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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.8

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.81.000
4pnmNU1Tankyrase-22.4.2.300.524
2wo7ASVIsopenicillin N synthase1.21.3.10.521
3q0vLL4HTH-type transcriptional regulator EthR/0.519
3tp0FO5HTH-type transcriptional regulator EthR/0.519
2vcmM11Isopenicillin N synthase1.21.3.10.518
2y6fM9FIsopenicillin N synthase1.21.3.10.515
3emlZMAAdenosine receptor A2a/0.514
3o8gO8GHTH-type transcriptional regulator EthR/0.513
1upw444Oxysterols receptor LXR-beta/0.511
1hb1OCVIsopenicillin N synthase1.21.3.10.510
2vbpVB1Isopenicillin N synthase1.21.3.10.510
2y60M8FIsopenicillin N synthase1.21.3.10.509
1w06W05Isopenicillin N synthase1.21.3.10.508
2jb4A14Isopenicillin N synthase1.21.3.10.508
3o8hO8HHTH-type transcriptional regulator EthR/0.508
3zoiM2WIsopenicillin N synthase1.21.3.10.508
1blzACVIsopenicillin N synthase1.21.3.10.507
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.507
1obnASVIsopenicillin N synthase1.21.3.10.507
1qjfACSIsopenicillin N synthase1.21.3.10.507
3zkyWT4Isopenicillin N synthase1.21.3.10.506
2bu9HFVIsopenicillin N synthase1.21.3.10.504
3up0D7SaceDAF-12/0.501
4eiyZMAAdenosine receptor A2a/0.501
4fhi0S4Vitamin D3 receptor A/0.501
1ie8KH1Vitamin D3 receptor/0.499
1s0zEB1Vitamin D3 receptor/0.499
1sreHABStreptavidin/0.499
2fhnBNIAvidin-related protein 4/5/0.499
3hz5Z64Heat shock protein HSP 90-alpha/0.499
3zkuHCVIsopenicillin N synthase1.21.3.10.499
4twnB96Ephrin type-A receptor 32.7.10.10.499
4jlj1NMDeoxycytidine kinase2.7.1.740.498
1rkhVD2Vitamin D3 receptor/0.497
1s19MC9Vitamin D3 receptor/0.497
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.497
1bk0ACVIsopenicillin N synthase1.21.3.10.496
1p8dCO1Oxysterols receptor LXR-beta/0.496
1pq6965Oxysterols receptor LXR-beta/0.496
4bb3KKAIsopenicillin N synthase1.21.3.10.496
1o6qR17Squalene--hopene cyclase4.2.1.1290.495
2harOCCVitamin D3 receptor/0.495
3w0yDS4Vitamin D3 receptor/0.495
4g1d0VKVitamin D3 receptor A/0.495
1crbRTLRetinol-binding protein 1/0.494
2hb7O1CVitamin D3 receptor/0.494
4imfSI3N-acetylneuraminate lyase/0.494
2f2sCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.493
2vbdV10Isopenicillin N synthase1.21.3.10.493
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.493
3kpzZNEVitamin D3 receptor/0.493
1qiqACCIsopenicillin N synthase1.21.3.10.492
2hcdBIVVitamin D3 receptor A/0.492
2izkGLLStreptavidin/0.492
3q0uLL3HTH-type transcriptional regulator EthR/0.492
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.492
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.492
3u8dU8DPhospholipase A2, membrane associated/0.491
1oc1ASVIsopenicillin N synthase1.21.3.10.490
1y6qTDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.490
2hbhXE4Vitamin D3 receptor A/0.490
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.490
3csdEMOPutative ketoacyl reductase1.3.10.490
3up3XCAaceDAF-12/0.490
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.490
1stpBTNStreptavidin/0.489
1uykPUXHeat shock protein HSP 90-alpha/0.489
1uzwCDHIsopenicillin N synthase1.21.3.10.489
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.489
2fpcSCGStrictosidine synthase4.3.3.20.489
3w0aDS5Vitamin D3 receptor/0.489
3w5rLOAVitamin D3 receptor/0.489
5iu86DZAdenosine receptor A2a/0.489
1fkwPURAdenosine deaminase3.5.4.40.488
1uy6PU3Heat shock protein HSP 90-alpha/0.488
3vt3VDXVitamin D3 receptor/0.488
4l091URTankyrase-22.4.2.300.488
1hb3SCVIsopenicillin N synthase1.21.3.10.487
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.487
2aa71CAMineralocorticoid receptor/0.487
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.487
2oaxSNLMineralocorticoid receptor/0.487
3nr4PYVAbscisic acid receptor PYL2/0.487
3thrC2FGlycine N-methyltransferase2.1.1.200.486
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.486
4phlPILPhosphodiesterase/0.486
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.486
2hb8MVDVitamin D3 receptor/0.485
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.485
5k2cZMAAdenosine receptor A2a/0.485
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.484
2rtkGLLStreptavidin/0.484
2ydoADNAdenosine receptor A2a/0.484
3wznBTNStreptavidin/0.484
4jqh1MFAlr2278 protein/0.484
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.483
2j7cIDEBeta-glucosidase A3.2.1.210.483
2qdsMCOMetallo-beta-lactamase type 2/0.483
2qhxFE1Pteridine reductase 11.5.1.330.483
3a783EVVitamin D3 receptor/0.483
1ie9VDXVitamin D3 receptor/0.482
1pq944BOxysterols receptor LXR-beta/0.482
2gvcFADThiol-specific monooxygenase1.14.130.482
3g1lRF2HTH-type transcriptional regulator EthR/0.482
4a83DXCMajor pollen allergen Bet v 1-A/0.482
4g8bHL6Alpha/beta hydrolase fold protein/0.482
5k2bZMAAdenosine receptor A2a/0.482
5jtbZMAAdenosine receptor A2a/0.482
1umlFR4Adenosine deaminase3.5.4.40.481
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.481
2kceD16Thymidylate synthase/0.481
3d73NBBPheromone-binding protein ASP1/0.481
3gwfFADCyclohexanone monooxygenase/0.481
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.481
3ntaCOAFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.481
4g1z0VPVitamin D3 receptor A/0.481
4jlk1NODeoxycytidine kinase2.7.1.740.481
4o7nADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.481
1aoeGW3Dihydrofolate reductase1.5.1.30.480
1mk5BTNStreptavidin/0.480
1txiTX5Vitamin D3 receptor/0.480
3vi5M4MHematopoietic prostaglandin D synthase/0.480
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.479
2j9lATPH(+)/Cl(-) exchange transporter 5/0.479
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.479
3i2834NBifunctional epoxide hydrolase 23.3.2.100.479
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.479
3vt5YI2Vitamin D3 receptor/0.479
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.479
4v26TF3[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.479
5g53NECAdenosine receptor A2a/0.479
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.478
2z3uCRRCytochrome P450/0.478
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.478
3djfBC3Purine nucleoside phosphorylase/0.478
3i0pNADMalate dehydrogenase, putative/0.478
3vrvYSDVitamin D3 receptor/0.478
3w0gW07Vitamin D3 receptor/0.478
4bb2STRCorticosteroid-binding globulin/0.478
4cukNAID-lactate dehydrogenase/0.478
4dhyS41Glucokinase2.7.1.20.478
4g210VPVitamin D3 receptor A/0.478
1cjkFOKAdenylate cyclase type 2/0.477
1cjkFOKAdenylate cyclase type 5/0.477
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.477
1wxyFRKAdenosine deaminase3.5.4.40.477
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
2bf7HBIPteridine reductase 11.5.1.330.477
2hamC33Vitamin D3 receptor/0.477
3cgbCOACoenzyme A disulfide reductase/0.477
5dx1SFGHistone-arginine methyltransferase CARM1/0.477
1zw9H64ATP-dependent molecular chaperone HSP82/0.476
3i8aN22Dihydrofolate reductase1.5.1.30.476
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.476
3n0hTOPDihydrofolate reductase1.5.1.30.476
3ntz3TZDihydrofolate reductase1.5.1.30.476
5hbsRTLRetinol-binding protein 1/0.476
1diuBDMDihydrofolate reductase1.5.1.30.475
1fkxPRHAdenosine deaminase3.5.4.40.475
1lcwSHMStreptavidin/0.475
2r0pK2CPutative FAD-monooxygenase/0.475
2yk2YJWHeat shock protein HSP 90-alpha/0.475
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.475
4dw60MNHTH-type transcriptional regulator EthR/0.475
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.475
1f5fDHTSex hormone-binding globulin/0.474
1fdtESTEstradiol 17-beta-dehydrogenase 11.1.1.620.474
2hzqSTRApolipoprotein D/0.474
2iziBTNStreptavidin/0.474
2vrjNCWBeta-glucosidase A3.2.1.210.474
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.474
2yk2YJXHeat shock protein HSP 90-alpha/0.474
3dr1C5DVitamin D3 receptor A/0.474
3vt7VDXVitamin D3 receptor/0.474
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.474
5k2aZMAAdenosine receptor A2a/0.474
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
1rxhBNIStreptavidin/0.473
2amb17HAndrogen receptor/0.473
2x6o2TCTetracycline repressor protein class D/0.473
2ydvNECAdenosine receptor A2a/0.473
2ykjYKJHeat shock protein HSP 90-alpha/0.473
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.473
3sfi3SFHTH-type transcriptional regulator EthR/0.473
3vruYS3Vitamin D3 receptor/0.473
4bquCLRJapanin/0.473
4fhd0TTSpore photoproduct lyase/0.473
4o95245Cytokinin dehydrogenase 4/0.473
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.473
5iubCLRAdenosine receptor A2a/0.473
1d3hA26Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.472
1db1VDXVitamin D3 receptor/0.472
1fmjRTLRetinol dehydratase/0.472
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.472
2hl2SSAThreonine--tRNA ligase6.1.1.30.472
2ij7TPFMycocyclosin synthase1.14.21.90.472
2qpyDHTAndrogen receptor/0.472
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.472
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.472
3vt8YI3Vitamin D3 receptor/0.472
3w0iO11Vitamin D3 receptor/0.472
4gg1TZDBenzoylformate decarboxylase4.1.1.70.472
4ia3BIVVitamin D3 receptor A/0.472
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.472
5bukFADFADH2-dependent halogenase/0.472
5iua6DXAdenosine receptor A2a/0.472
1rk3VDXVitamin D3 receptor/0.471
1rkgVD1Vitamin D3 receptor/0.471
2abi1CAMineralocorticoid receptor/0.471
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.471
2ftoCB3Thymidylate synthase/0.471
2yoj8Y6Genome polyprotein2.7.7.480.471
3biz61EWee1-like protein kinase2.7.10.20.471
3nj0PYVAbscisic acid receptor PYL2/0.471
3pd4A3GThreonine--tRNA ligase6.1.1.30.471
4dneDTBStreptavidin/0.471
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.471
4v2gITCTetracycline repressor protein class D/0.471
1mvtDTMDihydrofolate reductase1.5.1.30.470
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.470
3f0aACOSpermidine N(1)-acetyltransferase/0.470
3ihgVAKAklavinone 12-hydroxylase RdmE/0.470
3vt65YIVitamin D3 receptor/0.470
4bhw01KHistone acetyltransferase p300/0.470
4k7aDHTAndrogen receptor/0.470
3sn6P0GBeta-2 adrenergic receptor/0.470
1h36R88Squalene--hopene cyclase4.2.1.1290.469
1mrqSTRAldo-keto reductase family 1 member C1/0.469
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.469
1xduSFGAclacinomycin 10-hydroxylase RdmB4.1.10.469
2aa2AS4Mineralocorticoid receptor/0.469
2aa6STRMineralocorticoid receptor/0.469
2aclL05Oxysterols receptor LXR-alpha/0.469
2ftoTMPThymidylate synthase/0.469
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.469
3ns2PYVAbscisic acid receptor PYL2/0.469
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.469
4h6rFDAProline dehydrogenase/0.469
4iteTEYVitamin D3 receptor/0.469
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.469
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.469
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.468
1muuGDXGDP-mannose 6-dehydrogenase1.1.1.1320.468
1rjkVDZVitamin D3 receptor/0.468
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.468
1sriDMBStreptavidin/0.468
2bfaCB3Pteridine reductase 11.5.1.330.468
2fwyH64Heat shock protein HSP 90-alpha/0.468
2j5sKTAAlr4455 protein/0.468
3hz142CHeat shock protein HSP 90-alpha/0.468
3nmhPYVAbscisic acid receptor PYL2/0.468
3qm4PN0Cytochrome P450 2D6/0.468
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.468
4jhiEMUNodulin-13/0.468
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.468
1afeALZProthrombin3.4.21.50.467
1uy8PU5Heat shock protein HSP 90-alpha/0.467
2hc4VDXVitamin D3 receptor A/0.467
2o4rVD5Vitamin D3 receptor/0.467
2po7CHDFerrochelatase, mitochondrial4.99.1.10.467
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
3hxeBD8Geranylgeranyl transferase type-2 subunit beta2.5.1.600.467
3w78CBDFMN-dependent NADH-azoreductase/0.467
3zr7OR8Progesterone receptor/0.467
4ddrMMVDihydrofolate reductase1.5.1.30.467
4mubOAQSulfotransferase oxamniquine resistance protein/0.467
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.467
1axwMTXThymidylate synthase/0.466
1kl2FONSerine hydroxymethyltransferase/0.466
1kziTHGThymidylate synthase/0.466
1m78CLZDihydrofolate reductase1.5.1.30.466
1me6IVSPlasmepsin-23.4.23.390.466
1nceCB3Thymidylate synthase/0.466
1ndzFR5Adenosine deaminase3.5.4.40.466
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.466
2aaxPDNMineralocorticoid receptor/0.466
2p5uNADUDP-glucose 4-epimerase/0.466
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.466
3k3kA8SAbscisic acid receptor PYR1/0.466
1wklATPNucleoside diphosphate kinase/0.465
2a19ANPInterferon-induced, double-stranded RNA-activated protein kinase2.7.11.10.465
2bfmTOPPteridine reductase 11.5.1.330.465
2bfpH4BPteridine reductase 11.5.1.330.465
2pioDHTAndrogen receptor/0.465
2tpsTPSThiamine-phosphate synthase/0.465
3frfXCFDihydrofolate reductase1.5.1.30.465
3nmpPYVAbscisic acid receptor PYL2/0.465
3ry2BTNStreptavidin/0.465
3vi7CBDHematopoietic prostaglandin D synthase/0.465
3vrwYS5Vitamin D3 receptor/0.465
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.465
4j6cSTRCytochrome P450 monooxygenase/0.465
4knzCB3Thymidylate synthase/0.465
4x24TDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.465
7catNDPCatalase1.11.1.60.465
1o5rFR9Adenosine deaminase3.5.4.40.464
2flhZEACytokinin-specific binding protein/0.464
3abiNADUncharacterized protein/0.464
3b5iSAHIndole-3-acetate O-methyltransferase 1/0.464
3s41S41Glucokinase2.7.1.20.464
3sf6FDAGlutaryl-CoA dehydrogenase/0.464
3stuDK3Methylketone synthase I/0.464
4cdmFO1Deoxyribodipyrimidine photolyase/0.464
4dvi2IWTankyrase-12.4.2.300.464
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.464
4uofDATNucleoside diphosphate kinase/0.464
5bt42LOBromodomain-containing protein 4/0.464
1d4dFADFumarate reductase flavoprotein subunit1.3.5.40.463
1dtpAPUDiphtheria toxin/0.463
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.463
2o4jVD4Vitamin D3 receptor/0.463
3g5qFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.463
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
3l0lHC3Nuclear receptor ROR-gamma/0.463
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.463
3w5eNVWcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.463
4b4vL34Bifunctional protein FolD/0.463
4er7AW3Histone-lysine N-methyltransferase, H3 lysine-79 specific2.1.1.430.463
4ia1BIVVitamin D3 receptor A/0.463
4j6dTESCytochrome P450 monooxygenase/0.463
4jtrIZPAldo-keto reductase family 1 member C2/0.463
4kak06UDihydrofolate reductase1.5.1.30.463
4nqgCZHMitrocomin/0.463
4psbGA3Cytokinin-specific binding protein/0.463
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.462
1dd6MCIMetallo-beta-lactamase type 2/0.462
1eq2ADQADP-L-glycero-D-manno-heptose-6-epimerase/0.462
1jjeBYSBeta-lactamase/0.462
1opbRETRetinol-binding protein 2/0.462
2am9TESAndrogen receptor/0.462
2ea2F77Methionine aminopeptidase 2/0.462
2h55DZ8Heat shock protein HSP 90-alpha/0.462
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.462
2rtiGLLStreptavidin/0.462
2ykiYKIHeat shock protein HSP 90-alpha/0.462
3vtcTK3Vitamin D3 receptor/0.462
4a81DXCMajor pollen allergen Bet v 1-A/0.462
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.462
5c4fUPGHisto-blood group ABO system transferase/0.462
5ikqJMSProstaglandin G/H synthase 21.14.99.10.462
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.461
1jtqLY3Thymidylate synthase/0.461
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.461
1pz1NAPGeneral stress protein 69/0.461
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.461
2pklDHTAndrogen receptor/0.461
2rtmIMIStreptavidin/0.461
3be2RAJVascular endothelial growth factor receptor 22.7.10.10.461
3d75NBBPheromone-binding protein ASP1/0.461
3hz137DHeat shock protein HSP 90-alpha/0.461
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3nu03TUDihydrofolate reductase1.5.1.30.461
3tkyN7I(Iso)eugenol O-methyltransferase2.1.1.1460.461
3vf60H6Glucokinase2.7.1.20.461
3wyqBTNStreptavidin/0.461
4iyg1HUStrictosidine synthase4.3.3.20.461
4l8u9AZSerum albumin/0.461
4oeaDHTAndrogen receptor/0.461
4z24FADPutative GMC-type oxidoreductase R13510.461
1dr2TAPDihydrofolate reductase1.5.1.30.460
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.460
1n71COAAac(6')-Ii protein/0.460
1xq3R18Androgen receptor/0.460
2h94FADLysine-specific histone demethylase 1A10.460
2hq9FADMll6688 protein/0.460
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
2rtoIMIStreptavidin/0.460
2xlrFADPutative flavin-containing monooxygenase/0.460
3fznD7KBenzoylformate decarboxylase4.1.1.70.460
3g1oRF1HTH-type transcriptional regulator EthR/0.460
3w5tLHPVitamin D3 receptor/0.460
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
4dz5NAPAldo-keto reductase family 1 member C3/0.460
4fgh0U6Dihydrofolate reductase1.5.1.30.460
4jq4IMNAldo-keto reductase family 1 member C2/0.460
4m9aFDAAcyl-CoA dehydrogenase/0.460
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
4ofuDHTAndrogen receptor/0.460
5jqhCAUBeta-2 adrenergic receptor/0.460
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1gs4ZK5Androgen receptor/0.459
1kwcBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.459
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.459
2fwzH71Heat shock protein HSP 90-alpha/0.459
2hasC3OVitamin D3 receptor/0.459
2pdlTOLAldose reductase1.1.1.210.459
2q7lTESAndrogen receptor/0.459
2zbaZBATrichothecene 3-O-acetyltransferase/0.459
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.459
3ghwGHWDihydrofolate reductase1.5.1.30.459
3gyuDL7Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.459
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.459
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3nx2FERFerulic acid decarboxylase/0.459
3pn1IVHDNA ligase/0.459
4b5pACOAlpha-tubulin N-acetyltransferase 1/0.459
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.459
4itfTFYVitamin D3 receptor/0.459
4mv4ACPBiotin carboxylase6.3.4.140.459
4nh82LCHeat shock protein HSP 90-alpha/0.459
5iqaGNPBifunctional AAC/APH2.3.10.459
5iu4ZMAAdenosine receptor A2a/0.459
1ndyFR3Adenosine deaminase3.5.4.40.458
1z6tADPApoptotic protease-activating factor 1/0.458
1zq5E04Aldo-keto reductase family 1 member C3/0.458
2a3iC0RMineralocorticoid receptor/0.458
2bunFADAppA protein/0.458
2e95B75Geranylgeranyl pyrophosphate synthase/0.458
2ociTYCValacyclovir hydrolase3.10.458
2pa7TYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.458
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.458
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.458
2w4qCBWProstaglandin reductase 21.3.1.480.458
3d76NBBPheromone-binding protein ASP1/0.458
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.458
3oxk5GPHistidine triad nucleotide-binding protein30.458
3vrtYS2Vitamin D3 receptor/0.458
3zrbOR8Progesterone receptor/0.458
4afgQMRAchbp/0.458
4bqg50QHeat shock protein HSP 90-alpha/0.458
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.458
4fqsLYAThymidylate synthase ThyA/0.458
4hvs647Mast/stem cell growth factor receptor Kit2.7.10.10.458
4ixgIXGDihydrofolate reductase1.5.1.30.458
4kxl6C62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.458
4xbfFADLysine-specific histone demethylase 1A10.458
4zasTYDCalS13/0.458
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.458
1swnBTNStreptavidin/0.457
1t7fDHTAndrogen receptor/0.457
2ejzSAHDiphthine synthase/0.457
2ofv242Tyrosine-protein kinase Lck2.7.10.20.457
2v1aFMNNPH1-1/0.457
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.457
3f3y4OABile salt sulfotransferase2.8.2.140.457
3hk1B64Fatty acid-binding protein, adipocyte/0.457
3stdMQ0Scytalone dehydratase4.2.1.940.457
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.457
3uweVJJAldo-keto reductase family 1 member C3/0.457
3w5q3KLVitamin D3 receptor/0.457
4eh8IRGMitogen-activated protein kinase 14/0.457
4gevCB3Thymidylate synthase/0.457
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.457
4jucTPPBenzoylformate decarboxylase4.1.1.70.457
4kxjP34Nucleoprotein/0.457
4mprTPPBenzoylformate decarboxylase4.1.1.70.457
4pztSOPHistone acetyltransferase p300/0.457
4v2gCTCTetracycline repressor protein class D/0.457
5h8tRTLRetinol-binding protein 1/0.457
4s0vSUVOrexin receptor type 2/0.457
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
1srfMTBStreptavidin/0.456
1t7rDHTAndrogen receptor/0.456
2bbqPFGThymidylate synthase/0.456
2izfBTNStreptavidin/0.456
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
3h4vDVPPteridine reductase 11.5.1.330.456
3m7rVDXVitamin D3 receptor/0.456
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.456
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.456
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.456
4ia7BIVVitamin D3 receptor A/0.456
4lsjLSJGlucocorticoid receptor/0.456
4rrhA3SProbable threonine--tRNA ligase 26.1.1.30.456
4rujVDXVitamin D3 receptor A/0.456
5hwpCOAHydroxymethylglutaryl-CoA synthase/0.456
5kf9ACOPredicted acetyltransferase/0.456
5kgjACOPredicted acetyltransferase/0.456
1osvCHCBile acid receptor/0.455
1p33MTXPteridine reductase 11.5.1.330.455
1qjgEQUSteroid Delta-isomerase5.3.3.10.455
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.455
1s36CEIObelin/0.455
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
1y56FMNUncharacterized protein/0.455
1y56FMN382aa long hypothetical sarcosine oxidase/0.455
2b8jADNClass B acid phosphatase3.1.3.20.455
2i0v6C3Macrophage colony-stimulating factor 1 receptor2.7.10.10.455
2ohvNHLGlutamate racemase/0.455
2piuDHTAndrogen receptor/0.455
2rtrIMIStreptavidin/0.455
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
2xk85R1Serine/threonine-protein kinase Nek22.7.11.10.455
3ghvGHCDihydrofolate reductase1.5.1.30.455
3h3r14HCollagen type IV alpha-3-binding protein/0.455
3htjETEbrA repressor/0.455
3mneDEXGlucocorticoid receptor/0.455
3qlrQLRDihydrofolate reductase1.5.1.30.455
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.455
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.455
3w9rA8SAbscisic acid receptor PYL9/0.455
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.455
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.455
4cavMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.455
4gm4TZDBenzoylformate decarboxylase4.1.1.70.455
4p6xHCYGlucocorticoid receptor/0.455
4wecNADShort chain dehydrogenase/0.455
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.455
1bq1CB3Thymidylate synthase/0.454
1dajMOTDihydrofolate reductase1.5.1.30.454
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.454
1s3vTQDDihydrofolate reductase1.5.1.30.454
1s3yTQTDihydrofolate reductase1.5.1.30.454
1t7mDHTAndrogen receptor/0.454
1ygjRMCPyridoxal kinase2.7.1.350.454
2b9wFADPutative aminooxidase/0.454
2bxmIMNSerum albumin/0.454
2c3oTPPPyruvate synthase/0.454
2dxiATPGlutamate--tRNA ligase6.1.1.170.454
2igxA1TPlasmepsin 2/0.454
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.454
2w71L23Biotin carboxylase6.3.4.140.454
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.454
2x7hPFNProstaglandin reductase 310.454
2xrlDXTTetracycline repressor protein class D/0.454
2zl9VDAVitamin D3 receptor/0.454
3h3t16HCollagen type IV alpha-3-binding protein/0.454
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.454
3v1s0LHStrictosidine synthase4.3.3.20.454
3v49PK0Androgen receptor/0.454
4askK0ILysine-specific demethylase 6B1.14.110.454
4bj9UHBTankyrase-22.4.2.300.454
4fflADPUncharacterized protein/0.454
4g1y0VOVitamin D3 receptor A/0.454
4g20484Vitamin D3 receptor A/0.454
4iwv1J9Glucokinase2.7.1.20.454
5aluHD2Bifunctional epoxide hydrolase 23.1.3.760.454
3uzcT4EAdenosine receptor A2a/0.454
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.453
1e26GPBDihydrofolate reductase1.5.1.30.453
1qxlFR8Adenosine deaminase3.5.4.40.453
1uydPU8Heat shock protein HSP 90-alpha/0.453
1xzqFONtRNA modification GTPase MnmE3.6.50.453
2j7dGI1Beta-glucosidase A3.2.1.210.453
2q7jTESAndrogen receptor/0.453
2rtnIMIStreptavidin/0.453
2rtqIMIStreptavidin/0.453
2wgs1AZGlutamine synthetase6.3.1.20.453
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.453
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.453
3p5sAVUCD38 molecule/0.453
3wqmB29Diterpene synthase3.1.7.80.453
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.453
4el9AFERibosomal protein S6 kinase alpha-32.7.11.10.453
4g2i0VQVitamin D3 receptor/0.453
4iah1DXAlr2278 protein/0.453
4l9q9TPSerum albumin/0.453
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.453
4rtkSAHDNA adenine methylase2.1.1.720.453
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.453
5i2fBS5Histidine triad nucleotide-binding protein 130.453
5kgpACOPredicted acetyltransferase/0.453
5uviZMAAdenosine receptor A2a/0.453
1e1qADPATP synthase subunit beta, mitochondrial3.6.3.140.452
1fwmCB3Thymidylate synthase/0.452
1h35R01Squalene--hopene cyclase4.2.1.1290.452
1k02FMNNADPH dehydrogenase 11.6.99.10.452
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.452
1umcTDP2-oxoisovalerate dehydrogenase subunit alpha1.2.4.40.452
1umcTDP2-oxoisovalerate dehydrogenase subunit beta1.2.4.40.452
2ba9FADPutative aminooxidase/0.452
2f8pCEIObelin/0.452
2rhrEMOPutative ketoacyl reductase1.3.10.452
2v59LZKBiotin carboxylase6.3.4.140.452
2w3wVG9Dihydrofolate reductase/0.452
3bbfGDPNucleoside diphosphate kinase B2.7.4.60.452
3eek53SUncharacterized protein/0.452
3gc9B45Mitogen-activated protein kinase 112.7.11.240.452
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.452
3lfcZ86Mitogen-activated protein kinase 14/0.452
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.452
3w0hW12Vitamin D3 receptor/0.452
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.452
4j0s1H3Bromodomain-containing protein 4/0.452
4j3mAJ8Tankyrase-22.4.2.300.452
4m6l21VDihydrofolate reductase1.5.1.30.452
4mt92D6Tankyrase-12.4.2.300.452
4q71FADBifunctional protein PutA/0.452
4rh10TTSpore photoproduct lyase/0.452
4yswFADXanthine dehydrogenase/oxidase/0.452
5d9j0N8Polymerase acidic protein/0.452
5iqdGNPBifunctional AAC/APH2.3.10.452
1klkPMDDihydrofolate reductase1.5.1.30.451
1nbhSAMGlycine N-methyltransferase2.1.1.200.451
1odnAPVIsopenicillin N synthase1.21.3.10.451
1oytFSNProthrombin3.4.21.50.451
1tw2ERTCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.451
1uyfPU1Heat shock protein HSP 90-alpha/0.451
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
2ab2SNLMineralocorticoid receptor/0.451
2ao6R18Androgen receptor/0.451
2aviBTNAvidin/0.451
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.451
2hz44STTyrosine-protein kinase ABL12.7.10.20.451
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.451
2uxpCLMHTH-type transcriptional regulator TtgR/0.451
2vmyFFOSerine hydroxymethyltransferase/0.451
2x9dITCTetracycline repressor protein class D/0.451
2ykeYKEHeat shock protein HSP 90-alpha/0.451
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.451
2zb8IMNProstaglandin reductase 21.3.1.480.451
2zscBTNTamavidin2/0.451
3antS82Bifunctional epoxide hydrolase 23.3.2.100.451
3c14FOKAdenylate cyclase type 2/0.451
3c14FOKAdenylate cyclase type 5/0.451
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.451
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3g4lROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3gncQQQGlutaryl-CoA dehydrogenase/0.451
3juhANPCasein kinase II subunit alpha2.7.11.10.451
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.451
3tl1JROPutative polyketide cyclase/0.451
3uleC69Actin-related protein 3/0.451
3vgnFNNSteroid Delta-isomerase5.3.3.10.451
4awo99BHeat shock protein HSP 90-alpha/0.451
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.451
4mryCEIObelin/0.451
4rtqSAHDNA adenine methylase2.1.1.720.451
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.451
1d8mBBHStromelysin-13.4.24.170.450
1f3eDPZQueuine tRNA-ribosyltransferase2.4.2.290.450
1fwkADPHomoserine kinase2.7.1.390.450
1jtuLYBThymidylate synthase/0.450
1kt3RTLRetinol-binding protein 4/0.450
1srhMOBStreptavidin/0.450
1uy9PU6Heat shock protein HSP 90-alpha/0.450
1wxjIPLTryptophan synthase alpha chain/0.450
1zdwFLVPrenyltransferase/0.450
2a84ATPPantothenate synthetase6.3.2.10.450
2bdyUNBProthrombin3.4.21.50.450
2og81N8Tyrosine-protein kinase Lck2.7.10.20.450
2p9eNAID-3-phosphoglycerate dehydrogenase1.1.1.950.450
2qe4JJ3Estrogen receptor/0.450
2rtgBTNStreptavidin/0.450
2xk3XK3Serine/threonine-protein kinase Nek22.7.11.10.450
2zlcVDXVitamin D3 receptor/0.450
3evaSAHGenome polyprotein2.1.1.560.450
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.450
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
3pd2A3SThreonine--tRNA ligase6.1.1.30.450
3pdtADPMyosin heavy chain kinase A2.7.11.70.450
3rix923Luciferin 4-monooxygenase1.13.12.70.450
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.450
3w0c6DSVitamin D3 receptor/0.450
4a9oA9OBromodomain-containing protein 2/0.450
4fgrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.450
4if5ACOAlpha-tubulin N-acetyltransferase 1/0.450
4o701QKBromodomain-containing protein 4/0.450
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.450
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.450
1bsvNDPGDP-L-fucose synthase/0.449
1hvyD16Thymidylate synthase2.1.1.450.449
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.449
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1s3uTQDDihydrofolate reductase1.5.1.30.449
1u5cBIKL-lactate dehydrogenase1.1.1.270.449
1zrb062Prothrombin3.4.21.50.449
2aa5STRMineralocorticoid receptor/0.449
2hziJINTyrosine-protein kinase ABL12.7.10.20.449
2izlIMIStreptavidin/0.449
2yeiXQIHeat shock protein HSP 90-alpha/0.449
2z52H23Geranylgeranyl pyrophosphate synthase/0.449
3d7zGK5Mitogen-activated protein kinase 14/0.449
3e92G6AMitogen-activated protein kinase 14/0.449
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.449
3gyf51PDihydrofolate reductase1.5.1.30.449
3uph0C1Genome polyprotein2.7.7.480.449
4bjbP34Tankyrase-22.4.2.300.449
4c1fX8ZMetallo-beta-lactamase type 2/0.449
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4dsbA8SAbscisic acid receptor PYL3/0.449
4edz0O5Hematopoietic prostaglandin D synthase/0.449
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4ia2BIVVitamin D3 receptor A/0.449
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.449
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.449
4rupH97Vitamin D3 receptor A/0.449
6cp4CAMCamphor 5-monooxygenase1.14.15.10.449
1ah3TOLAldose reductase1.1.1.210.448
1cjvFOKAdenylate cyclase type 2/0.448
1cjvFOKAdenylate cyclase type 5/0.448
1e92HBIPteridine reductase 11.5.1.330.448
1kceCB3Thymidylate synthase/0.448
1lluNADAlcohol dehydrogenase/0.448
1nm6L86Prothrombin3.4.21.50.448
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1ra2FOLDihydrofolate reductase1.5.1.30.448
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.448
1swtBTNStreptavidin/0.448
2bjsACVIsopenicillin N synthase1.21.3.10.448
2dw4FADLysine-specific histone demethylase 1A10.448
2ea1GPGRibonuclease I3.1.27.60.448
2ekaSAHDiphthine synthase/0.448
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.448
2g8yNADHydroxycarboxylate dehydrogenase B/0.448
2hvcLGDAndrogen receptor/0.448
2idkC2FGlycine N-methyltransferase2.1.1.200.448
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
2ji9ADPOxalyl-CoA decarboxylase4.1.1.80.448
2pixDHTAndrogen receptor/0.448
2tscCB3Thymidylate synthase/0.448
2zwaSAHtRNA wybutosine-synthesizing protein 42.1.1.2900.448
3c3eGDP2-phospho-L-lactate transferase/0.448
3drcMTXDihydrofolate reductase1.5.1.30.448
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.448
3inwJZBHeat shock protein HSP 90-alpha/0.448
3nxvD2FDihydrofolate reductase1.5.1.30.448
3ojgHL4Phosphotriesterase/0.448
3op5REBSerine/threonine-protein kinase VRK12.7.11.10.448
3qly55VUncharacterized protein/0.448
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
3vt45YIVitamin D3 receptor/0.448
4at5MUJBDNF/NT-3 growth factors receptor2.7.10.10.448
4bfvZVVPantothenate kinase2.7.1.330.448
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.448
4jubTPPBenzoylformate decarboxylase4.1.1.70.448
4k9nTZDBenzoylformate decarboxylase4.1.1.70.448
4lgaA2OAbscisic acid receptor PYL2/0.448
4oztP1AEcdysone receptor, putative/0.448
4qzuRTLRetinol-binding protein 2/0.448
4rrbA3TProbable threonine--tRNA ligase 26.1.1.30.448
4ruoBIVVitamin D3 receptor A/0.448
4udaDEXMineralocorticoid receptor/0.448
5eccNAPDehydrofolate reductase type I/0.448
4zj8SUVOrexin receptor type 1/0.448
1a8t061Metallo-beta-lactamase type 2/0.447
1buxPPSNucleoside diphosphate kinase, cytosolic2.7.4.60.447
1ddtAPUDiphtheria toxin/0.447
1dggNDPCatalase1.11.1.60.447
1dghNDPCatalase1.11.1.60.447
1kmvLIIDihydrofolate reductase1.5.1.30.447
1x8b824Wee1-like protein kinase2.7.10.20.447
1zosMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase/0.447
1zprCB3Thymidylate synthase/0.447
2clhF19Tryptophan synthase alpha chain/0.447
2e1zB4PPropionate kinase/0.447
2fzjDH3Dihydrofolate reductase1.5.1.30.447
2pd9FIDAldose reductase1.1.1.210.447
2piwDHTAndrogen receptor/0.447
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.447
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.447
3njoPYVAbscisic acid receptor PYR1/0.447
3nwlNDPCatalase1.11.1.60.447
3owj1ELCasein kinase II subunit alpha2.7.11.10.447
3qls55VDihydrofolate reductase1.5.1.30.447
4ffrATPUncharacterized protein/0.447
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4li81XQTankyrase-12.4.2.300.447
5dxjSFGHistone-arginine methyltransferase CARM1/0.447
5fitAP2Bis(5'-adenosyl)-triphosphatase3.6.1.290.447
5kf2ACOPredicted acetyltransferase/0.447
1d3gBREDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.446
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
1qoqIGPTryptophan synthase alpha chain/0.446
1thnADPAnti-sigma F factor/0.446
1u33LM2Pancreatic alpha-amylase/0.446
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.446
2ovhAS0Progesterone receptor/0.446
2rtfBTNStreptavidin/0.446
2uz2BTNAvd protein/0.446
2zlaVDBVitamin D3 receptor/0.446
3c3dFO12-phospho-L-lactate transferase/0.446
3cluFADElectron transfer flavoprotein subunit alpha/0.446
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.446
3dds26BGlycogen phosphorylase, liver form2.4.1.10.446
3havATPAminoglycoside phosphotransferase/0.446
3i68J4ZDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.446
3occDIHPurine nucleoside phosphorylase DeoD-type/0.446
3pdqKC6Lysine-specific demethylase 4A1.14.110.446
3qdd94MHeat shock protein HSP 90-alpha/0.446
3rg9WRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3vt9YI4Vitamin D3 receptor/0.446
4ag7COAGlucosamine 6-phosphate N-acetyltransferase/0.446
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.446
4b1fKRHGlutamate racemase/0.446
4bjx73BBromodomain-containing protein 4/0.446
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.446
4hy6FJ1Heat shock protein HSP 90-alpha/0.446
4jtqFLPAldo-keto reductase family 1 member C2/0.446
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.446
4qi9MTXDihydrofolate reductase/0.446
5fkkTDCTetracycline repressor protein class D/0.446
5jadFB2Platelet-activating factor acetylhydrolase3.1.1.470.446
5kjePFBAlcohol dehydrogenase E chain1.1.1.10.446
1d6w00RProthrombin3.4.21.50.445
1lbbKAIGlutamate receptor 2/0.445
1ldqSHMAvidin/0.445
1lhuESTSex hormone-binding globulin/0.445
1nbiSAMGlycine N-methyltransferase2.1.1.200.445
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.445
2b1z17MEstrogen receptor/0.445
2czcNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.590.445
2f0y3MNProtein farnesyltransferase subunit beta2.5.1.580.445
2fjdSFDAdenylylsulfate reductase, subunit A (AprA)/0.445
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.445
2ntjP1HEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2pg0FADAcyl-CoA dehydrogenase/0.445
2pivDHTAndrogen receptor/0.445
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.445
2qg2A91Heat shock protein HSP 90-alpha/0.445
2w3bNDPDihydrofolate reductase1.5.1.30.445
2wipP49Cyclin-dependent kinase 22.7.11.220.445
2y1wSFGHistone-arginine methyltransferase CARM1/0.445
2ylpTESAndrogen receptor/0.445
3aosJH2Hemolymph juvenile hormone binding protein/0.445
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.445
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.445
3g1mRF3HTH-type transcriptional regulator EthR/0.445
3hkyIX6Genome polyprotein2.7.7.480.445
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
3nxoD2BDihydrofolate reductase1.5.1.30.445
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.445
3q30D61Squalene synthase2.5.1.210.445
3seqNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.445
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.445
4bqwQNMEgl nine homolog 1/0.445
4gt8ADPSensor protein VraS2.7.13.30.445
4h6uACOAlpha-tubulin N-acetyltransferase 1/0.445
4n3l2FNProthrombin3.4.21.50.445
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.445
4rrdA3TProbable threonine--tRNA ligase 26.1.1.30.445
5cccDDFDihydrofolate reductase1.5.1.30.445
5kf8ACOPredicted acetyltransferase/0.445
1ae8AZLProthrombin3.4.21.50.444
1df8BTNStreptavidin/0.444
1yw8A75Methionine aminopeptidase 2/0.444
2e20B4PPropionate kinase/0.444
2fhlBNIAvidin-related protein 4/5/0.444
2fyuFDNCytochrome b/0.444
2fziDH3Dihydrofolate reductase1.5.1.30.444
2gjnFMNNitronate monooxygenase1.13.12.160.444
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
2hl0A3SThreonine--tRNA ligase6.1.1.30.444
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.444
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.444
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
2v95HCYCorticosteroid-binding globulin/0.444
2w3mFOLDihydrofolate reductase1.5.1.30.444
2w6pOA4Biotin carboxylase6.3.4.140.444
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.444
2xvq9DSSerum albumin/0.444
2ylqTESAndrogen receptor/0.444
3anmNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.444
3fraI2HDihydrofolate reductase1.5.1.30.444
3gb4D3MDdmC/0.444
3i6qNDPPutative leucoanthocyanidin reductase 1/0.444
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.444
3tdaPN0Cytochrome P450 2D6/0.444
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.444
3w0jT08Vitamin D3 receptor/0.444
4at2ASDPossible succinate dehydrogenase/0.444
4bcsBTNAvidin-related protein 4/5/0.444
4bw39BMBromodomain-containing protein 4/0.444
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4iae1DXAlr2278 protein/0.444
4ofrDHTAndrogen receptor/0.444
4rrkA3TProbable threonine--tRNA ligase 26.1.1.30.444
4uyg73BBromodomain-containing protein 2/0.444
1kzjCB3Thymidylate synthase/0.443
1t0iFMNNAD(P)H-dependent FMN reductase LOT6/0.443
1trgCB3Thymidylate synthase/0.443
1u3s797Estrogen receptor beta/0.443
2bjuIH4Plasmepsin-23.4.23.390.443
2c4iBTNAvidin/0.443
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.443
2g8nF83Phenylethanolamine N-methyltransferase2.1.1.280.443
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.443
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.443
2ogiGDPUncharacterized protein/0.443
2xdrNDPNAD/NADP-dependent betaine aldehyde dehydrogenase/0.443
2xpvMIYTetracycline repressor protein class D/0.443
2zi53L1Deoxycytidine kinase2.7.1.740.443
3bw4FMNPutative 2-nitropropane dioxygenase/0.443
3cr0809Wee1-like protein kinase2.7.10.20.443
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.443
3h4vNAPPteridine reductase 11.5.1.330.443
3ipuO40Oxysterols receptor LXR-alpha/0.443
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.443
3ldoANP78 kDa glucose-regulated protein/0.443
3reoEUG(Iso)eugenol O-methyltransferase2.1.1.1460.443
3vtbTKAVitamin D3 receptor/0.443
4awp99AHeat shock protein HSP 90-alpha/0.443
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.443
4g8cC6LAlpha/beta hydrolase fold protein/0.443
4gsuDWZL,D-transpeptidase 22.3.20.443
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.443
4ixd1HVIntegrin alpha-L/0.443
4j7xSASSepiapterin reductase1.1.1.1530.443
4oezDHTAndrogen receptor/0.443
4pnrG18Tankyrase-22.4.2.300.443
4tjy3GNTankyrase-22.4.2.300.443
4uohADPNucleoside diphosphate kinase/0.443
5cb3APRO-acetyl-ADP-ribose deacetylase/0.443
5dx8SFGHistone-arginine methyltransferase CARM1/0.443
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.443
5iqiGNPBifunctional AAC/APH2.3.10.443
4ea30NNNociceptin receptor/0.443
1a50FIPTryptophan synthase alpha chain/0.442
1cgkNARChalcone synthase 22.3.1.740.442
1fndA2PFerredoxin--NADP reductase, chloroplastic1.18.1.20.442
1jomFFODihydrofolate reductase1.5.1.30.442
1n5qTNCActVA 6 protein/0.442
1n5vNOMActVA 6 protein/0.442
1ot7CHCBile acid receptor/0.442
1rszDIHPurine nucleoside phosphorylase2.4.2.10.442
1trkTPPTransketolase 12.2.1.10.442
1v7aFRCAdenosine deaminase3.5.4.40.442
1wur8DGGTP cyclohydrolase 1/0.442
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.442
2bycFMNBlue-light receptor of the BLUF-family/0.442
2cftPLPPyridoxal phosphate phosphatase/0.442
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.442
2o7pNAPRiboflavin biosynthesis protein RibD/0.442
2xlsFADPutative flavin-containing monooxygenase/0.442
2xviFADPutative flavin-containing monooxygenase/0.442
3ac1KZITyrosine-protein kinase Lck2.7.10.20.442
3akzGSUGlutamate--tRNA ligase 2/0.442
3b9lAZZSerum albumin/0.442
3biy01KHistone acetyltransferase p300/0.442
3kb0A8SAbscisic acid receptor PYL2/0.442
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3tk3CPZCytochrome P450 2B41.14.14.10.442
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.442
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.442
3w5p4OAVitamin D3 receptor/0.442
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.442
4ap1NAPSteroid monooxygenase/0.442
4ayy9MXProthrombin3.4.21.50.442
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
4do30LAFatty-acid amide hydrolase 13.5.1.990.442
4eqwCOACoenzyme A disulfide reductase/0.442
4g2wNI0cGMP-specific 3',5'-cyclic phosphodiesterase/0.442
4h9814QUncharacterized protein/0.442
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.442
4i5xFLFAldo-keto reductase family 1 member B101.1.10.442
4iarERM5-hydroxytryptamine receptor 1B/0.442
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.442
4ugaH4BNitric oxide synthase oxygenase1.14.13.1650.442
1dhiMTXDihydrofolate reductase1.5.1.30.441
1drbMTXDihydrofolate reductase1.5.1.30.441
1dreMTXDihydrofolate reductase1.5.1.30.441
1eveE20Acetylcholinesterase3.1.1.70.441
1getNAPGlutathione reductase1.8.1.70.441
1i05LTLMajor urinary protein 6/0.441
1kdmDHTSex hormone-binding globulin/0.441
1kmsLIHDihydrofolate reductase1.5.1.30.441
1mczRMNBenzoylformate decarboxylase4.1.1.70.441
1piwNAPNADP-dependent alcohol dehydrogenase 61.1.1.20.441
1rx8NAPDihydrofolate reductase1.5.1.30.441
1swpBTQStreptavidin/0.441
1v93FADMethylenetetrahydrofolate reductase/0.441
2adaHPRAdenosine deaminase3.5.4.40.441
2fzhDH1Dihydrofolate reductase1.5.1.30.441
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.441
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.441
2x1eX1EAcyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form2.3.1.1640.441
2xvhFADPutative flavin-containing monooxygenase/0.441
3cqeP91Wee1-like protein kinase2.7.10.20.441
3gl2D3MDdmC/0.441
3mddFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.441
3p0eBAUUridine phosphorylase 22.4.2.30.441
3pahXDEPhenylalanine-4-hydroxylase1.14.16.10.441
3qlzQLZUncharacterized protein/0.441
3wypBSOStreptavidin/0.441
4a2jAS0Progesterone receptor/0.441
4azwATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD/0.441
4bx7B4FStreptavidin/0.441
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.441
4gi40EXQueuine tRNA-ribosyltransferase2.4.2.290.441
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.441
4hxn1A7Bromodomain-containing protein 4/0.441
4k4eK4ETankyrase-12.4.2.300.441
4kp71UQ1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.441
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.441
4oeyDHTAndrogen receptor/0.441
4y8wSTRSteroid 21-hydroxylase/0.441
4zu44TGWxcM-like protein/0.441
5irnADPNucleotide binding oligomerization domain containing 2/0.441
5k2dZMAAdenosine receptor A2a/0.441
4ug2NGIAdenosine receptor A2a/0.441
1e2nRCAThymidine kinase/0.440
1g28FMNPHY3/0.440
1g9bBABBotulinum neurotoxin type B3.4.24.690.440
1ia1NDPDihydrofolate reductase1.5.1.30.440
1t85CAMCamphor 5-monooxygenase1.14.15.10.440
1tkaN3TTransketolase 12.2.1.10.440
1uymPU3Heat shock protein HSP 90-beta/0.440
1v5eFADPyruvate oxidase/0.440
1w1sEMUCytokinin dehydrogenase 11.5.99.120.440
1y6rMTM5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.440
1yqzCOACoenzyme A disulfide reductase/0.440
1zky689Estrogen receptor/0.440
2b03TUDPhospholipase A2, major isoenzyme3.1.1.40.440
2bxoOPBSerum albumin/0.440
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2kwiGNPRas-related protein Ral-B/0.440
2qo6CHDFatty acid-binding protein 10-A, liver basic/0.440
2r6jNDPEugenol synthase 11.1.1.3180.440
2rewREWPeroxisome proliferator-activated receptor alpha/0.440
2wmdZZ0NmrA-like family domain-containing protein 1/0.440
2zzaFOLDihydrofolate reductase/0.440
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3d74NBBPheromone-binding protein ASP1/0.440
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3fowIMHPurine nucleoside phosphorylase/0.440
3g7jGTXGlutathione transferase GST1-4/0.440
3gtsD3MDdmC/0.440
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.440
3llaACPMyosin heavy chain kinase A2.7.11.70.440
3qlxQLRUncharacterized protein/0.440
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.440
4awq592Heat shock protein HSP 90-alpha/0.440
4b4w9L9Bifunctional protein FolD/0.440
4fkxCDPNucleoside diphosphate kinase/0.440
4fx9COACoenzyme A disulfide reductase1.8.1.140.440
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
4gd40WSLysine-specific demethylase 4A1.14.110.440
4h9753SDihydrofolate reductase1.5.1.30.440
4iwc1GVEstrogen receptor/0.440
4ku5DCC3-oxoacyl-[ACP] synthase III/0.440
4l23X6KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.440
4nbb9CATerminal oxygenase component of carbazole/0.440
4nbjD3YD-tyrosyl-tRNA(Tyr) deacylase/0.440
4qa0SHHHistone deacetylase 83.5.1.980.440
4qbiAP5Adenylate kinase/0.440
4uajFADNa(+)-translocating NADH-quinone reductase subunit F/0.440
5dcyNAPIridoid synthase1.3.1.990.440
4n4wSNTSmoothened homolog/0.440