sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 1.000 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.456 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.456 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.456 | |
| 2bxm | IMN | Serum albumin | / | 0.452 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.448 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.447 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.446 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.446 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.445 | |
| 4ckc | SAH | mRNA-capping enzyme catalytic subunit | 2.1.1.56 | 0.443 | |
| 1cg3 | IMO | Adenylosuccinate synthetase | / | 0.440 | |
| 3r9i | ADP | Septum site-determining protein MinD | / | 0.440 |