sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1l2j | ETC | Estrogen receptor beta |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1l2j | ETC | Estrogen receptor beta | / | 1.000 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.482 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.452 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.450 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.445 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.441 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.441 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.440 |