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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1ht5FL2Prostaglandin G/H synthase 11.14.99.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1ht5FL2Prostaglandin G/H synthase 11.14.99.11.000
5ikqJMSProstaglandin G/H synthase 21.14.99.10.586
3kk6CELProstaglandin G/H synthase 11.14.99.10.496
1pxxDIFProstaglandin G/H synthase 21.14.99.10.495
2oyuIMSProstaglandin G/H synthase 11.14.99.10.472
4rrwLURProstaglandin G/H synthase 21.14.99.10.466
4rrzLURProstaglandin G/H synthase 21.14.99.10.466
6coxS58Prostaglandin G/H synthase 21.14.99.10.449
3oqkS52Renin3.4.23.150.440