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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1lhwESMSex hormone-binding globulin

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1lhwESMSex hormone-binding globulin/1.000
1d2sDHTSex hormone-binding globulin/0.546
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.512
3gwfFADCyclohexanone monooxygenase/0.505
1jioDEB6-deoxyerythronolide B hydroxylase/0.499
1lhvNOGSex hormone-binding globulin/0.495
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.493
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.493
1osvCHCBile acid receptor/0.492
3cv9VDXVitamin D3 dihydroxylase/0.491
4ubsDIFPentalenic acid synthase1.14.15.110.489
1iwiCAMCamphor 5-monooxygenase1.14.15.10.488
1og5SWFCytochrome P450 2C9/0.486
3qly55VUncharacterized protein/0.485
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.484
1tezHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.483
4cd2FOLDihydrofolate reductase1.5.1.30.482
1f5fDHTSex hormone-binding globulin/0.481
4xe606UDihydrofolate reductase1.5.1.30.481
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.480
4tuvCPZCytochrome P450 1191.140.480
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.479
1kl2FONSerine hydroxymethyltransferase/0.478
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.478
1qnfHDFDeoxyribodipyrimidine photo-lyase4.1.99.30.477
2yee2ECHeat shock protein HSP 90-alpha/0.477
3ua506XCytochrome P450 2B61.14.130.477
2xgoZKDUncharacterized protein/0.475
1fmjRTLRetinol dehydratase/0.474
2xh9J01Uncharacterized protein/0.473
3inwJZBHeat shock protein HSP 90-alpha/0.473
3p8iFMNPentaerythritol tetranitrate reductase/0.473
1k6pXN3Gag-Pol polyprotein3.4.23.160.472
2qboCAMCamphor 5-monooxygenase1.14.15.10.472
3tjsD0RCytochrome P450 3A4/0.472
1dz6CAMCamphor 5-monooxygenase1.14.15.10.471
1eupASD6-deoxyerythronolide B hydroxylase/0.471
3koo24DBifunctional epoxide hydrolase 23.3.2.100.471
3mdvCL6Cholesterol 24-hydroxylase/0.471
3nr4PYVAbscisic acid receptor PYL2/0.471
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.471
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.471
1blzACVIsopenicillin N synthase1.21.3.10.470
2fpcSCGStrictosidine synthase4.3.3.20.470
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.470
4oqyNDP(S)-imine reductase/0.470
4ryvZEAProtein LlR18A/0.469
2y30SM8Putative repressor SimReg2/0.468
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.468
3s79ASDAromatase1.14.14.140.468
3vtdTKDVitamin D3 receptor/0.468
4h9753SDihydrofolate reductase1.5.1.30.468
1iyzNDPProbable quinone oxidoreductase/0.467
1wc0APCAdenylate cyclase/0.467
2hw2RFPRifampin ADP-ribosyl transferase/0.467
2z97CAMCamphor 5-monooxygenase1.14.15.10.467
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.466
1jlcFTCGag-Pol polyprotein2.7.7.490.466
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.465
2j5xGSPADP-ribosylation factor 6/0.465
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.465
3eek53SUncharacterized protein/0.465
4y8wSTRSteroid 21-hydroxylase/0.465
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.464
2cd2FOLDihydrofolate reductase1.5.1.30.464
2vssACOHydroxycinnamoyl-CoA hydratase-lyase4.1.2.410.464
3jw5TOPDihydrofolate reductase/0.464
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.464
4f700STCyclin-dependent kinase 82.7.11.220.464
1fmlRTLRetinol dehydratase/0.463
1phgMYTCamphor 5-monooxygenase1.14.15.10.463
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.463
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.463
3bfb9ODPheromone-binding protein ASP1/0.463
3fwjCAMCamphor 5-monooxygenase1.14.15.10.463
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.463
3opdHIEHeat shock protein 83/0.463
3q30D61Squalene synthase2.5.1.210.463
4l8u9AZSerum albumin/0.463
1ybgTAVUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.462
3cseN22Uncharacterized protein/0.462
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.462
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
4nh82LCHeat shock protein HSP 90-alpha/0.462
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.462
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.461
2ittAEEEpidermal growth factor receptor2.7.10.10.461
2y3rTRKTamL/0.461
2zb45OPProstaglandin reductase 21.3.1.480.461
3nj0PYVAbscisic acid receptor PYL2/0.461
3t3q9PLCytochrome P450 2A61.14.130.461
4l4cCAMCamphor 5-monooxygenase1.14.15.10.461
4mlhVO2Glucokinase2.7.1.20.461
5cccDDFDihydrofolate reductase1.5.1.30.461
1al7HSTPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.460
1pl8NADSorbitol dehydrogenase1.1.1.140.460
2vn0TDZCytochrome P450 2C8/0.460
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.460
3jw3TOPDihydrofolate reductase/0.460
3vt7VDXVitamin D3 receptor/0.460
3vtcTK3Vitamin D3 receptor/0.460
4ejgNCTCytochrome P450 2A131.14.14.10.460
1dz8CAMCamphor 5-monooxygenase1.14.15.10.459
1nq7ARLNuclear receptor ROR-beta/0.459
1t85CAMCamphor 5-monooxygenase1.14.15.10.459
1z6tADPApoptotic protease-activating factor 1/0.459
2acwUPGGlycosyltransferase/0.459
3lanKBTGag-Pol polyprotein2.7.7.490.459
3mdmFJZCholesterol 24-hydroxylase/0.459
3ns2PYVAbscisic acid receptor PYL2/0.459
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.459
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4wloNAIMalate dehydrogenase, mitochondrial1.1.1.370.459
2m56CAMCamphor 5-monooxygenase1.14.15.10.458
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
3h18PMSEsterase/lipase/0.458
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
3vt9YI4Vitamin D3 receptor/0.458
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.458
4g1z0VPVitamin D3 receptor A/0.458
4jv618FRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.458
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.458
4wa9AXITyrosine-protein kinase ABL12.7.10.20.458
1iwjCAMCamphor 5-monooxygenase1.14.15.10.457
1jipKTN6-deoxyerythronolide B hydroxylase/0.457
1uzwCDHIsopenicillin N synthase1.21.3.10.457
2qblCAMCamphor 5-monooxygenase1.14.15.10.457
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.457
2xvu9DNSerum albumin/0.457
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.457
3pe2E1BCasein kinase II subunit alpha2.7.11.10.457
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.457
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
4c9pCAMCytochrome P450/0.457
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.457
4ead0NPThymidine phosphorylase2.4.2.40.457
4i2pG73Gag-Pol polyprotein2.7.7.490.457
5eg3ACPFibroblast growth factor receptor 2/0.457
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.456
2ev9NAPShikimate dehydrogenase (NADP(+))/0.456
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.456
2w3vTOPDihydrofolate reductase/0.456
2xvv9DNSerum albumin/0.456
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.456
3zv5BPYCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.456
4h9614QDihydrofolate reductase1.5.1.30.456
4j16NADNAD/NADP transhydrogenase alpha subunit 1/0.456
4ndnSAMS-adenosylmethionine synthase isoform type-22.5.1.60.456
5ifyUMPGlucose-1-phosphate thymidylyltransferase/0.456
1chwHXCChalcone synthase 22.3.1.740.455
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.455
2bu9HFVIsopenicillin N synthase1.21.3.10.455
3d0bSNXHeat shock protein HSP 90-alpha/0.455
3fsuC2F5,10-methylenetetrahydrofolate reductase1.5.1.200.455
3inxJZCHeat shock protein HSP 90-alpha/0.455
3u4cNDPNADPH-dependent reductase BacG/0.455
4iui1GQEstrogen receptor/0.455
4j6dTESCytochrome P450 monooxygenase/0.455
1i58ACPChemotaxis protein CheA2.7.13.30.454
1tdrMTXDihydrofolate reductase1.5.1.30.454
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.454
2bxmIMNSerum albumin/0.454
3a0iAJIGlucokinase2.7.1.20.454
3fwiCAMCamphor 5-monooxygenase1.14.15.10.454
3saz043Malate synthase G/0.454
4ejh0QACytochrome P450 2A131.14.14.10.454
4qa0SHHHistone deacetylase 83.5.1.980.454
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
1dkfBMSRetinoic acid receptor alpha/0.453
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.453
1t88CAMCamphor 5-monooxygenase1.14.15.10.453
2cppCAMCamphor 5-monooxygenase1.14.15.10.453
2j0dERYCytochrome P450 3A4/0.453
3a1nNADNDP-sugar epimerase/0.453
3dhoB2MStreptogramin A acetyltransferase2.3.10.453
3gwfNAPCyclohexanone monooxygenase/0.453
3qlrNDPDihydrofolate reductase1.5.1.30.453
3vs3VSETyrosine-protein kinase HCK2.7.10.20.453
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.453
4nb6444Nuclear receptor ROR-gamma/0.453
4ubuCOASteroid 3-ketoacyl-CoA thiolase/0.453
4wlvNADMalate dehydrogenase, mitochondrial1.1.1.370.453
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.453
1ek2CDUBifunctional epoxide hydrolase 2/0.452
1enzNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
1j39UPGDNA beta-glucosyltransferase/0.452
1zeoC01Peroxisome proliferator-activated receptor gamma/0.452
2hcdBIVVitamin D3 receptor A/0.452
2jn3JN3Fatty acid-binding protein, liver/0.452
2rkvZBATrichothecene 3-O-acetyltransferase/0.452
2x7gPVBSRSF protein kinase 22.7.11.10.452
3bfa9ODOdorant binding protein ASP1/0.452
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.452
4h9814QUncharacterized protein/0.452
3pwhZMAAdenosine receptor A2a/0.452
1k6cMK1Gag-Pol polyprotein3.4.23.160.451
1k6tXN1Gag-Pol polyprotein3.4.23.160.451
1mvsDTMDihydrofolate reductase1.5.1.30.451
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.451
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2aqiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.451
2lbaCHOFatty acid binding protein 6/0.451
2zbaZBATrichothecene 3-O-acetyltransferase/0.451
3dmhSAMProbable ribosomal RNA small subunit methyltransferase/0.451
3imxB84Glucokinase2.7.1.20.451
3r34COA4-hydroxybenzoyl-CoA thioesterase3.1.2.230.451
4c717RD3-oxoacyl-ACP synthase/0.451
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4iteTEYVitamin D3 receptor/0.451
4r20AERCytochrome P450 family 17 polypeptide 2/0.451
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
1ictT44Transthyretin/0.450
1m13HYFNuclear receptor subfamily 1 group I member 2/0.450
1os1ATPPhosphoenolpyruvate carboxykinase (ATP)/0.450
1v9aSAHUncharacterized protein/0.450
2bbqPFGThymidylate synthase/0.450
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
2ociTYCValacyclovir hydrolase3.10.450
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.450
3gwlFADFAD-linked sulfhydryl oxidase1.8.3.20.450
3mnrSD1Heat shock protein HSP 90-alpha/0.450
3qlhT27Gag-Pol polyprotein2.7.7.490.450
3qlrQLRDihydrofolate reductase1.5.1.30.450
3sh25DRDihydrofolate reductase1.5.1.30.450
3sp9IL2Peroxisome proliferator-activated receptor delta/0.450
4gncASORegucalcin3.1.1.170.450
4jqh1MFAlr2278 protein/0.450
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.450
4pd6URINucleoside permease/0.450
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
1g4sTPSThiamine-phosphate synthase/0.449
1nooCAHCamphor 5-monooxygenase1.14.15.10.449
1phePIYCamphor 5-monooxygenase1.14.15.10.449
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1s0zEB1Vitamin D3 receptor/0.449
1v59NADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.449
2i1m5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.449
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.449
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.449
3cgeNDPCoenzyme A disulfide reductase/0.449
3ddw055Glycogen phosphorylase, liver form2.4.1.10.449
3deyDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
3klmDHTEstradiol 17-beta-dehydrogenase 11.1.1.620.449
3r324CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.449
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.449
3zhqTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.449
4pd5GEONucleoside permease/0.449
5br4NADLactaldehyde reductase1.1.1.770.449
5kgpACOPredicted acetyltransferase/0.449
6cp4CAMCamphor 5-monooxygenase1.14.15.10.449
1gebCAMCamphor 5-monooxygenase1.14.15.10.448
1jutLYDThymidylate synthase/0.448
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.448
2a1mCAMCamphor 5-monooxygenase1.14.15.10.448
2fziDH3Dihydrofolate reductase1.5.1.30.448
2gjlFMNNitronate monooxygenase1.13.12.160.448
2tpsTPSThiamine-phosphate synthase/0.448
2xgs44PUncharacterized protein/0.448
2zaxCAMCamphor 5-monooxygenase1.14.15.10.448
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.448
3oquA8SAbscisic acid receptor PYL9/0.448
3r3d4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.448
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4dc0NDPPutative ketoacyl reductase1.3.10.448
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.448
4ia3BIVVitamin D3 receptor A/0.448
4mv4ACPBiotin carboxylase6.3.4.140.448
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.448
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
5eccNAPDehydrofolate reductase type I/0.448
1drbMTXDihydrofolate reductase1.5.1.30.447
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1lhuESTSex hormone-binding globulin/0.447
1m78CLZDihydrofolate reductase1.5.1.30.447
1rkhVD2Vitamin D3 receptor/0.447
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
2rhrEMOPutative ketoacyl reductase1.3.10.447
2y60M8FIsopenicillin N synthase1.21.3.10.447
2zbzVDXVitamin D3 dihydroxylase/0.447
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.447
3cyz9ODPheromone-binding protein ASP1/0.447
3fwfCAMCamphor 5-monooxygenase1.14.15.10.447
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
3vt5YI2Vitamin D3 receptor/0.447
3zuxTCHTransporter/0.447
4apuA2KProgesterone receptor/0.447
4awp99AHeat shock protein HSP 90-alpha/0.447
4j6cSTRCytochrome P450 monooxygenase/0.447
4l9q9TPSerum albumin/0.447
1fm4DXCMajor pollen allergen Bet v 1-L/0.446
1txiTX5Vitamin D3 receptor/0.446
2feuCAMCamphor 5-monooxygenase1.14.15.10.446
2hb8MVDVitamin D3 receptor/0.446
2vcmM11Isopenicillin N synthase1.21.3.10.446
2vzmNRBCytochrome P450 monooxygenase PikC/0.446
3frdDHFDihydrofolate reductase1.5.1.30.446
3h1vTK1Glucokinase2.7.1.20.446
3hz142CHeat shock protein HSP 90-alpha/0.446
3nszANPCasein kinase II subunit alpha2.7.11.10.446
3p3zP3ZPutative cytochrome P450/0.446
3pe6ZYHMonoglyceride lipase/0.446
3qyw6PBMitogen-activated protein kinase 12.7.11.240.446
3sa27DRDihydrofolate reductase/0.446
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.446
3vev0H4Glucokinase2.7.1.20.446
4awo99BHeat shock protein HSP 90-alpha/0.446
4b1fKRHGlutamate racemase/0.446
4cdmFO1Deoxyribodipyrimidine photolyase/0.446
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.446
4trj665Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
1bwsNDPGDP-L-fucose synthase/0.445
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.445
1kgjFL8Transthyretin/0.445
1tduCB3Thymidylate synthase/0.445
1x8lOXRRetinol dehydratase/0.445
1y0s331Peroxisome proliferator-activated receptor delta/0.445
1yinCM3Estrogen receptor/0.445
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.445
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
2po7CHDFerrochelatase, mitochondrial4.99.1.10.445
2puiADPMethylthioribose kinase2.7.1.1000.445
2ze2T27Gag-Pol polyprotein2.7.7.490.445
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.445
3cisATPUniversal stress protein Rv2623/0.445
3d574HYThyroid hormone receptor beta/0.445
3gc9B45Mitogen-activated protein kinase 112.7.11.240.445
3p8jFMNPentaerythritol tetranitrate reductase/0.445
3r374CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.445
3sai9DRDihydrofolate reductase/0.445
3vt65YIVitamin D3 receptor/0.445
4b8zNAPGDP-L-fucose synthase1.1.1.2710.445
4crsAGSSerine/threonine-protein kinase N22.7.11.130.445
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.445
4fgg0U5Dihydrofolate reductase1.5.1.30.445
4h9506UDihydrofolate reductase1.5.1.30.445
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.445
4hw219HInduced myeloid leukemia cell differentiation protein Mcl-1/0.445
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.445
4q73FADBifunctional protein PutA/0.445
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.445
4x5fFOLDihydrofolate reductase1.5.1.30.445
5hs1VORLanosterol 14-alpha demethylase/0.445
5kf1ACOPredicted acetyltransferase/0.445
1f28UMPThymidylate synthase2.1.1.450.444
1kkq471Peroxisome proliferator-activated receptor alpha/0.444
1kzjCB3Thymidylate synthase/0.444
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
1oc1ASVIsopenicillin N synthase1.21.3.10.444
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
1r9oFLPCytochrome P450 2C9/0.444
2fnaADPUncharacterized protein/0.444
2in6839Wee1-like protein kinase2.7.10.20.444
2l84J28CREB-binding protein/0.444
2om9AJAPeroxisome proliferator-activated receptor gamma/0.444
2xvw9NRSerum albumin/0.444
2znpK55Peroxisome proliferator-activated receptor delta/0.444
3cd2MTXDihydrofolate reductase1.5.1.30.444
3eej53RUncharacterized protein/0.444
3oafOAGDihydrofolate reductase1.5.1.30.444
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
3w5q3KLVitamin D3 receptor/0.444
3wrmCAMCamphor 5-monooxygenase1.14.15.10.444
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.444
3zc3NAPFerredoxin--NADP reductase1.18.1.20.444
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
4bcqTJFCyclin-dependent kinase 22.7.11.220.444
4cp4CAMCamphor 5-monooxygenase1.14.15.10.444
4qysPLRTryptophan synthase beta chain 24.2.1.200.444
1db1VDXVitamin D3 receptor/0.443
1ee9NADMethylenetetrahydrofolate dehydrogenase [NAD(+)]1.5.1.150.443
1rd4L08Integrin alpha-L/0.443
1t87CAMCamphor 5-monooxygenase1.14.15.10.443
1zprCB3Thymidylate synthase/0.443
2ghmLICMitogen-activated protein kinase 14/0.443
2hasC3OVitamin D3 receptor/0.443
2iltNN1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.443
2j0k4STFocal adhesion kinase 12.7.10.20.443
2pvnP63Casein kinase II subunit alpha2.7.11.10.443
2q9fC3SCholesterol 24-hydroxylase/0.443
2yejXQKHeat shock protein HSP 90-alpha/0.443
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3clyACPFibroblast growth factor receptor 2/0.443
3eel53TUncharacterized protein/0.443
3ictCOACoenzyme A disulfide reductase/0.443
3lqfNADGalactitol dehydrogenase/0.443
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.443
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.443
3srrQ20Dihydrofolate reductase1.5.1.30.443
3t3r9PLCytochrome P450 2A61.14.130.443
3vruYS3Vitamin D3 receptor/0.443
3vrwYS5Vitamin D3 receptor/0.443
4efuEFUHeat shock protein HSP 90-alpha/0.443
4g1d0VKVitamin D3 receptor A/0.443
4g3rCAMCamphor 5-monooxygenase1.14.15.10.443
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1fndA2PFerredoxin--NADP reductase, chloroplastic1.18.1.20.442
1mjhATPUniversal stress protein MJ0577/0.442
1pxxDIFProstaglandin G/H synthase 21.14.99.10.442
1u1f183Uridine phosphorylase2.4.2.30.442
2ejvNADL-threonine 3-dehydrogenase/0.442
2hamC33Vitamin D3 receptor/0.442
2qbmCAMCamphor 5-monooxygenase1.14.15.10.442
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.442
2y05RALProstaglandin reductase 1/0.442
3hz5Z64Heat shock protein HSP 90-alpha/0.442
3ia4MTXDihydrofolate reductase/0.442
3k145352-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.442
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.442
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.442
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.442
3sa16DRDihydrofolate reductase/0.442
3vt8YI3Vitamin D3 receptor/0.442
3w5p4OAVitamin D3 receptor/0.442
4i9i1DYTankyrase-12.4.2.300.442
4j6bPLOCytochrome P450 monooxygenase/0.442
4klrCHDFerrochelatase, mitochondrial4.99.1.10.442
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1l2jETCEstrogen receptor beta/0.441
1o5rFR9Adenosine deaminase3.5.4.40.441
1ove358Mitogen-activated protein kinase 14/0.441
1q4xG24Thyroid hormone receptor beta/0.441
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.441
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.441
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.441
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.441
2yejZZ3Heat shock protein HSP 90-alpha/0.441
2zb8IMNProstaglandin reductase 21.3.1.480.441
3ez2ADPPlasmid partition protein A/0.441
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
3is9AC7Gag-Pol polyprotein2.7.7.490.441
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.441
3qm4PN0Cytochrome P450 2D6/0.441
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.441
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.441
3w0aDS5Vitamin D3 receptor/0.441
3w5tLHPVitamin D3 receptor/0.441
4egnTWOCytochrome P450/0.441
4f9mFCMPeroxisome proliferator-activated receptor gamma/0.441
4hnc0UTMandelate racemase/0.441
4iarERM5-hydroxytryptamine receptor 1B/0.441
4j4vSVRNucleocapsid protein/0.441
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.441
4rupH97Vitamin D3 receptor A/0.441
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
1cf3FADGlucose oxidase1.1.3.40.440
1draMTXDihydrofolate reductase1.5.1.30.440
1i5cADPChemotaxis protein CheA2.7.13.30.440
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.440
1jumBERHTH-type transcriptional regulator QacR/0.440
1l3iSAHProbable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)/0.440
1nceCB3Thymidylate synthase/0.440
1q1rFADPutidaredoxin reductase1.18.1.50.440
1rx8FOLDihydrofolate reductase1.5.1.30.440
1s19MC9Vitamin D3 receptor/0.440
1uy9PU6Heat shock protein HSP 90-alpha/0.440
1x7hNDPPutative ketoacyl reductase1.3.10.440
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2hqpNDPDihydrofolate reductase1.5.1.30.440
2rh9IGPTryptophan synthase alpha chain/0.440
2uzhIPE2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.440
3csdEMOPutative ketoacyl reductase1.3.10.440
3gobHXXDdmC/0.440
3irxUDRGag-Pol polyprotein2.7.7.490.440
3l8sBFFMitogen-activated protein kinase 14/0.440
3oagLPQRenin3.4.23.150.440
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.440
4f7l0SOCyclin-dependent kinase 82.7.11.220.440
4ie5MD6Alpha-ketoglutarate-dependent dioxygenase FTO/0.440
4jia1K3Tyrosine-protein kinase JAK2/0.440
4lxhC1EAlpha/beta hydrolase fold/0.440
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.440
4p6wMOFGlucocorticoid receptor/0.440
5kghACOPredicted acetyltransferase/0.440