sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1lkd	BP6	Biphenyl-2,3-diol 1,2-dioxygenase	1.13.11.39

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1lkd	BP6	Biphenyl-2,3-diol 1,2-dioxygenase	1.13.11.39	1.000
1lgt	BP3	Biphenyl-2,3-diol 1,2-dioxygenase	1.13.11.39	0.668
1kmy	BPY	Biphenyl-2,3-diol 1,2-dioxygenase	1.13.11.39	0.507
4lxj	LAN	Lanosterol 14-alpha demethylase	1.14.13.70	0.474
2ejv	NAD	L-threonine 3-dehydrogenase	/	0.456
5hs1	VOR	Lanosterol 14-alpha demethylase	/	0.452
3nxx	NDP	Dihydrofolate reductase	1.5.1.3	0.451
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.445
4e0u	0MV	Cyclic dipeptide N-prenyltransferase	/	0.445
4g3j	VNT	Lanosterol 14-alpha-demethylase	/	0.444
3gfb	NAD	L-threonine 3-dehydrogenase	/	0.443