sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1gwn | GTP | Rho-related GTP-binding protein RhoE |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 1.000 | |
| 1m7b | GTP | Rho-related GTP-binding protein RhoE | / | 0.628 | |
| 2cls | GTP | Rho-related GTP-binding protein Rho6 | / | 0.511 | |
| 4gzm | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.496 | |
| 2fju | GSP | Ras-related C3 botulinum toxin substrate 1 | / | 0.490 | |
| 3oiv | GNP | GTPase HRas | / | 0.482 | |
| 1cxz | GSP | Transforming protein RhoA | / | 0.480 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.479 | |
| 1zc3 | GNP | Ras-related protein Ral-A | / | 0.477 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.476 | |
| 2gcp | GSP | Rho-related GTP-binding protein RhoC | / | 0.469 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.466 | |
| 1zc4 | GNP | Ras-related protein Ral-A | / | 0.461 | |
| 3kuc | GDP | Ras-related protein Rap-1A | / | 0.459 | |
| 1xts | GTP | GTP-binding protein Rheb | / | 0.458 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.458 | |
| 4js0 | GNP | Cell division control protein 42 homolog | / | 0.450 | |
| 3kz1 | GSP | Transforming protein RhoA | / | 0.449 | |
| 1a2b | GSP | Transforming protein RhoA | / | 0.448 | |
| 4cym | GCP | Ras-related protein Rab-32 | / | 0.444 | |
| 2rge | GNP | GTPase HRas | / | 0.440 |