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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1jszNDMCap-specific mRNA (nucleoside-2'-O-)-methyltransferase2.1.1.57

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1jszNDMCap-specific mRNA (nucleoside-2'-O-)-methyltransferase2.1.1.571.000
1eqaMG7Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase2.1.1.570.769
1nj6A5AProline--tRNA ligase/0.509
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.507
4nceMGTPolymerase basic protein 2/0.504
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.503
1nj5P5AProline--tRNA ligase/0.497
2gfxPMN3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.495
1qh0FADFerredoxin--NADP reductase1.18.1.20.494
4c717RD3-oxoacyl-ACP synthase/0.494
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.493
2pucGUNHTH-type transcriptional repressor PurR/0.492
3h3qH13Collagen type IV alpha-3-binding protein/0.492
4daj0HKMuscarinic acetylcholine receptor M3/0.491
1n2sNAIdTDP-4-dehydrorhamnose reductase1.1.1.1330.490
2xnvVU3Soluble acetylcholine receptor/0.489
4gg1TZDBenzoylformate decarboxylase4.1.1.70.489
4ise1FWGlucokinase2.7.1.20.489
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.488
4dlcUMPDeoxyuridine triphosphatase, putative/0.488
4isg1FYGlucokinase2.7.1.20.488
2p99YE6Methionine aminopeptidase/0.487
3fsjD7KBenzoylformate decarboxylase4.1.1.70.487
1giqNAIIota toxin component Ia/0.486
2ckmAA7Acetylcholinesterase3.1.1.70.486
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.486
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.486
2vqzMGTPolymerase basic protein 2/0.485
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.485
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.484
2vi5Y196,7-dimethyl-8-ribityllumazine synthase2.5.1.780.484
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.483
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.482
1odcA8BAcetylcholinesterase3.1.1.70.482
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.482
2evcFC3Methionine aminopeptidase/0.482
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.481
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.481
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.480
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.479
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.478
1queFADFerredoxin--NADP reductase1.18.1.20.478
3zv7NHGAcetylcholinesterase3.1.1.70.478
1gky5GPGuanylate kinase2.7.4.80.477
2w6cBM4Acetylcholinesterase3.1.1.70.477
2xupTZ5Acetylcholinesterase3.1.1.70.477
3h3r14HCollagen type IV alpha-3-binding protein/0.477
1rkwPNTHTH-type transcriptional regulator QacR/0.476
2gs9SAHUncharacterized protein/0.475
3biz61EWee1-like protein kinase2.7.10.20.475
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.475
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.475
5ero210Fusicoccadiene synthase2.5.1.290.475
1gjrFADFerredoxin--NADP reductase1.18.1.20.474
1jdzFMBPurine nucleoside phosphorylase/0.474
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.474
2bd0BIOSepiapterin reductase/0.474
2w6qOA5Biotin carboxylase6.3.4.140.474
3zc3FADFerredoxin--NADP reductase1.18.1.20.474
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2aqbTL63-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.473
2cekN8TAcetylcholinesterase3.1.1.70.473
3zg6APRNAD-dependent protein deacetylase sirtuin-63.5.10.473
4bprFADFerredoxin--NADP reductase1.18.1.20.473
4j3mAJ8Tankyrase-22.4.2.300.473
4xt8TMQPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.473
1o2g696Prothrombin3.4.21.50.472
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.472
1ut6A8NAcetylcholinesterase3.1.1.70.472
3voiRCBGlucanase/0.472
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.472
1nm6L86Prothrombin3.4.21.50.471
1w6jR71Lanosterol synthase5.4.99.70.471
2a2dANPN-acetylgalactosamine kinase2.7.1.1570.471
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.471
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.471
3t4hMD5Alpha-ketoglutarate-dependent dioxygenase AlkB1.14.11.330.471
1o2eANNPhospholipase A23.1.1.40.470
2clfF6FTryptophan synthase alpha chain/0.470
3egkM18Prothrombin3.4.21.50.470
4a4xJUPSerine/threonine-protein kinase Nek22.7.11.10.470
4lrhFOLFolate receptor alpha/0.470
1gm8SOXPenicillin G acylase3.5.1.110.469
2a2xNA9Prothrombin3.4.21.50.469
2ejzSAHDiphthine synthase/0.469
2f2sCOAAcetyl-CoA acetyltransferase, mitochondrial2.3.1.90.469
2g1n1IGRenin3.4.23.150.469
2whqHI6Acetylcholinesterase3.1.1.70.469
3v2uATPProtein GAL3/0.469
4c6zTLE3-oxoacyl-ACP synthase/0.469
4jv3N32Beta-ketoacyl synthase/0.469
5a4wQCTGlutathione S-transferase F22.5.1.180.469
1yqzCOACoenzyme A disulfide reductase/0.468
2q94A04Methionine aminopeptidase/0.468
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.468
3fhxPLPPyridoxal kinase2.7.1.350.468
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.468
4u163C0Muscarinic acetylcholine receptor M3/0.468
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.467
4cb4MGTPolymerase basic protein 2/0.467
4mprTPPBenzoylformate decarboxylase4.1.1.70.467
4n9qFMNFMN-dependent NADH-azoreductase 1/0.467
1dx6GNTAcetylcholinesterase3.1.1.70.466
1itzTPPTransketolase, chloroplastic2.2.1.10.466
1u65CP0Acetylcholinesterase3.1.1.70.466
2j2pSC2Ficolin-2/0.466
2wqpWQPPolysialic acid capsule biosynthesis protein SiaC/0.466
2wzgUPGUncharacterized protein/0.466
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3vf60H6Glucokinase2.7.1.20.466
4to5DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.466
1dggNDPCatalase1.11.1.60.465
1wm1PTBProline iminopeptidase3.4.11.50.465
1zgbA1EAcetylcholinesterase3.1.1.70.465
2futH1SHeparin and heparin-sulfate lyase/0.465
3zhoFMNNAD(P)H dehydrogenase (quinone)/0.465
1umcTDP2-oxoisovalerate dehydrogenase subunit alpha1.2.4.40.464
1umcTDP2-oxoisovalerate dehydrogenase subunit beta1.2.4.40.464
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.464
3pkeY10Methionine aminopeptidase 2/0.464
4yao2AMNADPH--cytochrome P450 reductase/0.464
1gj5130Prothrombin3.4.21.50.463
1h85FADFerredoxin--NADP reductase1.18.1.20.463
2ociTYCValacyclovir hydrolase3.10.463
3dhk23UProthrombin3.4.21.50.463
3ho9N3A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.463
3r7mSUZAldo-keto reductase family 1 member C3/0.463
4drn0MCPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.463
4gm4TZDBenzoylformate decarboxylase4.1.1.70.463
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.462
1rpwDIDHTH-type transcriptional regulator QacR/0.462
2evmFC2Methionine aminopeptidase/0.462
2q92B23Methionine aminopeptidase/0.462
2vb8TLM3-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.462
2xi4AFTAcetylcholinesterase3.1.1.70.462
2y1x845Histone-arginine methyltransferase CARM1/0.462
3lzwNAPFerredoxin--NADP reductase 21.18.1.20.462
3ox279XRibosyldihydronicotinamide dehydrogenase [quinone]/0.462
1pq944BOxysterols receptor LXR-beta/0.461
1rxjBNIStreptavidin/0.461
1zgcA2EAcetylcholinesterase3.1.1.70.461
2po3T4K4-dehydrase/0.461
2xujTZ5Acetylcholinesterase3.1.1.70.461
2zhe13UProthrombin3.4.21.50.461
3c0zSHHHistone deacetylase 73.5.1.980.461
3hxcBD6Geranylgeranyl transferase type-2 subunit beta2.5.1.600.461
4da7AC2Purine nucleoside phosphorylase DeoD-type2.4.2.10.461
4fa30SLAldo-keto reductase family 1 member C3/0.461
4j7hTRHPCZA361.3/0.461
4jq4IMNAldo-keto reductase family 1 member C2/0.461
4n4v2GYTankyrase-12.4.2.300.461
4relKMPGlycosyltransferase/0.461
5cxv0HKMuscarinic acetylcholine receptor M1/0.461
1c4vIH2Prothrombin3.4.21.50.460
1d3pBT3Prothrombin3.4.21.50.460
1dghNDPCatalase1.11.1.60.460
1ktsC24Prothrombin3.4.21.50.460
2uxoTACHTH-type transcriptional regulator TtgR/0.460
2xf3J01Uncharacterized protein/0.460
3br3ETHTH-type transcriptional regulator QacR/0.460
3gxfIFMGlucosylceramidase3.2.1.450.460
3nh8DC2N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming)3.5.1.1140.460
3slkNDPPolyketide synthase extender module 2/0.460
4bfwZVWPantothenate kinase2.7.1.330.460
4da8BG2Purine nucleoside phosphorylase DeoD-type2.4.2.10.460
4dbs0HVAldo-keto reductase family 1 member C3/0.460
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
5ewkP34Putative secreted protein/0.460
1dp2LPBThiosulfate sulfurtransferase/0.459
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.459
1jwtBLIProthrombin3.4.21.50.459
1lpcCMPAntiviral protein DAP-303.2.2.220.459
1po7TZDBenzoylformate decarboxylase4.1.1.70.459
1sm4FADFerredoxin--NADP reductase/0.459
2ed3SAHDiphthine synthase/0.459
2rqfJH3Hemolymph juvenile hormone binding protein/0.459
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.459
3d4bDZDNAD-dependent protein deacetylase/0.459
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
3i8p8403-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.459
3iogSDFMetallo-beta-lactamase type 2/0.459
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
4eqsCOACoenzyme A disulfide reductase/0.459
1fndFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.458
1ry0PG2Aldo-keto reductase family 1 member C3/0.458
1swgBTNStreptavidin/0.458
1toiHCIAspartate aminotransferase2.6.1.10.458
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.458
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.458
2zs8ADPPantothenate kinase2.7.1.330.458
3bxoUPPdTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose/0.458
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3zhqTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.458
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.458
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.458
4b68NAPL-ornithine N(5)-monooxygenase/0.458
8catNDPCatalase1.11.1.60.458
1qtiGNTAcetylcholinesterase3.1.1.70.457
1sb1165Prothrombin3.4.21.50.457
2xuoTZ4Acetylcholinesterase3.1.1.70.457
3c3eFO12-phospho-L-lactate transferase/0.457
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3nfrEWQRibosyldihydronicotinamide dehydrogenase [quinone]/0.457
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.457
4eqrCOACoenzyme A disulfide reductase/0.457
4jeyPLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.457
4z87GDPInosine-5'-monophosphate dehydrogenase/0.457
1z6tADPApoptotic protease-activating factor 1/0.456
2j3qTFLAcetylcholinesterase3.1.1.70.456
2jf0HBPAcetylcholinesterase3.1.1.70.456
2ok8FADFerredoxin--NADP reductase, apicoplast/0.456
2p98YE7Methionine aminopeptidase/0.456
2xlpNAPPutative flavin-containing monooxygenase/0.456
3g11P9C3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.456
3ho2N323-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.456
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.456
1h22E10Acetylcholinesterase3.1.1.70.455
1v93FADMethylenetetrahydrofolate reductase/0.455
1votHUPAcetylcholinesterase3.1.1.70.455
2aouCQAHistamine N-methyltransferase2.1.1.80.455
2bzsCB1Ribosyldihydronicotinamide dehydrogenase [quinone]/0.455
2cn0F25Prothrombin3.4.21.50.455
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.455
3bldPRFQueuine tRNA-ribosyltransferase2.4.2.290.455
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.455
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.455
4r81FMNPredicted NADH dehydrogenase/0.455
4wx2F6FTryptophan synthase alpha chain/0.455
4wx2F6FTryptophan synthase beta chain4.2.1.200.455
1e63FADFerredoxin--NADP reductase1.18.1.20.454
1lnmDTXBilin-binding protein/0.454
1qgzFADFerredoxin--NADP reductase1.18.1.20.454
1y6oMJIPhospholipase A2, major isoenzyme3.1.1.40.454
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.454
2pncCLUPrimary amine oxidase, liver isozyme/0.454
3dz6M8ES-adenosylmethionine decarboxylase proenzyme4.1.1.500.454
3iktNADRedox-sensing transcriptional repressor Rex/0.454
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.454
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.454
3rqwACHGamma-aminobutyric-acid receptor subunit beta-1/0.454
4cdmFO1Deoxyribodipyrimidine photolyase/0.454
4eqwCOACoenzyme A disulfide reductase/0.454
4es5MGTPolymerase basic protein 2/0.454
4rtbSAMPutative thiazole biosynthesis protein ThiH/0.454
2ycxP32Beta-1 adrenergic receptor/0.454
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.453
2wzmNA7Uncharacterized oxidoreductase MSMEG_2407/MSMEI_2346/0.453
2wzySQXSoluble acetylcholine receptor/0.453
3af1GDPPantothenate kinase2.7.1.330.453
3rsv3RSBeta-secretase 13.4.23.460.453
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.453
3u8fFGMRibosome inactivating protein/0.453
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.453
4kbyC2EStimulator of interferon genes protein/0.453
3pblETQD(3) dopamine receptor/0.453
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.452
1eveE20Acetylcholinesterase3.1.1.70.452
1kw0H4BPhenylalanine-4-hydroxylase1.14.16.10.452
1sdwIYTPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.452
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.452
1w4lGL8Acetylcholinesterase3.1.1.70.452
1z71L17Prothrombin3.4.21.50.452
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.452
2gg8U15Methionine aminopeptidase/0.452
2xdaJPS3-dehydroquinate dehydratase4.2.1.100.452
2xncFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.452
2xugTZ4Acetylcholinesterase3.1.1.70.452
3anlSYC1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.452
3dd0EZLCarbonic anhydrase 24.2.1.10.452
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.452
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.452
3fr5I4AFatty acid-binding protein, adipocyte/0.452
3hxfBD9Geranylgeranyl transferase type-2 subunit beta2.5.1.600.452
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.452
3q43D66M1 family aminopeptidase3.4.110.452
3wtkTH4Acetylcholine-binding protein/0.452
4cb741GPolymerase basic protein 2/0.452
4fam0SZAldo-keto reductase family 1 member C3/0.452
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.452
4n1gCEIObelin/0.452
1bx0FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.451
1ej3CZHAequorin-2/0.451
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.451
1ftlDNQGlutamate receptor 2/0.451
1fvpFMANon-fluorescent flavoprotein/0.451
1fwyUD1Bifunctional protein GlmU/0.451
1jqdSAHHistamine N-methyltransferase2.1.1.80.451
1m9jCLWNitric oxide synthase, endothelial1.14.13.390.451
1qvuPRLHTH-type transcriptional regulator QacR/0.451
1x1bSAHC-20 methyltransferase/0.451
1xr2C2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase2.1.1.140.451
2flhZEACytokinin-specific binding protein/0.451
2ok7A2PFerredoxin--NADP reductase, apicoplast/0.451
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
3kej3EJCollagenase 33.4.240.451
4bfuZVUPantothenate kinase2.7.1.330.451
4mv4ACPBiotin carboxylase6.3.4.140.451
4uy6SAHHistidine N-alpha-methyltransferase/0.451
1b2rFADFerredoxin--NADP reductase1.18.1.20.450
1g6kNADGlucose 1-dehydrogenase1.1.1.470.450
1o9bNAIQuinate/shikimate dehydrogenase/0.450
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.450
1vi2NADQuinate/shikimate dehydrogenase/0.450
1yw8A75Methionine aminopeptidase 2/0.450
2b8jADNClass B acid phosphatase3.1.3.20.450
2ggbU17Methionine aminopeptidase/0.450
2glrGTXGlutathione S-transferase P 12.5.1.180.450
2hr8SAHDiphthine synthase/0.450
2xuhTZ4Acetylcholinesterase3.1.1.70.450
3c1oNAPEugenol synthase/0.450
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.450
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.450
4c43FADFerredoxin--NADP reductase1.18.1.20.450
4e32DWNMethyltransferase/0.450
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.450
4j0t6T9Beta-secretase 13.4.23.460.450
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.450
5c4nNAPPrecorrin-6A reductase1.3.1.540.450
5fd8A5APutative carboxypeptidase yocD/0.450
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.449
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.449
1x8lOXRRetinol dehydratase/0.449
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
2c4iBTNAvidin/0.449
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.449
2gyuHI6Acetylcholinesterase3.1.1.70.449
3c1kT15Prothrombin3.4.21.50.449
3f8sPF2Dipeptidyl peptidase 4/0.449
3gncQQQGlutaryl-CoA dehydrogenase/0.449
3iu9T07Methionine aminopeptidase 2/0.449
3juoAJDPhenazine biosynthesis protein A/B/0.449
3pftFMNFlavin reductase/0.449
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.449
4bfvZVVPantothenate kinase2.7.1.330.449
4bfzZVZPantothenate kinase2.7.1.330.449
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.449
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.449
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.449
4o9cCOAAcetyl-CoA acetyltransferase2.3.1.90.449
4qtnNNRNicotinamide riboside transporter PnuC/0.449
5stdUNNScytalone dehydratase4.2.1.940.449
6gsuGPSGlutathione S-transferase Mu 12.5.1.180.449
1e66HUXAcetylcholinesterase3.1.1.70.448
1ja0FADNADPH--cytochrome P450 reductase/0.448
1r58AO5Methionine aminopeptidase 2/0.448
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.448
1w6rGNTAcetylcholinesterase3.1.1.70.448
1xp8AGSProtein RecA/0.448
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.448
2gg2U12Methionine aminopeptidase/0.448
2hxzH7JCathepsin S3.4.22.270.448
2zrzFNRIsopentenyl-diphosphate delta-isomerase/0.448
3pkbY16Methionine aminopeptidase 2/0.448
3rthRTHBeta-secretase 13.4.23.460.448
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.448
4arbC57Acetylcholinesterase3.1.1.70.448
4b67FADL-ornithine N(5)-monooxygenase/0.448
4b6s2HN3-dehydroquinate dehydratase4.2.1.100.448
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.448
4ey6GNTAcetylcholinesterase3.1.1.70.448
4g090VDHistidinol dehydrogenase/0.448
5dsg0HKMuscarinic acetylcholine receptor M4/0.448
3ny9JSZBeta-2 adrenergic receptor/0.448
1d3dBZTProthrombin3.4.21.50.447
1go2FADFerredoxin--NADP reductase1.18.1.20.447
1nceCB3Thymidylate synthase/0.447
1o5rFR9Adenosine deaminase3.5.4.40.447
1oycFMNNADPH dehydrogenase 11.6.99.10.447
1xvtCOAL-carnitine CoA-transferase/0.447
2rc6FADFerredoxin--NADP reductase/0.447
2x86ADPADP-L-glycero-D-manno-heptose-6-epimerase/0.447
3bi6396Wee1-like protein kinase2.7.10.20.447
3ce0P34Poly [ADP-ribose] polymerase 32.4.2.300.447
3fazNOSPurine nucleoside phosphorylase/0.447
3hk1B64Fatty acid-binding protein, adipocyte/0.447
3jszUPGUncharacterized protein/0.447
4bz8J38Histone deacetylase/0.447
4dch4DCGlucokinase2.7.1.20.447
4fhd0TTSpore photoproduct lyase/0.447
4fl0PLPAminotransferase ALD1, chloroplastic2.6.10.447
4jqaID8Aldo-keto reductase family 1 member C2/0.447
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.447
4rh10TTSpore photoproduct lyase/0.447
5ilwURIRibosome inactivating protein/0.447
1e2lTMCThymidine kinase/0.446
1hi0GTPRNA-directed RNA polymerase2.7.7.480.446
1rszDIHPurine nucleoside phosphorylase2.4.2.10.446
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.446
2bdyUNBProthrombin3.4.21.50.446
2g1m4HGEgl nine homolog 1/0.446
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.446
2yac937Serine/threonine-protein kinase PLK12.7.11.210.446
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3fpkFADFerredoxin-NADP reductase/0.446
3h3t16HCollagen type IV alpha-3-binding protein/0.446
3pm1ETHTH-type transcriptional regulator QacR/0.446
4bfyZVYPantothenate kinase2.7.1.330.446
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.446
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4qfyDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.446
1amoFADNADPH--cytochrome P450 reductase/0.445
1bl4AP1Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.445
1dr4HBIDihydrofolate reductase1.5.1.30.445
1qtqQSIGlutamine--tRNA ligase6.1.1.180.445
1r5hAO2Methionine aminopeptidase 2/0.445
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.445
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.445
2gbyBRNHTH-type transcriptional regulator QacR/0.445
2iu8UD1UDP-3-O-acylglucosamine N-acyltransferase2.3.10.445
2pb1NFGGlucan 1,3-beta-glucosidase/0.445
2pitDHTAndrogen receptor/0.445
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.445
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.445
2tplHPPTyrosine phenol-lyase4.1.99.20.445
2zc922UProthrombin3.4.21.50.445
3b8hNADExotoxin A2.4.2.360.445
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.445
3er93ATPoly(A) polymerase catalytic subunit2.7.7.190.445
3kmyD8YBeta-secretase 13.4.23.460.445
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.445
3wqmB29Diterpene synthase3.1.7.80.445
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.445
4l8u9AZSerum albumin/0.445
4m0f1YKAcetylcholinesterase3.1.1.70.445
1afeALZProthrombin3.4.21.50.444
1f4gTP4Thymidylate synthase/0.444
1hqtNAPAlcohol dehydrogenase [NADP(+)]1.1.1.20.444
1s7gNADNAD-dependent protein deacylase 2/0.444
1xm1GAHProthrombin3.4.21.50.444
1yplRA8Prothrombin3.4.21.50.444
2cleF6FTryptophan synthase alpha chain/0.444
2cmfF11Acetylcholinesterase3.1.1.70.444
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.444
2gywOBIAcetylcholinesterase3.1.1.70.444
2nq7HM5Methionine aminopeptidase 1/0.444
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.444
2oacGTBGlutathione S-transferase P 12.5.1.180.444
2rd2QSIGlutamine--tRNA ligase6.1.1.180.444
2rd678PPoly [ADP-ribose] polymerase 12.4.2.300.444
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.444
2zitNADExotoxin A2.4.2.360.444
3dz7O8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.444
3ha5SFGHydroxymycolate synthase MmaA42.1.10.444
3hggCHDCmeR/0.444
3hl0NADMaleylacetate reductase/0.444
3pkaY02Methionine aminopeptidase 2/0.444
3r6iJMSAldo-keto reductase family 1 member C3/0.444
3r94FLRAldo-keto reductase family 1 member C3/0.444
3zj6VM2Raucaffricine-O-beta-D-glucosidase3.2.1.1250.444
4cb629RPolymerase basic protein 2/0.444
4dk70KSOxysterols receptor LXR-beta/0.444
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4fwjFADLysine-specific histone demethylase 1B10.444
4lngJANCaaX farnesyltransferase beta subunit Ram1/0.444
4n3l2FNProthrombin3.4.21.50.444
5ao1DG3Deoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.444
5epeSAHUncharacterized protein/0.444
5f59SAHHistone-lysine N-methyltransferase 2C2.1.1.430.444
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.443
1fkbRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.443
1gulGLY_GGL_ICYGlutathione S-transferase A42.5.1.180.443
1n8wCOAMalate synthase G/0.443
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.443
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.443
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.443
2gg0U11Methionine aminopeptidase/0.443
2ha6SCKAcetylcholinesterase3.1.1.70.443
2jl1NAPTriphenylmethane reductase/0.443
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
2xuqTZ4Acetylcholinesterase3.1.1.70.443
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.443
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.443
3p2oNADBifunctional protein FolD/0.443
3pkcY08Methionine aminopeptidase 2/0.443
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.443
4b5nFMNNAD(P)H:flavin oxidoreductase Sye4/0.443
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.300.443
5erm210Fusicoccadiene synthase4.2.3.430.443
1qy2IPZMajor urinary protein 1/0.442
1swpBTNStreptavidin/0.442
1t4u81AProthrombin3.4.21.50.442
1w76GNTAcetylcholinesterase3.1.1.70.442
2aovC2MHistamine N-methyltransferase2.1.1.80.442
2oliIOPBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.442
2vuuNAPNitrogen metabolite repression protein nmrA/0.442
2xq0BESLeukotriene A-4 hydrolase homolog3.3.2.60.442
3aosJH2Hemolymph juvenile hormone binding protein/0.442
3e4aQIXInsulin-degrading enzyme3.4.24.560.442
3lzzGDPUncharacterized protein/0.442
3pdqKC6Lysine-specific demethylase 4A1.14.110.442
3rykTYDdTDP-4-dehydrorhamnose 3,5-epimerase/0.442
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.442
3up3XCAaceDAF-12/0.442
3uptTPPTransketolase/0.442
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.442
4gv7MEWPoly [ADP-ribose] polymerase 12.4.2.300.442
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.442
4nvk2NYPeroxidase/0.442
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.442
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.442
5d6lCAUBeta-2 adrenergic receptor/0.442
1h60STRPentaerythritol tetranitrate reductase/0.441
1ihiIU5Aldo-keto reductase family 1 member C2/0.441
1kziTHGThymidylate synthase/0.441
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
1mrqSTRAldo-keto reductase family 1 member C1/0.441
1n5vNOMActVA 6 protein/0.441
1p33MTXPteridine reductase 11.5.1.330.441
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.441
2ga2A19Methionine aminopeptidase 2/0.441
2vyxFMNDodecin/0.441
3iu7FCDMethionine aminopeptidase 2/0.441
3kek3EKCollagenase 33.4.240.441
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.441
4b7zQ4QAcetylcholinesterase3.1.1.70.441
4d6qPD2Lysine-specific demethylase 4D1.14.110.441
4jq3ZOMAldo-keto reductase family 1 member C2/0.441
4n3r2GUTankyrase-12.4.2.300.441
1ay0TPPTransketolase 12.2.1.10.440
1c23MPHMethionine aminopeptidase/0.440
1c7oPPGHemolysin/0.440
1ogiFADFerredoxin--NADP reductase1.18.1.20.440
1oytFSNProthrombin3.4.21.50.440
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.440
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2a4xBLMMitomycin-binding protein/0.440
2e0nSAHPrecorrin-2 C20-methyltransferase/0.440
2ow9SP6Collagenase 33.4.240.440
2xnpWCXSerine/threonine-protein kinase Nek22.7.11.10.440
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.440
2zhq27UProthrombin3.4.21.50.440
3dzjNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.440
3h1vTK1Glucokinase2.7.1.20.440
3juqAJDPhenazine biosynthesis protein A/B/0.440
3s5wFADL-ornithine N(5)-monooxygenase/0.440
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
3w5uFADFerredoxin/0.440
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.440
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4b4w9L9Bifunctional protein FolD/0.440
4c2pX8ZAngiotensin-converting enzyme3.2.10.440
4jtqFLPAldo-keto reductase family 1 member C2/0.440
4tjy3GNTankyrase-22.4.2.300.440