sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1mc0 | PCG | cGMP-dependent 3',5'-cyclic phosphodiesterase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1mc0 | PCG | cGMP-dependent 3',5'-cyclic phosphodiesterase | / | 1.000 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.477 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.464 | |
| 3qbw | ADP | Anhydro-N-acetylmuramic acid kinase | / | 0.456 | |
| 3qak | UKA | Adenosine receptor A2a | / | 0.454 | |
| 2f6r | ACO | Bifunctional coenzyme A synthase | / | 0.452 | |
| 3e9s | TTT | Replicase polyprotein 1ab | 3.4.22 | 0.448 | |
| 1dnp | MHF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.445 | |
| 3ix8 | TX3 | Transcriptional activator protein LasR | / | 0.443 |