sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
1gra	FAD	Glutathione reductase, mitochondrial	1.8.1.7

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
1gra	FAD	Glutathione reductase, mitochondrial	1.8.1.7	1.000
1grg	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.872
1gre	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.819
3grs	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.796
1grh	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.793
4gr1	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.783
1gsn	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.598
1k4q	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.533
3dk8	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.530
3dk9	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.525
3dk4	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.524
1bwc	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.515
2gh5	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.470
3sqp	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.456