Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1m2q | MNX | Casein kinase II subunit alpha | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1m2q | MNX | Casein kinase II subunit alpha | 2.7.11.1 | 1.000 | |
| 3be9 | P04 | Casein kinase II subunit alpha | 2.7.11.1 | 0.634 | |
| 1lp4 | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.625 | |
| 4dgm | AGI | Casein kinase II subunit alpha | 2.7.11.1 | 0.624 | |
| 4dgo | 0JW | Casein kinase II subunit alpha | 2.7.11.1 | 0.624 | |
| 2pvl | P55 | Casein kinase II subunit alpha | 2.7.11.1 | 0.608 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.599 | |
| 2pvh | P19 | Casein kinase II subunit alpha | 2.7.11.1 | 0.589 | |
| 1m2r | MNY | Casein kinase II subunit alpha | 2.7.11.1 | 0.588 | |
| 3at3 | ATK | Casein kinase II subunit alpha | 2.7.11.1 | 0.579 | |
| 4anm | WUL | Casein kinase II subunit alpha | 2.7.11.1 | 0.568 | |
| 1day | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.567 | |
| 4dgn | LU2 | Casein kinase II subunit alpha | 2.7.11.1 | 0.560 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.558 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.544 | |
| 1om1 | IQA | Casein kinase II subunit alpha | 2.7.11.1 | 0.541 | |
| 3q9x | EMO | Casein kinase II subunit alpha | 2.7.11.1 | 0.527 | |
| 4gub | 0Y4 | Casein kinase II subunit alpha | 2.7.11.1 | 0.526 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.522 | |
| 1daw | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.519 | |
| 2pvj | P44 | Casein kinase II subunit alpha | 2.7.11.1 | 0.517 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.517 | |
| 1m2p | HNA | Casein kinase II subunit alpha | 2.7.11.1 | 0.514 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.514 | |
| 3ofm | 4B0 | Casein kinase II subunit alpha' | 2.7.11.1 | 0.513 | |
| 2vz6 | FEF | Calcium/calmodulin-dependent protein kinase type II subunit alpha | 2.7.11.17 | 0.508 | |
| 3owk | 18E | Casein kinase II subunit alpha | 2.7.11.1 | 0.506 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.504 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.503 | |
| 4mwh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.502 | |
| 1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.499 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.497 | |
| 3nsz | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.495 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.494 | |
| 4fi1 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.494 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.491 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.491 | |
| 3q9z | TXQ | Casein kinase II subunit alpha | 2.7.11.1 | 0.491 | |
| 5csh | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.491 | |
| 3cd3 | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.490 | |
| 2iw9 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.488 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.485 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.484 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.484 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.484 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.484 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.484 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.484 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.483 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.482 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.481 | |
| 4eok | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.481 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.479 | |
| 4g17 | 0VN | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.478 | |
| 4mf0 | 29Z | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.478 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 2hy8 | 1ST | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.477 | |
| 2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.477 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.476 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.476 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.476 | |
| 2pvm | P29 | Casein kinase II subunit alpha | 2.7.11.1 | 0.475 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.474 | |
| 2zdu | 446 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.474 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.474 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.474 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.474 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.473 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.472 | |
| 2xj1 | XJ1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.472 | |
| 4e4m | 0NH | Tyrosine-protein kinase JAK2 | / | 0.472 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.471 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.471 | |
| 2w05 | FRT | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 4iva | 1J5 | Tyrosine-protein kinase JAK2 | / | 0.471 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.470 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.470 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 2x2l | X2L | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.470 | |
| 3axw | TID | Casein kinase II subunit alpha | 2.7.11.1 | 0.470 | |
| 3u4u | LNH | Casein kinase II subunit alpha | 2.7.11.1 | 0.470 | |
| 3at4 | CCK | Casein kinase II subunit alpha | 2.7.11.1 | 0.469 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.469 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.468 | |
| 2x2k | X2K | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.468 | |
| 3rk5 | 07Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.468 | |
| 3zc6 | VFC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.468 | |
| 4e73 | 0NR | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.468 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.467 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 4cki | ADN | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.467 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.466 | |
| 3ddq | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.466 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.465 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.465 | |
| 4bgg | 844 | Activin receptor type-1 | 2.7.11.30 | 0.465 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.465 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.464 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 1q5k | TMU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.464 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.464 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.464 | |
| 3v3v | MYU | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.464 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.464 | |
| 5drd | ATP | Aurora kinase A | 2.7.11.1 | 0.464 | |
| 3gxl | QIG | TGF-beta receptor type-1 | 2.7.11.30 | 0.463 | |
| 3uli | 1N3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4bie | IE6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.463 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.463 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 2eva | ADN | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.462 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.462 | |
| 2ivv | PP1 | Proto-oncogene tyrosine-protein kinase receptor Ret | 2.7.10.1 | 0.462 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.462 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.462 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.462 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1pkd | UCN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.461 | |
| 3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.461 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.461 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.460 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.460 | |
| 3dog | NNN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.460 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4fkw | 62K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1ogu | ST8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 1vjy | 460 | TGF-beta receptor type-1 | 2.7.11.30 | 0.459 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.459 | |
| 4hge | 15V | Tyrosine-protein kinase JAK2 | / | 0.459 | |
| 1h1q | 2A6 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.458 | |
| 2uzb | C75 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3r9h | Z67 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.458 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.458 | |
| 4hvi | 19S | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.458 | |
| 4mq2 | 2C4 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.458 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.458 | |
| 5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.458 | |
| 1ol5 | ADP | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 3ddp | RC8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3hzt | J60 | Calmodulin-like domain protein kinase isoform 3 | / | 0.457 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.457 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.457 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.457 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.457 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.457 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.456 | |
| 4bco | T6Q | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.456 | |
| 4gfo | 0X2 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.456 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 1fp2 | HMO | Isoflavone-7-O-methyltransferase 8 | 2.1.1.150 | 0.455 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.455 | |
| 4hvg | 19Q | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.455 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.454 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.454 | |
| 3mfu | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.454 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.454 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.454 | |
| 3qqk | X02 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.454 | |
| 4o0w | ADN | Aurora kinase A | 2.7.11.1 | 0.454 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.454 | |
| 5e8y | STU | TGF-beta receptor type-2 | 2.7.11.30 | 0.454 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 3qu0 | X40 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 3uyt | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.453 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.453 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 4jia | 1K3 | Tyrosine-protein kinase JAK2 | / | 0.453 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.453 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.453 | |
| 1csn | ATP | Casein kinase I homolog 1 | 2.7.11.1 | 0.452 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 3oro | AGS | Serine/threonine protein kinase | / | 0.452 | |
| 4im0 | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.452 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.452 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.451 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 2i51 | FMN | Pyridoxamine 5'-phosphate oxidase-related, FMN-binding | / | 0.451 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.451 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4g16 | 0VM | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.451 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.451 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.450 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.450 | |
| 1gij | 2PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 1u59 | STU | Tyrosine-protein kinase ZAP-70 | 2.7.10.2 | 0.450 | |
| 2euf | LQQ | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.450 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.450 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.450 | |
| 2vuw | 5ID | Serine/threonine-protein kinase haspin | 2.7.11.1 | 0.450 | |
| 3hll | I45 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.450 | |
| 3pgq | GY3 | Acetyl-CoA carboxylase | / | 0.450 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.450 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.450 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.450 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1kvu | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.449 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2uzl | C94 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2xmy | CDK | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3a3b | RBF | Lumazine protein | / | 0.449 | |
| 3f69 | XDR | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.449 | |
| 3i4b | Z48 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.449 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.449 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4kik | KSA | Inhibitor of nuclear factor kappa-B kinase subunit beta | 2.7.11.10 | 0.449 | |
| 5itz | GTP | Tubulin alpha-1B chain | / | 0.449 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.448 | |
| 2i40 | BLZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.448 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.448 | |
| 3cbl | STU | Tyrosine-protein kinase Fes/Fps | 2.7.10.2 | 0.448 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.448 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3say | OFT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 3uzp | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.448 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 4o0s | ADN | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 5dos | ATP | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 1nvr | STU | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 1pye | PM1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2b52 | D42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2bhh | RYU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.447 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2j9m | PY8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2pmo | HMD | Protein kinase 7 | / | 0.447 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.447 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.447 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.447 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.447 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 1yvj | 4ST | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.446 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.446 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.446 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 3gob | HXX | DdmC | / | 0.446 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.446 | |
| 3ma3 | 01I | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3rpv | 26Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.446 | |
| 4hnc | 0UT | Mandelate racemase | / | 0.446 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 4ks8 | B49 | Serine/threonine-protein kinase PAK 6 | 2.7.11.1 | 0.446 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.446 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.445 | |
| 3rak | 03Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3s1h | 56Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3she | I85 | MAP kinase-activated protein kinase 3 | 2.7.11.1 | 0.445 | |
| 3vw6 | IM6 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.445 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.445 | |
| 4eon | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.445 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.445 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.445 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.444 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 2xik | J60 | Serine/threonine-protein kinase 25 | 2.7.11.1 | 0.444 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 3wow | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.444 | |
| 4g2r | H1L | Probable propionyl-CoA carboxylase beta chain 6 | 6.4.1.3 | 0.444 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.444 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.443 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.443 | |
| 2c6t | DT5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 2pe2 | 464 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 2uze | C95 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.443 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.443 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.443 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.443 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4gih | 0X5 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.443 | |
| 4wsq | KSA | AP2-associated protein kinase 1 | 2.7.11.1 | 0.443 | |
| 1c70 | L75 | Protease | / | 0.442 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.442 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.442 | |
| 1xny | BTN | Propionyl-CoA carboxylase complex B subunit | / | 0.442 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.442 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.442 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2iw6 | QQ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 3rvg | 17P | Tyrosine-protein kinase JAK2 | / | 0.442 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4bcp | T3C | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4eor | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 4g1w | G1W | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.442 | |
| 4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 4lrj | ANP | Uncharacterized protein | / | 0.442 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.441 | |
| 1k6p | XN3 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.441 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 3cgf | JNF | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 3iok | 1P6 | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.441 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.441 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.441 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.441 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.441 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.440 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1q3w | ATU | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 1uv5 | BRW | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 1v1k | 3FP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.440 | |
| 2x9f | X9F | Ephrin type-B receptor 4 | 2.7.10.1 | 0.440 | |
| 2xgo | ZKD | Uncharacterized protein | / | 0.440 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3llt | ANP | Protein serine/threonine kinase-1 | / | 0.440 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.440 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4yuq | KS1 | Calmodulin-like domain protein kinase | / | 0.440 |