sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1g27 | BB1 | Peptide deformylase | 3.5.1.88 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1g27 | BB1 | Peptide deformylase | 3.5.1.88 | 1.000 | |
| 1g2a | BB2 | Peptide deformylase | 3.5.1.88 | 0.635 | |
| 1lru | BB2 | Peptide deformylase | 3.5.1.88 | 0.572 | |
| 3k6l | 2BB | Peptide deformylase | 3.5.1.88 | 0.516 | |
| 3u04 | BB2 | Peptide deformylase | / | 0.493 | |
| 4e9a | QAP | Peptide deformylase | / | 0.483 | |
| 2ew5 | Y12 | Peptide deformylase | / | 0.474 | |
| 1ix1 | BB2 | Peptide deformylase | / | 0.472 | |
| 3o3j | BB4 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.471 | |
| 3m6p | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.469 | |
| 1l3i | SAH | Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) | / | 0.467 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.466 | |
| 2ew6 | Y13 | Peptide deformylase | / | 0.459 | |
| 3pn4 | BB2 | Peptide deformylase 1B, chloroplastic/mitochondrial | 3.5.1.88 | 0.459 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.456 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 3t4n | ADP | 5'-AMP-activated protein kinase subunit gamma | / | 0.456 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.454 | |
| 1civ | NAP | Malate dehydrogenase [NADP], chloroplastic | 1.1.1.82 | 0.453 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.452 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.451 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.450 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.450 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.447 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.447 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.446 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.445 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.444 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.444 | |
| 4uir | FAD | Oleate hydratase | 4.2.1.53 | 0.443 | |
| 1qf4 | RPD | Adenylosuccinate synthetase | / | 0.441 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.440 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.440 | |
| 4qxr | 1YE | Stimulator of interferon genes protein | / | 0.440 |