxy | NDP | Plm1 | / | 0.443 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.443 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.443 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.443 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.443 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.443 | |
| 1cq8 | PY6 | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.442 | |
| 1gnw | GTX | Glutathione S-transferase F2 | 2.5.1.18 | 0.442 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.442 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 2c27 | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.442 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.442 | |
| 2ol4 | JPN | Enoyl-ACP reductase | / | 0.442 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.442 | |
| 2ww4 | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.442 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3ix3 | OHN | Transcriptional activator protein LasR | / | 0.442 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.442 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 3o15 | 3NM | Thiamine-phosphate synthase | / | 0.442 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.442 | |
| 3w4y | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.442 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.442 | |
| 4cfl | 8DQ | Bromodomain-containing protein 4 | / | 0.442 | |
| 4ckc | SAH | mRNA-capping enzyme catalytic subunit | 2.1.1.56 | 0.442 | |
| 4k5s | PM0 | Oxygenase | / | 0.442 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.442 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.442 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1a4l | DCF | Adenosine deaminase | 3.5.4.4 | 0.441 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.441 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.441 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.441 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.441 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.441 | |
| 1cx2 | S58 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.441 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.441 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.441 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.441 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.441 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.441 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.441 | |
| 2ohh | FMN | Type A flavoprotein FprA | 1 | 0.441 | |
| 2rg5 | 279 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.441 | |
| 2vos | ADP | Folylpolyglutamate synthase | / | 0.441 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.441 | |
| 2ywv | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | / | 0.441 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.441 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 3ojx | NAP | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 3ppo | DCK | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.441 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.441 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.441 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.441 | |
| 4dzz | ADP | Plasmid partitioning protein ParF | / | 0.441 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.441 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4hyh | 1AM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.441 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.441 | |
| 5agk | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.441 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.441 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.441 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.440 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.440 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.440 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.440 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.440 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.440 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.440 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.440 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.440 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.440 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.440 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.440 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.440 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.440 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.440 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.440 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.440 |