sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1giq | NAI | Iota toxin component Ia |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1giq | NAI | Iota toxin component Ia | / | 1.000 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.532 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.524 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.524 | |
| 2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.522 | |
| 2wn6 | NDP | ADP-ribosyltransferase enzymatic component | / | 0.520 | |
| 4ts9 | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.512 | |
| 4h0y | NAD | Iota toxin component Ia | / | 0.507 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.506 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.504 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.502 | |
| 3anl | SYC | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.500 | |
| 2ejz | SAH | Diphthine synthase | / | 0.498 | |
| 4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.498 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.498 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.496 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.496 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.492 | |
| 1qs2 | NAD | Vip2Ac | / | 0.491 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.491 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.490 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.489 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.489 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.489 | |
| 4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.489 | |
| 4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.489 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.487 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.486 | |
| 4b6l | 9ZP | Serine/threonine-protein kinase PLK3 | 2.7.11.21 | 0.486 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.486 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.485 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.484 | |
| 3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.484 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.483 | |
| 3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.483 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.483 | |
| 2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.482 | |
| 4f1y | CNI | Glutamate receptor 3 | / | 0.482 | |
| 1pxg | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.481 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.481 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.480 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.480 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.480 | |
| 1vzq | SHY | Prothrombin | 3.4.21.5 | 0.479 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.479 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.479 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.478 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.478 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.478 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.478 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.478 | |
| 1th6 | OIN | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.477 | |
| 3b7d | CNI | Glutamate receptor 2 | / | 0.477 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.476 | |
| 3jqc | JU2 | Pteridine reductase, putative | / | 0.476 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.476 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.475 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.475 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.475 | |
| 1c4y | IH3 | Prothrombin | 3.4.21.5 | 0.474 | |
| 1x2b | STX | Proline iminopeptidase | 3.4.11.5 | 0.474 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.474 | |
| 2nr4 | FMN | Conserved protein | / | 0.474 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.474 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.474 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.473 | |
| 3dhk | 23U | Prothrombin | 3.4.21.5 | 0.473 | |
| 2oth | NIM | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.472 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.472 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.472 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.472 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.471 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.471 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 3swc | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.471 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.471 | |
| 4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 1pr0 | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.470 | |
| 2clf | F6F | Tryptophan synthase alpha chain | / | 0.470 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.469 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.468 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.468 | |
| 3wqt | ANP | Cell division protein FtsA | / | 0.468 | |
| 4f3g | KAI | Glutamate receptor 3 | / | 0.468 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.467 | |
| 1k8z | IAG | Tryptophan synthase alpha chain | / | 0.467 | |
| 1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.467 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.467 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.467 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.467 | |
| 3lfz | ADP | Uncharacterized protein MJ1225 | / | 0.467 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.467 | |
| 1pke | 2FD | Purine nucleoside phosphorylase DeoD-type | / | 0.466 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.466 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.466 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.466 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.466 | |
| 3qtv | 06P | Prothrombin | 3.4.21.5 | 0.466 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.466 | |
| 1afe | ALZ | Prothrombin | 3.4.21.5 | 0.465 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.465 | |
| 1kts | C24 | Prothrombin | 3.4.21.5 | 0.465 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.465 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.465 | |
| 3anm | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.465 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.465 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.465 | |
| 1jsz | NDM | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase | 2.1.1.57 | 0.464 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.464 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.464 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.464 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.464 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.464 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.464 | |
| 4bgb | ADP | Predicted molecular chaperone distantly related to HSP70-fold metalloproteases | / | 0.464 | |
| 4isu | IKM | Glutamate receptor 2 | / | 0.464 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.463 | |
| 1t57 | FMN | Conserved protein | / | 0.463 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.463 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.463 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.463 | |
| 4afe | GGY | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.463 | |
| 4bz8 | J38 | Histone deacetylase | / | 0.463 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.462 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.462 | |
| 2poq | ISD | Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase | 1.3.1.20 | 0.462 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.462 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.462 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.462 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.462 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.462 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.461 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.461 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.461 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.461 | |
| 3zxh | E41 | Collagenase 3 | 3.4.24 | 0.461 | |
| 1asc | NPL | Aspartate aminotransferase | 2.6.1.1 | 0.460 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.460 | |
| 1rkw | PNT | HTH-type transcriptional regulator QacR | / | 0.460 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.460 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.460 | |
| 3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.460 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.460 | |
| 4bfd | 8T3 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.460 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.460 | |
| 1lv8 | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.459 | |
| 2qhx | FE1 | Pteridine reductase 1 | 1.5.1.33 | 0.459 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.459 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.459 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.458 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.458 | |
| 1mq0 | BRD | Cytidine deaminase | 3.5.4.5 | 0.458 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.458 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.458 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.458 | |
| 2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.458 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.458 | |
| 2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.458 | |
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.458 | |
| 4lwx | MU2 | Ribosome inactivating protein | / | 0.458 | |
| 1ae8 | AZL | Prothrombin | 3.4.21.5 | 0.457 | |
| 1e7w | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.457 | |
| 3jq8 | DX3 | Pteridine reductase, putative | / | 0.457 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.457 | |
| 4hmb | PZZ | Phospholipase A2 VRV-PL-VIIIa | / | 0.457 | |
| 4j1f | 1HL | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4l8v | NAP | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.457 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.457 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.457 | |
| 5dp2 | NAP | CurF | / | 0.457 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1kru | IPT | Galactoside O-acetyltransferase | 2.3.1.18 | 0.456 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.456 | |
| 1ozq | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.456 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.456 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.456 | |
| 3bld | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.456 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.456 | |
| 4bdr | KAI | Glutamate receptor ionotropic, kainate 2 | / | 0.456 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.456 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.455 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.455 | |
| 1pr5 | TBN | Purine nucleoside phosphorylase DeoD-type | / | 0.455 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.455 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.455 | |
| 2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.455 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.455 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.455 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.455 | |
| 4b5n | FMN | NAD(P)H:flavin oxidoreductase Sye4 | / | 0.455 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.455 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.455 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.455 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.454 | |
| 1x2e | ATX | Proline iminopeptidase | 3.4.11.5 | 0.454 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.454 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.454 | |
| 2ejk | SAH | Diphthine synthase | / | 0.454 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.454 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.454 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3zho | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.454 | |
| 3zov | WZV | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.454 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.454 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.454 | |
| 5erm | 210 | Fusicoccadiene synthase | 4.2.3.43 | 0.454 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.453 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.453 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1zis | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.453 | |
| 3d5w | ADP | Serine/threonine-protein kinase PLK | / | 0.453 | |
| 4j1c | 1HO | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.453 | |
| 1eqa | MG7 | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase | 2.1.1.57 | 0.452 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.452 | |
| 1v79 | FR7 | Adenosine deaminase | 3.5.4.4 | 0.452 | |
| 1wm1 | PTB | Proline iminopeptidase | 3.4.11.5 | 0.452 | |
| 1y5x | E89 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.452 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.452 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.452 | |
| 3wb5 | 0B4 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1g7u | PEP | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.451 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.451 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.451 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.451 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.451 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.451 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.451 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.451 | |
| 2z1x | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.451 | |
| 2z71 | PNV | Penicillin acylase | 3.5.1.11 | 0.451 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.451 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.451 | |
| 2zhq | 27U | Prothrombin | 3.4.21.5 | 0.451 | |
| 3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.451 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.451 | |
| 3c34 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.451 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.451 | |
| 3n76 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.451 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 4j0p | 1H8 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4j0t | 6T9 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4qjc | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 5fx2 | FMN | Flavodoxin | / | 0.451 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.450 | |
| 1hk5 | T44 | Serum albumin | / | 0.450 | |
| 1k21 | IGN | Prothrombin | 3.4.21.5 | 0.450 | |
| 1pr6 | XYA | Purine nucleoside phosphorylase DeoD-type | / | 0.450 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
| 2emr | SAH | Diphthine synthase | / | 0.450 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.450 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.450 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.450 | |
| 3nt2 | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.450 | |
| 3tpr | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4az2 | 9MU | Prothrombin | 3.4.21.5 | 0.450 | |
| 4z4p | SAH | Histone-lysine N-methyltransferase 2D | 2.1.1.43 | 0.450 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.450 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.449 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.449 | |
| 2oli | IOP | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.449 | |
| 3anm | SYD | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.449 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.449 | |
| 3qji | MGP | Ribosome inactivating protein | / | 0.449 | |
| 3tza | TZG | Glutamate receptor 2 | / | 0.449 | |
| 4dy4 | FMN | NAD(P)H dehydrogenase (quinone) | / | 0.449 | |
| 4gh1 | 0WX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 1bx9 | GLY_GGL_FOE | Glutathione S-transferase F2 | 2.5.1.18 | 0.448 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.448 | |
| 1vhn | FMN | tRNA-dihydrouridine synthase | / | 0.448 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.448 | |
| 2v5u | FMN | Flavodoxin | / | 0.448 | |
| 2vz0 | D64 | Pteridine reductase | / | 0.448 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.448 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.448 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.448 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1a69 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.447 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.447 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.447 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.447 | |
| 1sg0 | STL | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.447 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.447 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.447 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2xnc | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.447 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.447 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.447 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.447 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.447 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.447 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4f79 | P53 | Putative phospho-beta-glucosidase | / | 0.447 | |
| 4j0y | 1H6 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4yao | 2AM | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 5dsg | 0HK | Muscarinic acetylcholine receptor M4 | / | 0.447 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.446 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.446 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.446 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 3qto | 10P | Prothrombin | 3.4.21.5 | 0.446 | |
| 3u8f | FGM | Ribosome inactivating protein | / | 0.446 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.446 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.446 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.446 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.446 | |
| 1c4v | IH2 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.445 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.445 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.445 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.445 | |
| 1p33 | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.445 | |
| 1pf7 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2emu | SAH | Diphthine synthase | / | 0.445 | |
| 2fhk | MFN | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.445 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.445 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.445 | |
| 2yhu | WHF | Pteridine reductase | / | 0.445 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.445 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.445 | |
| 4b6s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
| 4ba5 | PXG | Probable aminotransferase | / | 0.445 | |
| 4c3y | ANB | 3-ketosteroid dehydrogenase | / | 0.445 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.445 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.445 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.445 | |
| 4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.445 | |
| 4z87 | GDP | Inosine-5'-monophosphate dehydrogenase | / | 0.445 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.445 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.444 | |
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.444 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.444 | |
| 2e8q | SAH | Diphthine synthase | / | 0.444 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.444 | |
| 2vnj | FAD | NADPH:ferredoxin reductase | / | 0.444 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.444 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 3pft | FMN | Flavin reductase | / | 0.444 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3vo2 | FAD | Ferredoxin--NADP reductase | / | 0.444 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4rel | KMP | Glycosyltransferase | / | 0.444 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.444 | |
| 5cvf | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 5flj | QUE | Quercetinase QueD | / | 0.444 | |
| 1a4l | DCF | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 1ny2 | ARG_PRO_PRO_GLY | Prothrombin | 3.4.21.5 | 0.443 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.443 | |
| 1vce | SAH | Diphthine synthase | / | 0.443 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.443 | |
| 2cww | SAH | Uncharacterized protein | / | 0.443 | |
| 2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.443 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.443 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.443 | |
| 3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.443 | |
| 3ele | PLP | Aminotransferase | / | 0.443 | |
| 3jq7 | DX2 | Pteridine reductase, putative | / | 0.443 | |
| 3qwc | 98P | Prothrombin | 3.4.21.5 | 0.443 | |
| 3rl4 | 5GP | Metallophosphoesterase MPPED2 | 3.1 | 0.443 | |
| 3v2u | ATP | Protein GAL3 | / | 0.443 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.443 | |
| 4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.443 | |
| 4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4jtp | ASC | Ribosome inactivating protein | / | 0.443 | |
| 5doz | NDP | JamJ | / | 0.443 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.442 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.442 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.442 | |
| 1rgs | CMP | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.442 | |
| 1uhh | CZP | Aequorin-2 | / | 0.442 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.442 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.442 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.442 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 2i8c | ADP | D-alanine--D-alanine ligase | / | 0.442 | |
| 2idv | M7G | Eukaryotic translation initiation factor 4E-1 | / | 0.442 | |
| 2p6l | SAH | Diphthine synthase | / | 0.442 | |
| 2qe2 | 452 | Polyprotein | / | 0.442 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.442 | |
| 3fgo | ACP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.442 | |
| 3zmg | 6Z0 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4iil | RBF | Membrane lipoprotein TpN38(b) | / | 0.442 | |
| 4j7g | TRH | PCZA361.3 | / | 0.442 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.442 | |
| 4xt8 | TMQ | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.442 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.442 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.441 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.441 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1mj3 | HXC | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.441 | |
| 1syn | F89 | Thymidylate synthase | / | 0.441 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2i4t | UA2 | Purine nucleoside phosphorylase, putative | / | 0.441 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.441 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.441 | |
| 3uaz | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.441 | |
| 3v97 | SAH | Ribosomal RNA large subunit methyltransferase K/L | 2.1.1.173 | 0.441 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.441 | |
| 4hsh | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.441 | |
| 4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.441 | |
| 4s1h | ADP | Pyridoxal kinase, putative | / | 0.441 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.441 | |
| 2rh1 | CAU | Beta-2 adrenergic receptor | / | 0.441 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.440 | |
| 1xvv | CCQ | L-carnitine CoA-transferase | / | 0.440 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.440 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.440 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.440 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
| 4b4g | KKT | Glucose-1-phosphate thymidylyltransferase | / | 0.440 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.440 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.440 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.440 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
| 5ex0 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.440 |