sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1it7	GUN	tRNA-guanine(15) transglycosylase	2.4.2.48

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1it7	GUN	tRNA-guanine(15) transglycosylase	2.4.2.48	1.000
4fps	0UX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.484
4gi4	0EX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.474
1p0e	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.465
3vg9	ZMA	Adenosine receptor A2a	/	0.459
4l17	DNQ	Glutamate receptor 2	/	0.458
2bil	BI1	Serine/threonine-protein kinase pim-1	2.7.11.1	0.456
4jib	1L6	cGMP-dependent 3',5'-cyclic phosphodiesterase	3.1.4.17	0.453
3njo	PYV	Abscisic acid receptor PYR1	/	0.452
4mmf	29Q	Na(+):neurotransmitter symporter (Snf family)	/	0.447
4gkt	0O1	Queuine tRNA-ribosyltransferase	2.4.2.29	0.442
2zu9	GDP	Mannosyl-3-phosphoglycerate synthase	2.4.1.217	0.441