sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1mxt	FAE	Cholesterol oxidase	1.1.3.6

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1mxt	FAE	Cholesterol oxidase	1.1.3.6	1.000
1n4u	FAE	Cholesterol oxidase	1.1.3.6	0.845
4u2l	SFD	Cholesterol oxidase	1.1.3.6	0.779
4u2s	FDA	Cholesterol oxidase	1.1.3.6	0.695
1ijh	FAD	Cholesterol oxidase	1.1.3.6	0.645
1cc2	FAD	Cholesterol oxidase	1.1.3.6	0.638
4rek	FAD	Cholesterol oxidase	1.1.3.6	0.615
1n4v	FAD	Cholesterol oxidase	1.1.3.6	0.607
1b4v	FAD	Cholesterol oxidase	1.1.3.6	0.575
1b8s	FAD	Cholesterol oxidase	1.1.3.6	0.572
3gyi	FAD	Cholesterol oxidase	1.1.3.6	0.552
1cbo	FAD	Cholesterol oxidase	1.1.3.6	0.520
3cnj	FAD	Cholesterol oxidase	1.1.3.6	0.494
3cox	FAD	Cholesterol oxidase	1.1.3.6	0.483