Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ieiZESAldose reductase1.1.1.21

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1ieiZESAldose reductase1.1.1.211.000
2fz8ZSTAldose reductase1.1.1.210.583
2pdu393Aldose reductase1.1.1.210.578
3mb9ZSTAldose reductase1.1.1.210.566
2pdxZSTAldose reductase1.1.1.210.561
2fz9ZSTAldose reductase1.1.1.210.540
2hv5ZSTAldose reductase1.1.1.210.531
2pdg47DAldose reductase1.1.1.210.529
2dv0ZSTAldose reductase1.1.1.210.528
2iqdLPAAldose reductase1.1.1.210.511
2pdp393Aldose reductase1.1.1.210.508
1z8962PAldose reductase1.1.1.210.497
2i16LDTAldose reductase1.1.1.210.496
3ld5LDTAldose reductase1.1.1.210.495
2pdyFIDAldose reductase1.1.1.210.493
3ghrLDTAldose reductase1.1.1.210.493
1z3n3NAAldose reductase1.1.1.210.491
3ghsLDTAldose reductase1.1.1.210.490
2iki388Aldose reductase1.1.1.210.487
3m64393Aldose reductase1.1.1.210.486
4gca2X9Aldose reductase1.1.1.210.482
2qxwLDTAldose reductase1.1.1.210.481
1t40ID5Aldose reductase1.1.1.210.478
2pdc393Aldose reductase1.1.1.210.478
3lboLDTAldose reductase1.1.1.210.477
2pdj393Aldose reductase1.1.1.210.475
3lqlLDTAldose reductase1.1.1.210.475
2f2kTGGAldose reductase1.1.1.210.469
3ghtLDTAldose reductase1.1.1.210.466
1pwlBFIAldose reductase1.1.1.210.465
2ikj393Aldose reductase1.1.1.210.465
1t41ID5Aldose reductase1.1.1.210.464
3lz5LDTAldose reductase1.1.1.210.462
3m0iZSTAldose reductase1.1.1.210.462
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.462
4yfy0FXVioF/0.462
2pzn393Aldose reductase1.1.1.210.460
3lenZSTAldose reductase1.1.1.210.460
2aot2PMHistamine N-methyltransferase2.1.1.80.458
3g5eQ74Aldose reductase1.1.1.210.458
2hvoZSTAldose reductase1.1.1.210.457
3m4h388Aldose reductase1.1.1.210.457
3mc5393Aldose reductase1.1.1.210.457
2duzZSTAldose reductase1.1.1.210.452
2pdq47DAldose reductase1.1.1.210.452
2duxZSTAldose reductase1.1.1.210.449
2xuiTZ5Acetylcholinesterase3.1.1.70.449
1us0LDTAldose reductase1.1.1.210.447
2pdn47DAldose reductase1.1.1.210.447
3casASD3-oxo-5-beta-steroid 4-dehydrogenase/0.447
1ry8RUTAldo-keto reductase family 1 member C3/0.446
1q84TZ4Acetylcholinesterase3.1.1.70.445
5ctoNTD4-hydroxyphenylpyruvate dioxygenase1.13.11.270.443
2dhfDZFDihydrofolate reductase1.5.1.30.442
2i17LDTAldose reductase1.1.1.210.442
2xuqTZ4Acetylcholinesterase3.1.1.70.441
4j7hTRHPCZA361.3/0.441
1q23FUAChloramphenicol acetyltransferase2.3.1.280.440
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.440
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.440
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.440
4yu153NAldose reductase1.1.1.210.440