sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1kkq	471	Peroxisome proliferator-activated receptor alpha

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1kkq	471	Peroxisome proliferator-activated receptor alpha	/	1.000
1k7l	544	Peroxisome proliferator-activated receptor alpha	/	0.465
2hfp	NSI	Peroxisome proliferator-activated receptor gamma	/	0.462
2i4p	DRH	Peroxisome proliferator-activated receptor gamma	/	0.451
3vjh	J35	Peroxisome proliferator-activated receptor gamma	/	0.450
3sp6	IL2	Peroxisome proliferator-activated receptor alpha	/	0.441
1fm9	570	Peroxisome proliferator-activated receptor gamma	/	0.440
1zeo	C01	Peroxisome proliferator-activated receptor gamma	/	0.440