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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ht834CProstaglandin G/H synthase 11.14.99.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1ht834CProstaglandin G/H synthase 11.14.99.11.000
1eqhFLPProstaglandin G/H synthase 11.14.99.10.627
2aylFLPProstaglandin G/H synthase 11.14.99.10.617
1eqgIBPProstaglandin G/H synthase 11.14.99.10.608
1q4gBFLProstaglandin G/H synthase 11.14.99.10.580
3n8wFLPProstaglandin G/H synthase 11.14.99.10.578
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.563
3n8zFLPProstaglandin G/H synthase 11.14.99.10.560
4fm5DF0Prostaglandin G/H synthase 21.14.99.10.544
3n8xNIMProstaglandin G/H synthase 11.14.99.10.540
4ph9IBPProstaglandin G/H synthase 21.14.99.10.518
3rr3FLRProstaglandin G/H synthase 21.14.99.10.506
3n8yDIFProstaglandin G/H synthase 11.14.99.10.505
3ntgD72Prostaglandin G/H synthase 21.14.99.10.504
3pghFLPProstaglandin G/H synthase 21.14.99.10.499
4coxIMNProstaglandin G/H synthase 21.14.99.10.489
3q7dNPXProstaglandin G/H synthase 21.14.99.10.471
5ikrID8Prostaglandin G/H synthase 21.14.99.10.471
3mqe416Prostaglandin G/H synthase 21.14.99.10.453