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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ke5LS1Cyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1ke5LS1Cyclin-dependent kinase 22.7.11.221.000
1ke7LS3Cyclin-dependent kinase 22.7.11.220.644
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.639
3qzgX67Cyclin-dependent kinase 22.7.11.220.579
1ke6LS2Cyclin-dependent kinase 22.7.11.220.563
2btsU32Cyclin-dependent kinase 22.7.11.220.561
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.555
3r1yX76Cyclin-dependent kinase 22.7.11.220.549
4ek610KCyclin-dependent kinase 22.7.11.220.545
4fkq42KCyclin-dependent kinase 22.7.11.220.542
1pxmCK5Cyclin-dependent kinase 22.7.11.220.540
4fki09KCyclin-dependent kinase 22.7.11.220.540
2btrU73Cyclin-dependent kinase 22.7.11.220.539
2uzoC62Cyclin-dependent kinase 22.7.11.220.536
2c6o4SPCyclin-dependent kinase 22.7.11.220.535
1ykr628Cyclin-dependent kinase 22.7.11.220.534
1ke8LS4Cyclin-dependent kinase 22.7.11.220.530
2xmyCDKCyclin-dependent kinase 22.7.11.220.530
2vthLZ2Cyclin-dependent kinase 22.7.11.220.529
3ezvEZVCyclin-dependent kinase 22.7.11.220.528
4fkpLS5Cyclin-dependent kinase 22.7.11.220.528
1ke9LS5Cyclin-dependent kinase 22.7.11.220.527
4fkt48KCyclin-dependent kinase 22.7.11.220.524
3s2pPMUCyclin-dependent kinase 22.7.11.220.522
3lfnA27Cyclin-dependent kinase 22.7.11.220.521
1pxoCK7Cyclin-dependent kinase 22.7.11.220.520
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.520
1oitHDTCyclin-dependent kinase 22.7.11.220.519
3r83Z14Cyclin-dependent kinase 22.7.11.220.519
2a0cCK9Cyclin-dependent kinase 22.7.11.220.517
3r8lZ30Cyclin-dependent kinase 22.7.11.220.517
3s1h56ZCyclin-dependent kinase 22.7.11.220.517
2w05FRTCyclin-dependent kinase 22.7.11.220.514
1g5sI17Cyclin-dependent kinase 22.7.11.220.512
4kd11QKCyclin-dependent kinase 22.7.11.220.508
3r7yZ04Cyclin-dependent kinase 22.7.11.220.504
1y91CT9Cyclin-dependent kinase 22.7.11.220.503
1w8cN69Cyclin-dependent kinase 22.7.11.220.500
3qtxX43Cyclin-dependent kinase 22.7.11.220.500
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.498
1gih1PUCyclin-dependent kinase 22.7.11.220.496
1urwI1PCyclin-dependent kinase 22.7.11.220.496
3sw418KCyclin-dependent kinase 22.7.11.220.496
2vu3LZECyclin-dependent kinase 22.7.11.220.495
1di8DTQCyclin-dependent kinase 22.7.11.220.494
4acm7YGCyclin-dependent kinase 22.7.11.220.492
4bgh3I6Cyclin-dependent kinase 22.7.11.220.492
4fkv61KCyclin-dependent kinase 22.7.11.220.492
1b38ATPCyclin-dependent kinase 22.7.11.220.490
3qqlX03Cyclin-dependent kinase 22.7.11.220.488
3r8vZ62Cyclin-dependent kinase 22.7.11.220.488
1ckpPVBCyclin-dependent kinase 22.7.11.220.487
3rm719ZCyclin-dependent kinase 22.7.11.220.487
3iggEFQCyclin-dependent kinase 22.7.11.220.486
3rpo24ZCyclin-dependent kinase 22.7.11.220.486
4ek816KCyclin-dependent kinase 22.7.11.220.486
1w0xOLOCyclin-dependent kinase 22.7.11.220.485
2w06FRVCyclin-dependent kinase 22.7.11.220.485
3qtuX44Cyclin-dependent kinase 22.7.11.220.485
1gii1PUCyclin-dependent kinase 22.7.11.220.484
2uznC96Cyclin-dependent kinase 22.7.11.220.484
1pxlCK4Cyclin-dependent kinase 22.7.11.220.483
2a4lRRCCyclin-dependent kinase 22.7.11.220.483
3rak03ZCyclin-dependent kinase 22.7.11.220.482
3lfqA28Cyclin-dependent kinase 22.7.11.220.481
3r9dX6BCyclin-dependent kinase 22.7.11.220.481
3rjc06ZCyclin-dependent kinase 22.7.11.220.480
3rk708ZCyclin-dependent kinase 22.7.11.220.480
3rkb12ZCyclin-dependent kinase 22.7.11.220.480
2vttLZDCyclin-dependent kinase 22.7.11.220.479
3rk909ZCyclin-dependent kinase 22.7.11.220.479
1oirHDYCyclin-dependent kinase 22.7.11.220.478
2b52D42Cyclin-dependent kinase 22.7.11.220.478
3qu0X40Cyclin-dependent kinase 22.7.11.220.478
3r7vZ02Cyclin-dependent kinase 22.7.11.220.478
3sqq99ZCyclin-dependent kinase 22.7.11.220.478
3r1sX73Cyclin-dependent kinase 22.7.11.220.476
4fkj11KCyclin-dependent kinase 22.7.11.220.475
2b53D23Cyclin-dependent kinase 22.7.11.220.474
2r3mSCXCyclin-dependent kinase 22.7.11.220.474
3rpv26ZCyclin-dependent kinase 22.7.11.220.474
2w1hL0FCyclin-dependent kinase 22.7.11.220.471
2fvdLIACyclin-dependent kinase 22.7.11.220.470
2r64740Cyclin-dependent kinase 22.7.11.220.470
4fkg4CKCyclin-dependent kinase 22.7.11.220.470
3qwjX6ACyclin-dependent kinase 22.7.11.220.469
3qxoX65Cyclin-dependent kinase 22.7.11.220.469
1hckATPCyclin-dependent kinase 22.7.11.220.468
2exmZIPCyclin-dependent kinase 22.7.11.220.468
2r3jSCJCyclin-dependent kinase 22.7.11.220.468
2r3lSCWCyclin-dependent kinase 22.7.11.220.468
3wblPDYCyclin-dependent kinase 22.7.11.220.468
3raiX85Cyclin-dependent kinase 22.7.11.220.467
2w17I19Cyclin-dependent kinase 22.7.11.220.465
3r71X86Cyclin-dependent kinase 22.7.11.220.465
3roy22ZCyclin-dependent kinase 22.7.11.220.465
4fks46KCyclin-dependent kinase 22.7.11.220.465
2r3iSCFCyclin-dependent kinase 22.7.11.220.464
3rni21ZCyclin-dependent kinase 22.7.11.220.464
2vv9IM9Cyclin-dependent kinase 22.7.11.220.463
3fz1B98Cyclin-dependent kinase 22.7.11.220.463
2r3r6SCCyclin-dependent kinase 22.7.11.220.462
3r7uX96Cyclin-dependent kinase 22.7.11.220.462
3ral04ZCyclin-dependent kinase 22.7.11.220.462
3rm618ZCyclin-dependent kinase 22.7.11.220.462
4bcmT7ZCyclin-dependent kinase 22.7.11.220.461
4ez30S0Cyclin-dependent kinase 22.7.11.220.461
1fvv107Cyclin-dependent kinase 22.7.11.220.459
3qqkX02Cyclin-dependent kinase 22.7.11.220.458
3qzhX69Cyclin-dependent kinase 22.7.11.220.458
2r3p3SCCyclin-dependent kinase 22.7.11.220.457
3rmf20ZCyclin-dependent kinase 22.7.11.220.457
4fkr45KCyclin-dependent kinase 22.7.11.220.457
1e1xNW1Cyclin-dependent kinase 22.7.11.220.456
1h0w207Cyclin-dependent kinase 22.7.11.220.456
3rk507ZCyclin-dependent kinase 22.7.11.220.456
4erwSTUCyclin-dependent kinase 22.7.11.220.456
3qxpX64Cyclin-dependent kinase 22.7.11.220.455
1b39ATPCyclin-dependent kinase 22.7.11.220.454
1h1s4SPCyclin-dependent kinase 22.7.11.220.454
3qtzX42Cyclin-dependent kinase 22.7.11.220.454
3unk0BYCyclin-dependent kinase 22.7.11.220.454
3lfsA07Cyclin-dependent kinase 22.7.11.220.453
3rpy27ZCyclin-dependent kinase 22.7.11.220.453
3sw719KCyclin-dependent kinase 22.7.11.220.453
2vtsLZCCyclin-dependent kinase 22.7.11.220.452
4fko20KCyclin-dependent kinase 22.7.11.220.452
1vyzN5BCyclin-dependent kinase 22.7.11.220.451
2bheBRYCyclin-dependent kinase 22.7.11.220.451
3r73X87Cyclin-dependent kinase 22.7.11.220.451
2c69CT8Cyclin-dependent kinase 22.7.11.220.449
2c6lDT4Cyclin-dependent kinase 22.7.11.220.449
3qqhX0ACyclin-dependent kinase 22.7.11.220.449
2c6iDT1Cyclin-dependent kinase 22.7.11.220.448
2duv371Cyclin-dependent kinase 22.7.11.220.448
4lyn1YGCyclin-dependent kinase 22.7.11.220.448
3py0SU9Cyclin-dependent kinase 22.7.11.220.447
3qqfX07Cyclin-dependent kinase 22.7.11.220.447
3rahO1ZCyclin-dependent kinase 22.7.11.220.447
1h1r6CPCyclin-dependent kinase 22.7.11.220.444
3r9hZ67Cyclin-dependent kinase 22.7.11.220.444
1oguST8Cyclin-dependent kinase 22.7.11.220.443
1pxpCK8Cyclin-dependent kinase 22.7.11.220.443
1r78FMDCyclin-dependent kinase 22.7.11.220.441
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.441
3ig7EFPCyclin-dependent kinase 22.7.11.220.441
3qtrX36Cyclin-dependent kinase 22.7.11.220.441
4fkw62KCyclin-dependent kinase 22.7.11.220.440