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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1iv4C5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.12

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1iv4C5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.121.000
1iv2CDP2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.539
4c8eC5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.501
3iewCTP2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.498
3k145352-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.495
3f0gC5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.491
3jvhHHV2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.478
1h47C5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.476
1h48C5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.469
3elcF012-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.460
1gx1CDP2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.458
3t80CTN2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.455
2amt1AA2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.451
1h48CDI2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.450
3p0zCTN2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.446
3k2xI5A2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.441