sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1gre	FAD	Glutathione reductase, mitochondrial	1.8.1.7

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1gre	FAD	Glutathione reductase, mitochondrial	1.8.1.7	1.000
1grg	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.900
1grh	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.887
4gr1	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.848
3grs	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.827
1gra	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.790
1grb	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.623
1k4q	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.588
1gsn	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.586
1bwc	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.559
3dk9	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.540
3dk8	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.531
3dk4	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.514
3sqp	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.513
2gh5	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.461
3dgz	FAD	Thioredoxin reductase 2, mitochondrial	1.8.1.9	0.451