Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ld8U49Protein farnesyltransferase subunit beta2.5.1.58

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1ld8U49Protein farnesyltransferase subunit beta2.5.1.581.000
1s63778Protein farnesyltransferase subunit beta2.5.1.580.787
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.756
1sa4JANProtein farnesyltransferase subunit beta2.5.1.580.668
1mzcBNEProtein farnesyltransferase subunit beta2.5.1.580.619
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.604
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.601
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.599
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.581
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.581
1o1s1NHProtein farnesyltransferase subunit beta2.5.1.580.579
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.577
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.565
3e30ED4Protein farnesyltransferase subunit beta2.5.1.580.564
4gtr7TRProtein farnesyltransferase subunit beta2.5.1.580.555
3ksqZ96Protein farnesyltransferase subunit beta2.5.1.580.548
2r2lPB9Protein farnesyltransferase subunit beta2.5.1.580.529
3pz43PZProtein farnesyltransferase subunit beta2.5.1.580.506
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.485
1n4sCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.479
4gto7TOProtein farnesyltransferase subunit beta2.5.1.580.474
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.473
3q7fED2Uncharacterized protein/0.469
3sfy3FYUncharacterized protein/0.467
4gtp7TPProtein farnesyltransferase subunit beta2.5.1.580.459
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.458
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.443