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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1gih1PUCyclin-dependent kinase 22.7.11.22

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
1gih1PUCyclin-dependent kinase 22.7.11.221.000
3qxpX64Cyclin-dependent kinase 22.7.11.220.604
1v1k3FPCyclin-dependent kinase 22.7.11.220.569
3rni21ZCyclin-dependent kinase 22.7.11.220.552
3r9dX6BCyclin-dependent kinase 22.7.11.220.550
1pxmCK5Cyclin-dependent kinase 22.7.11.220.549
1oiqHDUCyclin-dependent kinase 22.7.11.220.541
3rmf20ZCyclin-dependent kinase 22.7.11.220.538
1gii1PUCyclin-dependent kinase 22.7.11.220.537
3uli1N3Cyclin-dependent kinase 22.7.11.220.535
3rkb12ZCyclin-dependent kinase 22.7.11.220.534
2uznC96Cyclin-dependent kinase 22.7.11.220.530
3rk708ZCyclin-dependent kinase 22.7.11.220.530
3rpv26ZCyclin-dependent kinase 22.7.11.220.530
1ke6LS2Cyclin-dependent kinase 22.7.11.220.529
4fkpLS5Cyclin-dependent kinase 22.7.11.220.529
1p2a5BNCyclin-dependent kinase 22.7.11.220.528
3lfqA28Cyclin-dependent kinase 22.7.11.220.528
1aq1STUCyclin-dependent kinase 22.7.11.220.527
2bheBRYCyclin-dependent kinase 22.7.11.220.525
4erwSTUCyclin-dependent kinase 22.7.11.220.523
2r3lSCWCyclin-dependent kinase 22.7.11.220.521
1ke5LS1Cyclin-dependent kinase 22.7.11.220.520
2w1hL0FCyclin-dependent kinase 22.7.11.220.518
3sqq99ZCyclin-dependent kinase 22.7.11.220.518
2xmyCDKCyclin-dependent kinase 22.7.11.220.517
3rk909ZCyclin-dependent kinase 22.7.11.220.516
4bgh3I6Cyclin-dependent kinase 22.7.11.220.516
3r8zZ63Cyclin-dependent kinase 22.7.11.220.515
1w0xOLOCyclin-dependent kinase 22.7.11.220.512
2r64740Cyclin-dependent kinase 22.7.11.220.512
2btrU73Cyclin-dependent kinase 22.7.11.220.511
3r7iX9ICyclin-dependent kinase 22.7.11.220.510
3s1h56ZCyclin-dependent kinase 22.7.11.220.510
1ke7LS3Cyclin-dependent kinase 22.7.11.220.509
2w06FRVCyclin-dependent kinase 22.7.11.220.508
3sw418KCyclin-dependent kinase 22.7.11.220.508
1oitHDTCyclin-dependent kinase 22.7.11.220.505
2btsU32Cyclin-dependent kinase 22.7.11.220.505
3qu0X40Cyclin-dependent kinase 22.7.11.220.505
3s2pPMUCyclin-dependent kinase 22.7.11.220.505
2fvdLIACyclin-dependent kinase 22.7.11.220.504
3qtzX42Cyclin-dependent kinase 22.7.11.220.504
4fkq42KCyclin-dependent kinase 22.7.11.220.503
3ral04ZCyclin-dependent kinase 22.7.11.220.501
1g5sI17Cyclin-dependent kinase 22.7.11.220.500
2vv9IM9Cyclin-dependent kinase 22.7.11.220.500
4fkt48KCyclin-dependent kinase 22.7.11.220.500
2vthLZ2Cyclin-dependent kinase 22.7.11.220.499
3ezvEZVCyclin-dependent kinase 22.7.11.220.499
3rjc06ZCyclin-dependent kinase 22.7.11.220.499
4fx360KCyclin-dependent kinase 22.7.11.220.499
1ke9LS5Cyclin-dependent kinase 22.7.11.220.498
1h1s4SPCyclin-dependent kinase 22.7.11.220.497
1pyePM1Cyclin-dependent kinase 22.7.11.220.497
4fkg4CKCyclin-dependent kinase 22.7.11.220.497
1h1r6CPCyclin-dependent kinase 22.7.11.220.496
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.496
3le62BZCyclin-dependent kinase 22.7.11.220.496
1di8DTQCyclin-dependent kinase 22.7.11.220.495
1oguST8Cyclin-dependent kinase 22.7.11.220.495
2bhhRYUCyclin-dependent kinase 22.7.11.220.494
2j9mPY8Cyclin-dependent kinase 22.7.11.220.494
2vttLZDCyclin-dependent kinase 22.7.11.220.494
3lfnA27Cyclin-dependent kinase 22.7.11.220.494
3qtuX44Cyclin-dependent kinase 22.7.11.220.494
3qwjX6ACyclin-dependent kinase 22.7.11.220.494
4ek610KCyclin-dependent kinase 22.7.11.220.494
4ez30S0Cyclin-dependent kinase 22.7.11.220.494
3qtxX43Cyclin-dependent kinase 22.7.11.220.493
4fkv61KCyclin-dependent kinase 22.7.11.220.492
3rk507ZCyclin-dependent kinase 22.7.11.220.491
4ez50RSCyclin-dependent kinase 62.7.11.220.491
3qqkX02Cyclin-dependent kinase 22.7.11.220.490
4fki09KCyclin-dependent kinase 22.7.11.220.490
3qzgX67Cyclin-dependent kinase 22.7.11.220.489
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.488
2c6o4SPCyclin-dependent kinase 22.7.11.220.487
3lfsA07Cyclin-dependent kinase 22.7.11.220.487
3ti1B49Cyclin-dependent kinase 22.7.11.220.487
1dm2HMDCyclin-dependent kinase 22.7.11.220.486
1gij2PUCyclin-dependent kinase 22.7.11.220.486
3sw719KCyclin-dependent kinase 22.7.11.220.486
1r78FMDCyclin-dependent kinase 22.7.11.220.485
1urwI1PCyclin-dependent kinase 22.7.11.220.485
2vu3LZECyclin-dependent kinase 22.7.11.220.484
2b55D31Cyclin-dependent kinase 22.7.11.220.483
4ek816KCyclin-dependent kinase 22.7.11.220.483
2iw94SPCyclin-dependent kinase 22.7.11.220.482
4fkw62KCyclin-dependent kinase 22.7.11.220.482
3qxoX65Cyclin-dependent kinase 22.7.11.220.481
2duv371Cyclin-dependent kinase 22.7.11.220.480
2uzoC62Cyclin-dependent kinase 22.7.11.220.480
3qtrX36Cyclin-dependent kinase 22.7.11.220.480
2iw84SPCyclin-dependent kinase 22.7.11.220.479
4fkj11KCyclin-dependent kinase 22.7.11.220.479
2xnbY8LCyclin-dependent kinase 22.7.11.220.478
4acm7YGCyclin-dependent kinase 22.7.11.220.478
1h0w207Cyclin-dependent kinase 22.7.11.220.477
4fkr45KCyclin-dependent kinase 22.7.11.220.477
3qtqX35Cyclin-dependent kinase 22.7.11.220.476
1ke8LS4Cyclin-dependent kinase 22.7.11.220.475
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.475
3fz1B98Cyclin-dependent kinase 22.7.11.220.475
3r9hZ67Cyclin-dependent kinase 22.7.11.220.475
2vtiLZ3Cyclin-dependent kinase 22.7.11.220.474
2w17I19Cyclin-dependent kinase 22.7.11.220.474
3qqfX07Cyclin-dependent kinase 22.7.11.220.474
3r73X87Cyclin-dependent kinase 22.7.11.220.474
1ckpPVBCyclin-dependent kinase 22.7.11.220.473
1ykr628Cyclin-dependent kinase 22.7.11.220.473
3ddpRC8Cyclin-dependent kinase 22.7.11.220.473
3r9oZ71Cyclin-dependent kinase 22.7.11.220.473
4nj32KDCyclin-dependent kinase 22.7.11.220.472
3r1yX76Cyclin-dependent kinase 22.7.11.220.471
4fko20KCyclin-dependent kinase 22.7.11.220.471
3rm719ZCyclin-dependent kinase 22.7.11.220.470
4eok4SPCyclin-dependent kinase 22.7.11.220.469
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.467
3ddqRRCCyclin-dependent kinase 22.7.11.220.467
3iggEFQCyclin-dependent kinase 22.7.11.220.467
1w8cN69Cyclin-dependent kinase 22.7.11.220.466
2r3kSCQCyclin-dependent kinase 22.7.11.220.466
1pkdUCNCyclin-dependent kinase 22.7.11.220.465
4lyn1YGCyclin-dependent kinase 22.7.11.220.464
1vyw292Cyclin-dependent kinase 22.7.11.220.463
2r3iSCFCyclin-dependent kinase 22.7.11.220.463
1fvt106Cyclin-dependent kinase 22.7.11.220.462
3raiX85Cyclin-dependent kinase 22.7.11.220.462
3s0o50ZCyclin-dependent kinase 22.7.11.220.462
4eor4SPCyclin-dependent kinase 22.7.11.220.462
1fvv107Cyclin-dependent kinase 22.7.11.220.461
2c6tDT5Cyclin-dependent kinase 22.7.11.220.461
2uzdC85Cyclin-dependent kinase 22.7.11.220.461
2a0cCK9Cyclin-dependent kinase 22.7.11.220.460
1b39ATPCyclin-dependent kinase 22.7.11.220.459
1vyzN5BCyclin-dependent kinase 22.7.11.220.459
3rpy27ZCyclin-dependent kinase 22.7.11.220.458
4bcnT9NCyclin-dependent kinase 22.7.11.220.458
4bcpT3CCyclin-dependent kinase 22.7.11.220.458
2r3p3SCCyclin-dependent kinase 22.7.11.220.457
3r1sX73Cyclin-dependent kinase 22.7.11.220.457
2wpa889Cyclin-dependent kinase 22.7.11.220.456
3ig7EFPCyclin-dependent kinase 22.7.11.220.456
3qwkX62Cyclin-dependent kinase 22.7.11.220.456
3roy22ZCyclin-dependent kinase 22.7.11.220.455
3rpo24ZCyclin-dependent kinase 22.7.11.220.455
2uzeC95Cyclin-dependent kinase 22.7.11.220.454
4fks46KCyclin-dependent kinase 22.7.11.220.454
1oiyN41Cyclin-dependent kinase 22.7.11.220.453
2c5nCK8Cyclin-dependent kinase 22.7.11.220.453
2vtsLZCCyclin-dependent kinase 22.7.11.220.453
2wxvWXVCyclin-dependent kinase 22.7.11.220.453
3r6xX84Cyclin-dependent kinase 22.7.11.220.453
2c6iDT1Cyclin-dependent kinase 22.7.11.220.452
2vtrLZBCyclin-dependent kinase 22.7.11.220.452
3r7yZ04Cyclin-dependent kinase 22.7.11.220.452
3tnwF18Cyclin-dependent kinase 22.7.11.220.452
4eon1ROCyclin-dependent kinase 22.7.11.220.452
1pxkCK3Cyclin-dependent kinase 22.7.11.220.451
3wblPDYCyclin-dependent kinase 22.7.11.220.451
3pj8404Cyclin-dependent kinase 22.7.11.220.450
1oi9N20Cyclin-dependent kinase 22.7.11.220.449
2eufLQQCyclin-dependent kinase 62.7.11.220.449
3unk0BYCyclin-dependent kinase 22.7.11.220.449
2i40BLZCyclin-dependent kinase 22.7.11.220.448
2r3r6SCCyclin-dependent kinase 22.7.11.220.448
2wihP48Cyclin-dependent kinase 22.7.11.220.448
3r83Z14Cyclin-dependent kinase 22.7.11.220.448
1v0pPVBCell division control protein 2 homolog2.7.11.220.447
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.447
2x1nX1NCyclin-dependent kinase 22.7.11.220.447
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.447
3qzhX69Cyclin-dependent kinase 22.7.11.220.447
4fklCK2Cyclin-dependent kinase 22.7.11.220.447
4qmpDKISerine/threonine-protein kinase 242.7.11.10.447
2r3jSCJCyclin-dependent kinase 22.7.11.220.446
3r7uX96Cyclin-dependent kinase 22.7.11.220.445
3r8lZ30Cyclin-dependent kinase 22.7.11.220.445
3rm618ZCyclin-dependent kinase 22.7.11.220.445
1e1xNW1Cyclin-dependent kinase 22.7.11.220.444
2a4lRRCCyclin-dependent kinase 22.7.11.220.444
1oirHDYCyclin-dependent kinase 22.7.11.220.443
2exmZIPCyclin-dependent kinase 22.7.11.220.443
3nup3NUCyclin-dependent kinase 62.7.11.220.443
3rzb02ZCyclin-dependent kinase 22.7.11.220.443
3bhtMFRCyclin-dependent kinase 22.7.11.220.442
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.441
3qzfX66Cyclin-dependent kinase 22.7.11.220.441
2c69CT8Cyclin-dependent kinase 22.7.11.220.440
3py0SU9Cyclin-dependent kinase 22.7.11.220.440