sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1gsn	FAD	Glutathione reductase, mitochondrial	1.8.1.7

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1gsn	FAD	Glutathione reductase, mitochondrial	1.8.1.7	1.000
1k4q	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.697
1grg	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.636
1gre	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.597
3grs	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.594
1grh	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.593
4gr1	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.590
1gra	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.586
1bwc	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.567
3dk9	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.524
3dk8	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.513
3dk4	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.511
3sqp	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.476
2gh5	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.446
3dgz	FAD	Thioredoxin reductase 2, mitochondrial	1.8.1.9	0.445
2nvk	FAD	Thioredoxin reductase 1, mitochondrial	1.8.1.9	0.444